The invention provides an oral nursing composition. The oral nursing composition is prepared from a friction agent, a humectant, nipagin esters, complex enzymes, an emulsifier, a nursing auxiliary, multi-vitamin powder, xylitol, essence, a bolete extract and sodium monofluorophosphate; the complex enzymes comprise the lipase, cellulase, pectinase, protease and amylase, and the mass ratio of the lipase to the cellulase to the pectinase to the protease to the amylase is 5:2:1:3:50. The invention further provides a method of the composition. The method comprises the steps of feeding, paste preparing, grinding, vacuum degassing, ageing and filling. The oral nursing composition can synergistically dispel cold evil, clear away heat and toxic materials and obviously inhibit the growth of three kinds of pathogenic bacteria of staphylococcus aureus, escherichia coli and salmonella. The oral nursing composition has a high rate in treating gingival atrophy, minor dental calculi, gingival bleeding, ozostomia and the like, the curative ratio can reach 100%, the treatment course is short, a patient can be cured within 2-8 weeks, the oral nursing composition has no toxin effects, the diseases donot easily relapse, and resistance to drugs is not generated.