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Absorbable medical anti-infective suture line and preparation method

A suture thread and anti-infection technology, applied in the field of medical materials, can solve the problems of poor mechanical properties, rapid degradation and absorption, etc., and achieve the effect of low cost, good biocompatibility, and scientific methods

Inactive Publication Date: 2016-01-20
钊桂英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many different types of collagen, among which type I collagen has the most abundant content, excellent properties, no antigenicity, good biocompatibility, and can participate in the tissue healing process, but the disadvantage is poor mechanical properties and rapid degradation and absorption in the body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1 An absorbable medical anti-infection suture, mainly prepared from the following raw materials (10g each): 8 parts of Shiwei, 6 parts of Ephedra, 9 parts of Cnidium, 7 parts of Jiangxiang, 11 parts of Artemisia argyi, 9 parts of Fangfeng , 5 parts of fleece-flower root, 8 parts of mica, 7 parts of pomegranate peel, 5 parts of mulberry, 9 parts of Dijincao, 6 parts of heart soil, 10 parts of bamboo ginseng, 50 parts of collagen, 12 parts of carboxymethyl chitosan , 3 parts of plasticizer, 2 parts of antibacterial agent, appropriate amount of crosslinking agent.

[0030] The preparation method of above-mentioned a kind of absorbable medical anti-infection suture is:

[0031] (1) Take the pomegranate peel and soak it in rice swill for 2 hours, take it out, dry it, heat the stove core soil in a frying pan, fry until flexible, add the pomegranate peel and sliced ​​ephedra, stir fry over medium heat until the surface of the raw material is burnt yellow, take out; ...

Embodiment 2

[0038] Example 2An absorbable medical anti-infection suture, mainly prepared from the following raw materials (10g each): 16 parts of Shiwei, 10 parts of Ephedra, 17 parts of Cnidium, 15 parts of Jiangxiang, 17 parts of Artemisia argyi, 17 parts of Fangfeng , 12 parts of fleece-flower root, 12 parts of mica, 13 parts of pomegranate peel, 9 parts of mulberry, 12 parts of Dijincao, 9 parts of heart soil, 14 parts of bamboo ginseng, 70 parts of collagen, 20 parts of carboxymethyl chitosan , 8 parts of plasticizer, 6 parts of antibacterial agent, appropriate amount of crosslinking agent.

[0039] A kind of preparation method of absorbable medical anti-infection suture is:

[0040] (1) Take the pomegranate peel and soak it in rice swill for 2 hours, take it out, dry it, heat the stove core soil in a frying pan, fry until flexible, add the pomegranate peel and sliced ​​ephedra, stir fry over medium heat until the surface of the raw material is burnt yellow, take out;

[0041] (2...

Embodiment 3

[0048] Example 3 An absorbable medical anti-infection suture, mainly prepared from the following raw materials (10g per serving): 10 parts of Shiwei, 7 parts of Ephedra, 11 parts of Cnidium, 9 parts of Dalbergia, 13 parts of Artemisia argyi, 11 parts of Fangfeng , 7 parts of fleece-flower root, 9 parts of mica, 9 parts of pomegranate peel, 6 parts of mulberry, 10 parts of Dijincao, 7 parts of heart soil, 11 parts of bamboo ginseng, 55 parts of collagen, 14 parts of carboxymethyl chitosan , 4 parts of plasticizer, 3 parts of antibacterial agent, appropriate amount of crosslinking agent.

[0049] A kind of preparation method of absorbable medical anti-infection suture is:

[0050] (1) Take the pomegranate peel and soak it in rice swill for 2 hours, take it out, dry it, heat the stove core soil in a frying pan, fry until flexible, add the pomegranate peel and sliced ​​ephedra, stir fry over medium heat until the surface of the raw material is burnt yellow, take out;

[0051] ...

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PUM

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Abstract

The invention discloses an absorbable medical anti-infective suture line. The absorbable medical anti-infective suture line is prepared from, by mass, 8-16 parts of herba pyrrosiae, 6-10 parts of ephedra, 9-17 parts of fructus cnidii, 7-15 parts of lignum dalbergiae odoriferae, 11-17 parts of argy wormwood leaves, 9-17 parts of saposhnicovia divaricata, 5-12 parts of radix polygni multiflori, 8-12 parts of mica, 7-13 parts of pomegranate rind, 5-9 parts of herba taxilli, 9-12 parts of humifuse euphorbia herbs, 6-9 parts of furnace soil, 10-14 parts of Japanese ginseng, 50-70 parts of collagen, 12-20 parts of carboxymethyl chitosan, 3-8 parts of plasticizers, 2-6 parts of antibacterial agents and an adequate amount of cross-linking agents. According to the absorbable medical anti-infective suture line, the preparation technology is simple, the method is scientific, the cost is low, large-scale industrial production can be achieved, the prepared product is high in tensile strength and good in flexibility, the biocompatibility is good, the product can be completely absorbed by a human body, the rejecting phenomenon does not exist, the anti-infective effect can be achieved, wound healing is facilitated, and scars are small after healing.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to an absorbable medical anti-infection suture and a preparation method. Background technique [0002] Surgical sutures are commonly used biological textiles, which are widely used in various surgical operations to suture wounds and connect tissues, and are extremely important medical materials. Surgical sutures are sewn into the human body and maintain long-term or lasting contact with human tissues, organs and blood. According to their behavior in living tissues, they can be divided into biodegradable and biodegradable absorbable. Among them, biodegradable and absorbable ones are of great significance to the repair and reconstruction of tissues and organs. It disappears by degrading into substances that can be absorbed by the human body, avoiding some adverse effects such as rejection in the body and non-infectious inflammation. Collagen, also known as collagen, is the most abun...

Claims

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Application Information

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IPC IPC(8): A61L17/10A61L17/06A61L17/14D01F1/10D01F8/02D01F8/18
Inventor 不公告发明人
Owner 钊桂英
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