Method for preparing wall-broken ganoderma lucidum spore powder capsules

A technology of broken Ganoderma lucidum spore powder and spore powder, which can be used in capsule delivery, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems of low spore wall breaking rate, difficulty in achieving satisfactory results, and easy residue. To achieve the effect of improving the efficiency of mechanical crushing

Active Publication Date: 2015-12-02
福建省幸福生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, Ganoderma lucidum spores are surrounded by hard chitin fibers, which are difficult for the human body to fully absorb, and direct consumption is likely to cause waste. Therefore, the broken Ganoderma lucidum spores are more suitable for direct absorption by the human stomach.
[0003] At present, the method of breaking the wall of Ganoderma lucidum spore powder is mainly divided into mechanical method, physical method, chemical method and biological enzymatic method. It is easy to remain, and the spore wall breaking rate is not high after mechanical and physical methods, so it is difficult to achieve satisfactory results

Method used

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Embodiment 1

[0017] A kind of preparation method of broken ganoderma lucidum spore powder capsule, it specifically comprises the following steps:

[0018] 1) Inoculate Trichoderma viride in PDA liquid medium, ferment and culture at 35°C for 5 days, centrifuge, and take the supernatant;

[0019] 2) Add 1.5 times the volume of water to the collected spore powder, then add 0.5% of the weight of the spore powder to the supernatant obtained in step 1), mix it and place it for 8 hours, and stir it slowly once;

[0020] 3) According to the amount of 10mL diluted hydrochloric acid with a mass concentration of 10% per 1000mL of feed liquid, the dilute hydrochloric acid added to the feed liquid obtained in step 2) is mixed and then intermittently shaken at 38°C, that is, shake for 40s and then stop for 20s , circulated for 10 minutes, then slowly filtered, and washed the spore powder left on the filter membrane with water for 3 times;

[0021] 4) Dry the washed spore powder at 80°C for 5 hours, the...

Embodiment 2

[0024] A kind of preparation method of broken ganoderma lucidum spore powder capsule, it specifically comprises the following steps:

[0025] 1) Inoculate Trichoderma viride in PDA liquid medium, ferment and culture at 32°C for 6 days, centrifuge, and take the supernatant;

[0026] 2) Add 1.3 times the volume of water to the collected spore powder, then add 0.6% of the weight of the spore powder to the supernatant obtained in step 1), mix it and place it for 9 hours, and stir it slowly once;

[0027] 3) According to the amount of 12mL diluted hydrochloric acid with a mass concentration of 10% per 1000mL of feed liquid, the dilute hydrochloric acid added to the feed liquid obtained in step 2) is mixed and then intermittently shaken at 32°C, that is, shake for 40s and then stop for 20s , circulated for 15 minutes, then slowly filtered, and washed the spore powder left on the filter membrane with water for 3 times;

[0028] 4) Dry the washed spore powder at 60°C for 6 hours, the...

Embodiment 3

[0031] A kind of preparation method of broken ganoderma lucidum spore powder capsule, it specifically comprises the following steps:

[0032] 1) Inoculate Trichoderma viride in PDA liquid medium, ferment and cultivate at 30°C for 8 days, centrifuge, and take the supernatant;

[0033] 2) Add 1.2 times the volume of water to the collected spore powder, then add 0.8% of the weight of the spore powder to the supernatant obtained in step 1), mix well and place it for 10 hours, stirring slowly once during the period;

[0034] 3) According to the amount of 15mL diluted hydrochloric acid with a mass concentration of 10% per 1000mL of feed liquid, the dilute hydrochloric acid added to the feed liquid obtained in step 2) is mixed and then intermittently shaken at 35°C, that is, shake for 40s and then stop for 20s , circulated for 20 minutes, then slowly filtered, and washed the spore powder left on the filter membrane twice with water;

[0035] 4) Dry the washed spore powder at 50°C fo...

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Abstract

The invention discloses a method for preparing wall-broken ganoderma lucidum spore powder capsules. First trichoderma viride is cultivated, obtained metabolites are utilized to process collected ganoderma lucidum spore powder, diluted hydrochloric acid is added and then intermittent oscillation processing is performed, so that the spore wall is loosened, the treated spore powder undergoes washing, drying, mechanical crushing and ultraviolet sterilization, and the wall-broken ganoderma lucidum spore powder capsules are obtained. Compared with the case that the wall-broken rate byconventional physical and mechanical crushing is low and it is difficult to achieve the satisfactory wall-broken effects, the method is simple to operate, the mechanical wall breaking is adopted after treatment, so that the wall-broken rate of obtained ganoderma lucidum spores is over 99% and even reaches 100%, and accordingly nutritional ingredients in the ganoderma lucidum spore powder can be released better to be directly absorbed by the human intestines and stomach.

Description

technical field [0001] The invention belongs to the technical field of medical and health product processing, and in particular relates to a preparation method of a broken ganoderma lucidum spore powder capsule. Background technique [0002] Ganoderma lucidum has been regarded by physicians of all dynasties as a good tonic for nourishing, strengthening, nourishing the middle and Qi. Modern medical research has also proved that Ganoderma lucidum has multiple functions such as anti-oxidation, anti-inflammation, anti-tumor, liver protection, and immune regulation. The extremely tiny oval germ cells ejected from the gills of Ganoderma lucidum—Ganoderma lucidum spores are considered to condense the essence of Ganoderma lucidum because they have all the genetic material of Ganoderma lucidum. However, Ganoderma lucidum spores are surrounded by hard chitin fibers, which are difficult for the human body to fully absorb, and direct consumption is likely to cause waste. Therefore, the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074A61K9/48A61P35/00A61P37/02
Inventor 王雪竹王县福
Owner 福建省幸福生物科技有限公司
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