Formula for treating nephrotic syndrome and preparation method

A technology of nephrotic syndrome and prescriptions, applied in the field of prescriptions for treating nephrotic syndrome and its preparation, can solve the problems of unsuitable long-term use, large toxic and side effects, and strong dependence, and achieve no adverse reactions, quick results, and safe use Effect

Inactive Publication Date: 2016-02-03
李连庆
4 Cites 3 Cited by

AI-Extracted Technical Summary

Problems solved by technology

[0004] Although Western medicine has good curative effect in treating nephrotic syndrome, it has a long course of treatment, strong dependence, high toxicity and side effects, and is not suitable for long-term use. Traditional Chinese medicine is relative...
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Abstract

The invention discloses a formula for treating a nephrotic syndrome. The formula is mainly prepared from, by mass, 9-14 parts of semen cuscutae, 6-10 parts of equisetum arvense, 8-12 parts of wideleaf osbeckia roots, 9-13 parts of phaseolus angularis, 5-10 parts of paniculate swallowwort roots, 9-15 parts of arundina graminifolia, 10-14 parts of corn stigma, 7-12 parts of vigna sesquipedalis, 8-13 parts of lespedeza bicolor, 4-9 parts of pericarpium arecae, 8-14 parts of procumbent urena roots, 9-12 parts of four-leaved clover, 7-13 parts of radermachera sinica and 6-9 parts of fructus rubi. Products prepared from the formula are all traditional Chinese medicine preparations and are stable in component, reliable in treatment effect, safe to administrate and free of dependency. The formula is developed according to the traditional Chinese medicine principle, has the effects of warming the kidney, strengthening the spleen, engendering body fluid and nourishing blood and is good in treatment effect, capable of rapidly achieving the effects, free of adverse effects and small in economic burden.

Application Domain

Urinary disorderPlant ingredients

Technology Topic

Radermachera sinicaBody fluid +16

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  • Formula for treating nephrotic syndrome and preparation method

Examples

  • Experimental program(5)
  • Effect test(1)

Example Embodiment

[0058] Example 1 The prescription for the treatment of nephrotic syndrome is mainly prepared from the following raw materials (10g each): 9 parts of Dodder, 6 parts of Chrysanthemum, 8 parts of Yangtianzhong, 9 parts of Chixiaodou, 5 parts of Xu Changqing, 9 parts of Bamboo Leaf Orchid, Corn 10 parts of mustard, 7 parts of cowpea, 8 parts of huzhizi, 6 parts of lychee grass, 4 parts of big belly, 8 parts of Brahma root, 9 parts of four-leaf clover, 7 parts of bean tree, 6 parts of raspberry.
[0059] The preparation method of the above-mentioned prescription decoction for the treatment of nephrotic syndrome is:
[0060] (1) Pour the sesame oil into a pot and heat it up, sprinkle with dodder seeds and red bean and stir-fry until there is a crackling sound, take it out, let it cool, add rice wine together with the raspberries and mix well, put it in a steamer, steam it thoroughly, take it out, drying;
[0061] (2) Take Xu Changqing and the big belly skin, wash them with salt water, cook them in boiling vinegar for 10 minutes, remove them, let them cool and cut into shreds, put them in a wok and heat them on low heat, fry them until yellow, take them out, and let them cool;
[0062] (3) Wash the Yangtian Bell, Bamboo Leaf Orchid, Huzhizi and Clover, add honey and water, mix well and simmer for 17.5 minutes, take it out and put it in a frying pan, heat it slowly and fry it until it doesn't stick to the hand, take it out and let it cool ;
[0063] (4) Wash the wattle, corn silk, cowpea, lychee grass, Brahma root and bean tree, soak in warm water for 20 minutes, take out, and boil with the raw materials prepared in step (2) (3), add the amount of water It is 6.5 times the quality of the raw material to be boiled. After boiling on high heat, fry it on low heat for 30 minutes, filter, add the filter residue to the raw material prepared in step (1), add water to boil (the amount of water added is 7 times the mass of the total raw material), and boil Then, simmer for 20 minutes, filter, combine the two filtrates, and sterilize to obtain the decoction.

