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Tooth desensitizer and preparation and application methods thereof

A technology of desensitization agent and tooth, which is applied in the field of pharmaceutical preparation, can solve the problem of slow onset of action and achieve the effect of alleviating allergic symptoms

Inactive Publication Date: 2016-01-13
常州陀谱生物医学技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its advantage is that it is easy to use, low in price, and does not need to go to the hospital for treatment. Its disadvantage is that the onset of effect is slow and it must be used frequently

Method used

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  • Tooth desensitizer and preparation and application methods thereof
  • Tooth desensitizer and preparation and application methods thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The tooth desensitizing agent of the present invention comprises the following components by mass: 18% of nanoscale hydroxyapatite, 6% of nanoscale calcium hydrogen phosphate, 0.5% of tocopheryl acetate, 42% of glycerol, polyethylene glycol Glycol 4000.8%, Gum Tragacanth 0.2%, Purified Water 24%, Silicon Dioxide 4%, Titanium Dioxide 0.5%, Zinc Oxide 1%, Methylparaben 0.3%, Sodium Lauryl Sulfate 0.7%, Menthol 1%, Natural Eucalyptus Flavor 1%.

[0030] When preparing tooth desensitizers:

[0031] First, weigh ethyl tocopherol, polyethylene glycol 400, glycerin, natural eucalyptus spice, and purified water in proportion, stir and mix evenly, and use it as material A for later use;

[0032] Then, weigh nano-scale hydroxyapatite, nano-calcium hydrogen phosphate, gum tragacanth, silicon dioxide, titanium dioxide, zinc oxide, methyl hydroxybenzoate, sodium lauryl sulfate, menthol in proportion, stir and mix Uniform, as material B for later use;

[0033] Finally, the prepare...

Embodiment 2

[0036] The tooth desensitizing agent of the present invention comprises the following components by mass: 12% of nanoscale hydroxyapatite, 9% of nanoscale calcium hydrogen phosphate, 1% of tocopherol acetate, 45% of glycerol, polyethylene glycol Glycol 4000.7%, Gum Tragacanth 0.3%, Purified Water 22%, Silica 6, Titanium Dioxide 0.1%, Zinc Oxide 0.9%, Methylparaben 0.2%, Sodium Lauryl Sulfate 0.8%, Menthol 0.5 %, Natural Eucalyptus Flavor 1.5%.

[0037] When preparing tooth desensitizers:

[0038] First, weigh ethyl tocopherol, polyethylene glycol 400, glycerin, natural eucalyptus spice, and purified water in proportion, stir and mix evenly, and use it as material A for later use;

[0039] Then, weigh nano-scale hydroxyapatite, nano-calcium hydrogen phosphate, gum tragacanth, silicon dioxide, titanium dioxide, zinc oxide, methyl hydroxybenzoate, sodium lauryl sulfate, menthol in proportion, stir and mix Uniform, as material B for later use;

[0040] Finally, the prepared mat...

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PUM

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Abstract

The invention discloses a tooth desensitizer and preparation and application methods thereof. The tooth desensitizer comprises the following components by mass percent: 13-30 percent of a bioactive material, 0.1-1 percent of tocopheryl acetate, 30-50 percent of glycerin, 0.5-1 percent of polyethyleneglycol 400, 0.1-0.5 percent of an adhesive, 15-25 percent of purified water, 3-7 percent of silicon dioxide, 0.1-0.7 percent of titanium dioxide, 0.5-2 percent of zinc oxide, 0.1-0.5 percent of a preservative, 0.7-1.8 percent of an emulsifier and 1.0-3.0 percent of a spice. A desensitization material used by the tooth desensitizer consists of various inorganic ions, such as silicon, calcium, sodium and phosphorus, and is a material which does not contain antibiotics or fluorides but has a remarkable curative effect on desensitization of teeth. The tooth desensitizer can seal up exposed dentinal tubules relatively deeply to isolate the oral cavity from external irritation so as to achieve the effect of treating dentin hypersensitivity.

Description

technical field [0001] The invention relates to a preparation method of a medicament and an application thereof, in particular to a tooth desensitization agent, a preparation method and an application method thereof. Background technique [0002] The mechanism of dentin hypersensitivity is mainly related to the exposure of dentin and the open state of dentin tubules. The pathogenesis is still unclear. The generation of sensation is related to the sensory nerve in the pulp. That is, disappear. However, there are disputes about how external stimuli are transmitted to the dental pulp, which can be roughly summarized into the following three theories: [0003] (1) Nerve fiber conduction theory: It is believed that there are pulp nerve endings in the dentin, which can transmit the sensation of the surface layer of the dentin to the pulp. If this theory is true, there should be nerve fibers all over the dentine tube, but so far histological studies can only prove the existence o...

Claims

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Application Information

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IPC IPC(8): A61K33/42A61K33/08A61P1/02
Inventor 李晨曦张凯林
Owner 常州陀谱生物医学技术有限公司