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Rapid prototyping preparation method of implant material of plastic surgery

A technology for implant materials and plastic surgery, applied in the field of preparation of biomedical materials, can solve the problems of carrying viruses and bacteria, immune rejection, and limited source of autologous tissue, and achieve no immune rejection, simple operation steps, and good biological phase. capacitive effect

Inactive Publication Date: 2016-01-13
SOUTH CHINA UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Plastic surgery uses surgical methods to transplant various tissues. Autologous tissue or allogeneic tissue can be used. However, the source of autologous tissue is very limited, and a second operation is required, which brings more pain to the patient; allogeneic tissue transplantation also has immune Rejection and risk of carrying viruses and bacteria

Method used

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  • Rapid prototyping preparation method of implant material of plastic surgery
  • Rapid prototyping preparation method of implant material of plastic surgery
  • Rapid prototyping preparation method of implant material of plastic surgery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A rapid prototyping preparation method for implant materials for nose bridge plastic surgery, comprising the following steps:

[0030] (1) Use computer-aided design (CAD) software to design a three-dimensional structural model of the nose bridge plastic part, and save the three-dimensional model as an STL format file, then import it into a three-dimensional printer, and perform layered processing with layering software;

[0031] (2) Add 2 g of polylactic acid-glycolic acid copolymer with a molecular weight of 31,000 and PLA:PGA of 50:50 into the stainless steel barrel of the three-dimensional printer, set the printing temperature to 150°C in the VisualMachines software, and set the platform temperature to 20°C. Leave it for 30 minutes to fully melt and mix the material; then set the needle size to 0.2mm, the extrusion pressure to 3bar, the extrusion speed to 1.5mm / s, the hole diameter to 0.6mm, and the internal structure to be staggered at 0° and 90°, layered The thickn...

Embodiment 2

[0038] A rapid prototyping preparation method for breast plastic implant materials, comprising the following steps:

[0039] (1) Utilize computer-aided design (CAD) software to design the three-dimensional structural model of the breast plastic part, and save the three-dimensional model as an STL format file, then import it into the three-dimensional printer, and carry out layering processing with layering software;

[0040](2) Add 15g of decellularized collagen to 100ml of deionized water, stir for 2 hours until completely dissolved to obtain an aqueous solution of decellularized collagen, filter it, add the filtrate into the barrel of the three-dimensional printer, centrifuge, and let it stand for 24 hours; then in the VisualMachines software Set the printing temperature as room temperature, the platform temperature as 10°C, the needle size as 0.3mm, the extrusion pressure as 1.2bar, the extrusion speed as 3.0mm / s, the hole diameter as 0.8mm, and the internal structure as sta...

Embodiment 3

[0043] A rapid prototyping preparation method for mandibular plastic implant composite materials, comprising the following steps:

[0044] (1) Use computer-aided design (CAD) software to design a three-dimensional structural model of the mandibular plastic part, and save the three-dimensional model as an STL format file, then import it into a three-dimensional printer, and perform layered processing with layering software;

[0045] (2) Add 15g of decellularized collagen to 100ml of deionized water, stir for 2 hours until completely dissolved, and obtain an aqueous solution of decellularized collagen, filter it, add the filtrate into the barrel of the three-dimensional printer, centrifuge, and let it stand for 24 hours. 31,000, PLA:PGA is 50:50 poly(lactic acid-glycolic acid) copolymer into the stainless steel barrel of the 3D printer; then set the printing temperature of the two materials in the VisualMachines software, the printing temperature of collagen is room temperature, ...

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Abstract

The invention discloses a rapid prototyping preparation method of an implant material of a plastic surgery. The method comprises the following steps of designing a three-dimensional structural model of a plastic part by using computer-aided design (CAD) software; importing CAD model data in a three-dimensional printer and performing slicing processing; preparing a biological material into a solution or directly adding the biological material in the three-dimensional printer; setting relevant parameters; starting the three-dimensional printer and printing the model layer by layer; and performing aftertreatment on a prototype to obtain the implant material of the plastic surgery or directly taking the prototype as the implant material of the plastic surgery. An implantable biological material is used for preparing a stent, immunological rejection is not caused, and biological compatibility is good; and moreover, the stent is prepared by a rapid prototyping technology, geometric profile, aperture, porosity and hole distribution of the stent are controlled accurately, a personalized plastic treatment scheme is formulated, a preparation technology is convenient and speedy, operation steps are simple, and an application prospect is wide.

Description

technical field [0001] The invention belongs to the technical field of preparation of biomedical materials, and in particular relates to a rapid prototyping preparation method of orthopedic implant materials. Background technique [0002] It is human nature to love beauty. With the continuous advancement of technology and the improvement of people's economic capabilities, people's pursuit of beauty has become more diverse, and plastic surgery is one of them. Plastic surgery is the use of medical and artistic means to repair and reconstruct the incomplete and deformed human tissues and organs, as well as beautify and reshape the normal human body, so as to restore and reconstruct functions and improve and beautify the shape. Plastic surgery is the transplantation of various tissues by means of surgery. Autologous tissue or allogeneic tissue can be used. However, the source of autologous tissue is very limited, and it will cause a second operation, which will bring more pain t...

Claims

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Application Information

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IPC IPC(8): A61F2/02
Inventor 魏坤胡露
Owner SOUTH CHINA UNIV OF TECH
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