Example Embodiment

[0064] Example 2 The prescription for the treatment of nephrotic syndrome is mainly prepared from the following raw materials (10g each): 14 parts of Dodder, 10 parts of Jingjing, 12 parts of Yangtianzhong, 13 parts of Chixiaodou, 10 parts of Xu Changqing, 15 parts of Bamboo Leaf Orchid, corn 14 parts of mustard, 12 parts of cowpea, 13 parts of mustache, 14 parts of lychee grass, 9 parts of big belly, 14 parts of Brahma root, 12 parts of four-leaf clover, 13 parts of kidney bean tree, 9 parts of raspberry.
[0065] The preparation method of prescription granules for treating nephrotic syndrome is:
[0066] (1) Pour the sesame oil into a pot and heat it up, sprinkle with dodder seeds and red bean and stir-fry, fry until there is a popping sound, take it out, let it cool, then mix it with raspberries and rice wine, put it in a steamer, steam it thoroughly, take it out, and bake it dried, crushed;
[0067] (2) Take Xu Changqing and the big belly skin, wash them with salt water, cook them in boiling vinegar for 10 minutes, remove them, let them cool and cut into shreds, put them in a wok and heat them on low heat, fry them until yellow, take them out, and let them cool;
[0068] (3) Wash the Yangtian Bell, Bamboo Leaf Orchid, Huzhizi and Clover, add honey and water, mix well and simmer for 17.5 minutes, take it out and put it in a frying pan, heat it slowly and fry it until it doesn't stick to the hand, take it out and let it cool ;
[0069] (4) Wash the wattle, corn silk, cowpea, lychee grass, Brahma root and bean tree, soak in warm water for 20 minutes, take out, and boil with the raw materials prepared in step (2) (3), add the amount of water It is 8 times the mass of the raw material to be boiled, boil it on high heat and then fry it on low heat for 30 minutes, filter, add water to the filter residue and cook again (the amount of water added is 7 times the quality of the raw material to be boiled), boil for 20 minutes on low heat, filter , the two filtrates were combined and concentrated into a clear paste;
[0070] (5) Mixing the pharmaceutical powder and clear paste obtained in step (1) and step (4), adding sucrose and starch slurry and mixing, making soft material, granulating, drying, granulating and sterilizing to obtain granules.
[0071] Typical case: xxx, female, 36 years old. Chief Complaint: I had a cold and cough two weeks ago, and the symptoms improved after taking the medicine, but the edema of the eyelids and limbs occurred in the past 3 days, hospital examination, moderate edema of the eyelids and limbs, backache, fatigue, poor appetite, red and yellow urine, low volume, Foamy, red tongue, thick coating, thin pulse, urine protein (+++), plasma albumin 24.2g/L, high blood lipids, diagnosis of primary nephrotic syndrome.
[0072] The prescription granules for the treatment of nephrotic syndrome obtained in this example were taken, 2 times a day, 4-6 g each time, mixed with warm boiled water, and a course of treatment was 30 days. After taking it for two weeks, the edema was slightly relieved, and the spirit was slightly improved. After taking one course of treatment, the edema subsided obviously, the backache and tiredness were basically eliminated, and the urine protein (++), after two courses of treatment, the patient's edema basically disappeared, and the appetite recovered as In the past, urine protein (-), plasma albumin 29.5g/L, normal urine, normal blood lipids, normal renal function, continued taking a course of treatment and then discontinued the drug, followed up one year later, and the condition was stable.

Example Embodiment

[0073] Example 3 The prescription for the treatment of nephrotic syndrome is mainly prepared from the following raw materials (10g each): 10 parts of Dodder, 7 parts of Chrysanthemum, 9 parts of Yangtianzhong, 10 parts of Chixiaodou, 6 parts of Xu Changqing, 11 parts of Bamboo Leaf Orchid, corn 11 parts of mustard, 8 parts of cowpea, 9 parts of huzhizi, 8 parts of lychee grass, 5 parts of big belly, 10 parts of Brahma root, 10 parts of four-leaf clover, 8 parts of bean tree, 7 parts of raspberry.
[0074] The preparation method of the prescription tablet for treating nephrotic syndrome is:
[0075] (1) Pour the sesame oil into a pot and heat it up, sprinkle with dodder seeds and red bean and stir-fry, fry until there is a popping sound, take it out, let it cool, then mix it with raspberries and rice wine, put it in a steamer, steam it thoroughly, take it out, and bake it dried, crushed;
[0076] (2) Take Xu Changqing and the big belly skin, wash them with salt water, cook them in boiling vinegar for 10 minutes, remove them, let them cool and cut into shreds, put them in a wok and heat them on low heat, fry them until yellow, take them out, and let them cool;
[0077] (3) Wash the Yangtian Bell, Bamboo Leaf Orchid, Huzhizi and Clover, add honey and water, mix well and simmer for 17.5 minutes, take it out and put it in a frying pan, heat it slowly and fry it until it doesn't stick to the hand, take it out and let it cool ;
[0078] (4) Wash the wattle, corn silk, cowpea, lychee grass, Brahma root and bean tree, soak in warm water for 20 minutes, take out, and boil with the raw materials prepared in step (2) (3), add the amount of water It is 8 times the mass of the raw material to be boiled, boil it on high heat and then fry it on low heat for 30 minutes, filter, add water to the filter residue and cook again (the amount of water added is 7 times the quality of the raw material to be boiled), boil for 20 minutes on low heat, filter , the two filtrates were combined and concentrated into a clear paste;
[0079] (5) Mixing the pharmaceutical powder and clear paste obtained in step (1) and step (4), drying, pulverizing, and preparing a pharmaceutical powder, and pressing the pharmaceutical powder into a round or other form of tablet according to the processing and preparation method of the tablet. Form dosage form, the content of Chinese medicinal powder in the tablet is 0.35g/tablet, and sterilized to obtain tablet.
[0080]Typical case: xxx, male, 56 years old. Eyelid and lower extremities edema, fatigue and fatigue, accompanied by nausea, anorexia, hospital examination, yellow urine, small amount, red tongue, thin white coating, thin and slippery pulse, plasma albumin 26.4g/ L, urine protein (++), total cholesterol 10.4mmol/L, triglyceride 2.74mmol/L, diagnosis of nephrotic syndrome.
[0081] Taking the prescription tablets for the treatment of nephrotic syndrome obtained in the present example, 2 times a day, 3 tablets each time, with warm boiled water, and a course of treatment for 30 days. After taking half a course of treatment, the appetite increased and the spirit improved. After taking one course of treatment, the color of urine became lighter, the edema was significantly reduced, and the nausea was eliminated. After taking two courses of treatment, the edema completely subsided, and other discomfort symptoms also disappeared. After taking three courses of treatment , Review urine protein (-), plasma albumin 30.7g/L, total cholesterol 5.2mmol/L, triglyceride 1.85mmol/L, normal renal function, the patient recovered, and there was no recurrence after one-year follow-up.

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