Traditional Chinese medicine for treating hashimoto thyroiditis and preparation method thereof

A technology for thyroiditis and Hashimoto's, which is applied in the field of traditional Chinese medicine for treating Hashimoto's thyroiditis and its preparation, and can solve the problems of high recurrence rate, inability to reduce anti-thyroid autoantibodies, and small direct effect.

Inactive Publication Date: 2015-12-02
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Thyroid hormone replacement therapy cannot reduce the high titer of anti-thyroid autoantibodies in the patient's serum, and has little direct effect on the autoimmune pathogenic process of the patient
Adrenal cortex hormone therapy also requires long-term use, and its adverse reactions are manifold, and the recurrence rate is high

Method used

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  • Traditional Chinese medicine for treating hashimoto thyroiditis and preparation method thereof
  • Traditional Chinese medicine for treating hashimoto thyroiditis and preparation method thereof
  • Traditional Chinese medicine for treating hashimoto thyroiditis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A traditional Chinese medicine for the treatment of Hashimoto’s thyroiditis. Its raw materials are composed of 13 parts by weight of Bupleurum vulgare, 19 parts of Prunella vulgaris, 9 parts of black medicine, 7 parts of bergamot, 6 parts of Fritillaria fritillariae and 18 parts of Scrophulariaceae , 20 parts of Radix Rehmanniae, 19 parts of White Peony, 18 parts of Radix Astragali, 10 parts of Angelica, 8 parts of Saponin, 14 parts of Dandelion, 8 parts of Daqingye, 7 parts of Weilingxian, 9 parts of Platycodon grandiflorum.

[0028] Preparation:

[0029] (1) Extraction of medicines containing volatile oil: add Bupleurum, Radix Scutellariae, Bergamot, and Angelica to 4 times the weight of these medicines, distill the volatile oil for 6 hours, collect the volatile oil, and use it as spare volatile oil. The distilled water is collected in another device, combined in the water decoction and concentrated, and the medicine dregs are combined in the water decoction and alcohol pr...

Embodiment 2

[0036] A traditional Chinese medicine for the treatment of Hashimoto’s thyroiditis. Its raw materials are composed of 17 parts by weight of Bupleurum vulgare, 21 parts of Prunella vulgaris, 11 parts of black medicine, 9 parts of bergamot, 8 parts of Fritillaria spp. and 22 parts of Scrophulariaceae , 23 parts of Radix Rehmanniae, 24 parts of White Peony, 22 parts of Radix Astragali, 12 parts of Angelica, 11 parts of Saponaria japonicus, 18 parts of Dandelion, 12 parts of Daqingye, 10 parts of Weilingxian, 11 parts of Platycodon grandiflorum

[0037] Preparation:

[0038] (1) Extraction of volatile oil-containing drugs: add Bupleurum, Radix Aconitum, Bergamot, and Angelica to water 10 times the mass of these drugs, distill the volatile oil for 8 hours, collect the volatile oil, and use it as a spare volatile oil. The distilled water is collected in another device, combined in the water decoction and concentrated, and the medicine dregs are combined in the water decoction and alcohol...

Embodiment 3

[0045] A traditional Chinese medicine for the treatment of Hashimoto’s thyroiditis. Its raw materials are composed of 12 parts by weight of Bupleurum vulgare, 18 parts of Prunella vulgaris, 8 parts of black medicine, 6 parts of bergamot, 5 parts of Fritillaria spp. , 19 parts of Radix Rehmanniae, 18 parts of Radix Paeoniae Alba, 16 parts of Astragalus, 9 parts of Angelica, 7 parts of Saponin, 13 parts of Dandelion, 7 parts of Daqingye, 6 parts of Wei Lingxian, 8 parts of Platycodon grandiflorum.

[0046] Preparation:

[0047] (1) Extraction of medicines containing volatile oil: add Bupleurum, Aconite, Bergamot, and Angelica to 5 times the mass of these medicines in water, distill the volatile oil for 4 hours, collect the volatile oil and use it as a spare volatile oil. The distilled water is collected in another device, combined in the water decoction and concentrated, and the medicine residue is combined in the water decoction and alcohol precipitation medicine for decoction;

[00...

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Abstract

The invention relates to traditional Chinese medicine for treating hashimoto thyroiditis and a preparation method thereof. The traditional Chinese medicine for treating the hashimoto thyroiditis is prepared from, by weight, 8-22 parts of Chinese thorowax roots, 13-27 parts of spica prunellae, 5-17 parts of combined spicebush roots, 4-13 parts of fructus citri sarcodactylis, 3-11 parts of thunberg fritillary bulbs, 13-28 parts of figwort roots, 15-26 parts of radix rehmanniae, 12-27 parts of radix paeoniae alba, 10-26 parts of milkvetch roots, 6-16 parts of angelica sinensis, 5-15 parts of spina gleditsiae, 10-21 parts of herba taraxaci, 6-15 parts of folium isatidis, 5-13 parts of clematis roots and 6-14 parts of radix platycodonis. Water is added in a mixture of Chinese thorowax roots, combined spicebush roots, fructus citri sarcodactylis and angelica sinensis, distillation is conducted to extract volatile oil, inclusion of beta- cyclodextrin is conducted on the volatile oil for standby, dregs of a decoction is mixed with other drugs after distillation, water is added in the mixture, concentration is conducted after the mixture is decocted, concentration is conducted after alcohol precipitation is conducted on a concentrated solution, auxiliary materials are added after concentration, spray drying is conducted, and mixing and granulation are conducted on drug powder, a beta-cyclodextrin inclusion complex of the volatile oil and the like. The traditional Chinese medicine for treating the hashimoto thyroiditis has the effects of regulating Qi, smoothing depression, dissipating phlegm, clearing heat, resolving lumps and removing galls.

Description

Technical field [0001] The invention relates to a Chinese medicine, in particular to a Chinese medicine for treating Hashimoto's thyroiditis and a preparation method thereof. Background technique [0002] Chronic lymphocytic thyroiditis (Hashimotothyroiditis, HT) is a common disease and frequently-occurring disease. The incidence in my country is about 0.3-1.5 / 1000. It is more common in women, with a ratio of about 1:20. Among them, the peak period of onset is 30-60 years old, which can be seen in children and the elderly. At present, with the accelerated pace of life, increased work pressure, and changes in diet, the incidence of chronic lymphocytic thyroiditis (HT) is increasing year by year and becoming younger. At present, the treatment of chronic lymphocytic thyroiditis (HT) by western medicine mainly adopts thyroid hormone replacement therapy, immunotherapy and surgical treatment. Thyroid hormone replacement therapy cannot reduce the high titer of anti-thyroid autoantibodi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61P29/00A61P37/02
Inventor 王杰王平刘善新梁瑞雪靳光乾杨华杰
Owner SHANDONG PROVINCIAL HOSPITAL
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