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Antibacterial and itching-relieving medicine composition and preparing method thereof

A composition and medicine technology, applied in the field of medicine, can solve the problems of large differences in chemical properties of antibacterial active ingredients, insignificant sterilization and antipruritic effects, and inability to fully utilize raw materials, etc., and achieves good antibacterial and antipruritic activity and short treatment time. , the effect of reducing individual differences

Active Publication Date: 2015-12-23
湖南知达医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent CN102949647B discloses a pharmaceutical composition for sterilizing and relieving itching. , licorice and borneol, the composition is complicated, the preparation method is simple, the raw materials cannot be fully utilized, and its effect needs to be improved
[0006] Therefore, the traditional Chinese medicine preparations made of general Chinese herbal medicines are due to the large difference in chemical properties of various antibacterial active ingredients, the bactericidal and antipruritic effects are not obvious, and they are easy to relapse after being effective, and cannot be cured. It is necessary to develop a safe and effective Medicinal composition for quick relief of itching

Method used

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  • Antibacterial and itching-relieving medicine composition and preparing method thereof
  • Antibacterial and itching-relieving medicine composition and preparing method thereof
  • Antibacterial and itching-relieving medicine composition and preparing method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0041] The pharmaceutical composition of this example is prepared from the following raw materials in parts by weight: Kochia scoparia 5kg, calamine 5kg, peppermint 3kg and borneol 1.5kg.

[0042] The preparation method of the present embodiment pharmaceutical composition is as follows:

[0043] S1, take borneol, pulverize, pass through a 100-mesh sieve to obtain borneol fine powder, and set aside; take the rest of the medicinal materials, wash and dry, then pulverize respectively, and pass through a 80-mesh sieve;

[0044] S2. Except for borneol, mix the rest of the fine powder of the medicinal materials, add water 10 times the weight of the medicinal materials, and then add cellulase at 1.2% of the weight of the medicinal materials, soak for 1 hour, then decoct twice for 2 hours each time, filter and keep the filter residue , combining the filtrates, concentrating the filtrate under reduced pressure to an extract with a relative density of 1.20 at 60°C to obtain a water extr...

Embodiment 2

[0049] The pharmaceutical composition of this example is prepared from the following raw materials in parts by weight: Kochia scoparia 4kg, calamine 4kg, peppermint 2kg and borneol 1kg.

[0050] The preparation method of the pharmaceutical composition of this embodiment is the same as that of Example 1 to obtain the pharmaceutical composition of this embodiment.

[0051] Take paraffin wax, glyceryl monostearate, white petrolatum, liquid paraffin, Span 40, emulsifier OP and ethyl p-hydroxybenzoate that are filed into fine powder, heat and melt on a water bath and keep at 80°C, finely Add water at the same temperature, and stir until it condenses to obtain a W / O emulsion matrix; take the above-mentioned pharmaceutical composition of this example and place it in a mortar, add the prepared W / O emulsion matrix in portions and grind until uniform , to obtain the cream of the pharmaceutical composition of the present embodiment.

Embodiment 3

[0053] The pharmaceutical composition of this example is prepared from the following raw materials in parts by weight: Kochia scoparia 8kg, calamine 8kg, peppermint 5kg and borneol 3kg.

[0054] The preparation method of the pharmaceutical composition of this embodiment is the same as that of Example 1 to obtain the pharmaceutical composition of this embodiment.

[0055] Take the above-mentioned pharmaceutical composition of this embodiment, add purified water, stir, then add sodium alginate, stir evenly to obtain the lotion of the pharmaceutical composition of this embodiment.

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Abstract

The invention discloses an antibacterial and itching-relieving medicine composition and a preparing method thereof. The medicine composition is prepared from, by weight, 4 parts to 8 parts of fructus kochiae, 4 parts to 8 parts of calamine, 2 parts to 5 parts of mint and 1 part to 3 parts of borneol, and further comprises 6 parts to 10 parts of folium artemisiae argyi, 2 parts to 6 parts of radix sophorae flavescentis, 1 part to 4 parts of rhizoma atractylodis, 4 parts to 8 parts of folium mori, 2 parts to 6 parts of coptis chinensis, 2 parts to 6 parts of cortex phellodendri, 2 parts to 5 parts of semen plantaginis, 4 parts to 8 parts of lophatherum gracile and 4 parts to 8 parts of stephania tetrandra. The antibacterial and itching-relieving medicine composition has the effects of effectively resisting bacteria and rapidly relieving itching, the clinical cure rate for superficial-part fungal diseases is high, treatment time is short, relapsing is avoided after curing, and good application prospects are achieved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antibacterial and antipruritic pharmaceutical composition and a preparation method thereof. Background technique [0002] Pathogenic fungi invade the human body and cause fungal infections. Fungal infectious diseases are divided into 4 categories according to the parts of the fungal invasion of the human body: superficial mycosis, skin mycosis, subcutaneous tissue mycosis and systemic mycosis; the former two are collectively referred to as Superficial mycosis, the latter two are also called deep mycosis, among which superficial mycosis occupies a high proportion, it is generally easy to relapse and difficult to cure, and belongs to one of the intractable skin diseases. Clinically common superficial fungal diseases include tinea manuum, tinea pedis, jock itch, tinea corporis and tinea capitis, etc., which can be contagious. Clinically, it is mostly vesicular and s...

Claims

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Application Information

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IPC IPC(8): A61K36/70A61K36/899A61P31/04A61P17/04
Inventor 卞国良赵振伟
Owner 湖南知达医药科技有限公司
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