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Tablet for treating peptic ulcer and preparation method of tablet

A technology for peptic ulcer and tablet is applied in the field of treatment of peptic ulcer tablet and its preparation, which can solve the problems of insoluble in water and loss of active ingredients, and achieve the effects of improving efficacy and activity and reasonable compatibility.

Inactive Publication Date: 2016-01-06
CHENGDU HENGLING TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, traditional Chinese medicinal materials are mostly decocted in water, but some active ingredients are not easily soluble in water, or are lost during the decoction process. Therefore, in order to make better use of medicinal material resources, it is necessary to prepare pharmaceutical compositions method for research

Method used

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  • Tablet for treating peptic ulcer and preparation method of tablet
  • Tablet for treating peptic ulcer and preparation method of tablet
  • Tablet for treating peptic ulcer and preparation method of tablet

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Effect test

Embodiment 1

[0034] The preparation of embodiment 1 tablet of the present invention

[0035] (1) Preparation of granules

[0036] Atractylodes macrocephala 10g, Poria cocos 10g, red bean 10g, astragalus 7.5g, capillary 7.5g, dandelion 7.5g, bitter almond 5g, bellflower 5g, patchouli 5g, dried ginger 2.5g, ginseng 2.5g; other herbs except ginseng , first add 10 times the amount of 70% ethanol solution for reflux extraction once, extract for 1 hour, filter, and use the filtrate for later use, and decoct the filter residue twice with water, add 8 times the amount of water each time, decoct for 30 minutes each time, and combine the ethanol extract After decoction with water, concentrate to a thick paste with a relative density of 1.28-1.30 (60°C), then add ginseng powder and microcrystalline cellulose in a total of 25-30 g, wet granulate, and dry to obtain the granules of the present invention .

[0037] After measurement, the dry paste rate of the extraction method of the present invention is...

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Abstract

The invention discloses a tablet for treating peptic ulcer; the tablet is prepared by tabletting 100 parts by weight of granules and 1-5 parts by weight of a lubricant, wherein the granules consist of the following raw materials: 7-13 parts of bighead atractylodes rhizome, 7-13 parts of poria cocos, 7-13 parts of seed of vigna umbellata, 5-10 parts of radix astragali, 5-10 parts of herba artemisiae scopariae, 5-10 parts of dandelion, 3-7 parts of bitter apricot seed, 3-7 parts of radix platycodi, 3-7 parts of stem or leaf of pogostemon cablin, 2-3 parts of dried ginger and 2-3 parts of ginseng. The medicine, which is prepared from a few of medicinal materials on the basis of a special dosage ratio, is effective on treating gastric ulcer, duodenal ulcer and erosive gastritis; therefore, a new choice is provided for clinical medication of treating the peptic ulcer. Meanwhile, through a pharmacodynamic test, the preparation method disclosed by the invention, by virtue of double-extracting through alcohol and water and medicating ginseng in the form of powder, can effectively improve pharmacodynamic activity; and the preparation method is beneficial for conservation and utilization of medicinal resources.

Description

technical field [0001] The invention relates to a tablet for treating peptic ulcer and a preparation method thereof. Background technique [0002] Peptic ulcer mainly refers to chronic ulcers that occur in the stomach and duodenum. Among them, gastric and duodenal ulcers refer to localized circular or oval full-thickness defects of the gastric and duodenal mucosa, the muscularis mucosa is penetrated, and fibrous scars are inevitably left after healing. Covered by epithelium, the muscularis mucosa cannot regenerate. The etiology can be summed up as the self-digestion of gastric mucosa by gastric acid and pepsin or the destruction of gastric mucosal barrier due to various reasons. In recent years, it has been considered that the formation of ulcers has an important relationship with Helicobacter pylori infection in the stomach. [0003] Chronic erosive gastritis, also known as verrucous gastritis or pimple-like gastritis, generally only sees dyspepsia symptoms such as fulln...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/20A61P1/04
Inventor 李智叶英杨婷
Owner CHENGDU HENGLING TECH CO LTD
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