Acne-removing traditional Chinese medicine composition and preparation method thereof

A technology of composition and traditional Chinese medicine, which is applied in the field of anti-acne traditional Chinese medicine composition and its preparation, can solve the problems of not being too large in use, having large side effects, and not suitable for long-term use, etc., and achieves a high yield rate and effective ingredients. Fast-acting, non-irritating effect

Inactive Publication Date: 2015-12-23
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] However, among the various medicines used to treat acne at present, Western medicine occupies a huge proportion. Although this kind of medicine can ac

Method used

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  • Acne-removing traditional Chinese medicine composition and preparation method thereof
  • Acne-removing traditional Chinese medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1: Acne-removing traditional Chinese medicine composition of the present invention

[0049] 1. Crush the peel of mangosteen, thyme and citrus aurantium respectively, pass through a 60-mesh sieve, and mix according to the ratio of 80g of mangosteen peel, 20g of thyme, and 20g of citrus aurantium;

[0050] 2. Reflux extraction with 95% ethanol-water solution 12 times the weight of medicinal materials for 2.5 hours;

[0051] 3. Filter the above extract with a 100-mesh filter cloth to remove medicinal residues, concentrate under reduced pressure (temperature 60-80°C, vacuum degree ≥0.08Mpa, the same below), and obtain a concentrated solution with a specific gravity of 1.08 and a weight of 72g;

[0052] 4. Prepare the recovered ethanol-water solution with a concentration of 80%, add it to the concentrated solution at a volume ratio of ethanol-water solution:concentrated solution of 6:1, stir and dissolve at 80°C for 2 hours, and refrigerate overnight at 4°C for 18...

Embodiment 2

[0056] Embodiment 2: Acne-removing traditional Chinese medicine composition of the present invention

[0057] 1. Grind mangosteen peel, thyme, and aurantium husk respectively, pass through a 60-mesh sieve, and mix according to the ratio of 60g of mangosteen peel, 10g of thyme, and 10g of aurantium aurantium;

[0058] 2. Reflux extraction with 60% ethanol-water solution 8 times the weight of medicinal materials for 1 hour;

[0059] 3. Subtract the above extract with a 100-mesh filter cloth to filter out medicinal residues, concentrate under reduced pressure (temperature 60-80°C, vacuum degree ≥0.08Mpa, the same below), and obtain a concentrated solution with a specific gravity of 1.08 and a weight of 106g;

[0060] 4. Prepare the recovered ethanol-water solution with a concentration of 60%, add it to the concentrated solution at a volume ratio of ethanol-water solution:concentrated solution of 4:1, stir and dissolve at 50°C for 0.5h, and refrigerate overnight at 0°C for 12h;

...

Embodiment 3

[0064] Embodiment 3: Acne-removing traditional Chinese medicine composition of the present invention

[0065] 1. Grind the peel of mangosteen, thyme, and citrus aurantium respectively, pass through a 60-mesh sieve, and mix according to the ratio of 80g of mangosteen peel, 10g of thyme, and 10g of citrus aurantium;

[0066] 2. Reflux extraction with 75% ethanol-water solution 10 times the weight of medicinal materials for 2 hours;

[0067] 3. Subtract the above extract with a 100-mesh filter cloth to filter out the medicinal residues, concentrate under reduced pressure (temperature 60-80°C, vacuum degree ≥0.08Mpa, the same below), and obtain a concentrated solution with a specific gravity of 1.06 and a weight of 106g;

[0068] 4. Prepare the recovered ethanol-water solution with a concentration of 70%, add it to the concentrated solution at a volume ratio of ethanol-water solution:concentrated solution of 5:1, stir and dissolve at 60°C for 1.5h, and refrigerate overnight at 2°C...

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Abstract

The invention belongs to the field of traditional Chinese medicine and particularly relates to an acne-removing traditional Chinese medicine composition and a preparation method thereof. The acne-removing traditional Chinese medicine composition comprises mangosteen peel, thyme and fructus aurantii. Mouse dermatitis model anti-inflammation effect tests and bacteriostatic experiments of propionibacterium acnes prove that the traditional Chinese medicine composition is good in inhibitory effect on the propionibacterium acnes and good in anti-inflammation effect, the three medicinal materials of the composition have a synergic anti-inflammation effect, and the composition is fast to become effective, good in effect, safe and mild, non-irritant, free of side effects, capable of being used for a long time, and widely applicable to adolescent or adult people troubled by acne for a long time. The preparation method of the traditional Chinese medicine composition is simple to operate and suitable for industrial production.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for removing acne and a preparation method thereof. Background technique [0002] Acne (also known as acne, acne, acne vulgaris, acne) is a common skin disease that can cause inflammation of the sebaceous glands or hair follicles on the human skin. When local lesions occur, it will produce white or milky white broken rice-like powder juice spiny papules. The occurrence of acne is mainly closely related to factors such as excessive sebum secretion, pilosebaceous gland duct blockage, bacterial infection and inflammatory response. After entering puberty, the level of androgen in the human body, especially testosterone, increases rapidly, which promotes the development of sebaceous glands and produces a large amount of sebum. At the same time, abnormal keratinization of the pilosebaceous duct causes duct blockage, se...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P17/10
CPCA61Q19/00A61K9/0014A61K36/38A61K2236/00A61K2800/5922A61K8/9789A61K8/9783A61K47/46A61K36/752A61K36/53A61P17/00A61P17/10A61P29/00A61P31/04A61P43/00A61K2300/00A61K8/96
Inventor 刘光荣邓文娟
Owner INFINITUS (CHINA) CO LTD
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