Rabdosia amethystoides slowly released drop pill with effect of eliminating stasis to subdue swelling

Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a rabdosia amethystoides slowly released drop pill with effect of eliminating stasis to subdue swelling and a preparation method thereof. The rabdosia amethystoides slowly released drop pill consists of the following components in percentage by weight: 20%-40% of rabdosia amethystoides extracts, 40%-60% of hydrophilic framework materials, and 20-%-30% of hydrophobic framework materials; the hydrophilic framework materials are a mixture of one or more than two of polyethylene glycol 1,500, polyethylene glycol 4,000, polyethylene glycol 6,000, polyvinylpyrrolidone and microcrystalline cellulose; and the hydrophobic framework materials are a mixture of one or more than two of stearic acid, Brazil palmatic acid, glycerin monostearate and stearyl alcohol. The rabdosia amethystoides slowly released drop pill has the advantages of high bioavailability, quick effectiveness, long drug release time, less medicine taking frequency, low toxic and side effects, high drug content, small administration dose, accurate administration dose, convenience in administration, low price and convenience in carrying when a patient goes out.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a fragrant tea vegetable sustained-release dripping pill for dispelling blood stasis and reducing swelling and a preparation method thereof. Background technique [0002] At present, for patients with swelling and pain in the body, a drug with a long and rapid effect is needed. Due to reasons such as preparation technology, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, all exist after taking. Problems such as long dissolution time, low dissolution rate, poor absorption, unstable blood drug concentration, insufficient drug release, frequent medication times, hepatic and intestinal first-pass effect and low bioavailability affect the efficacy of the drug. It also directly affects the treatment effect. [0003] In addition, conventional oral dosage forms, such as tablets, capsules, etc., wil...

AI Technical Summary

Problems solved by technology

[0002] At present, for patients with swelling and pain in the body, a drug with a long and rapid effect is needed. Due to reasons such as preparation technology, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, all exist after taking. Problems such as long dissolution time, low dissolution rate, poor absorption, unstable blood drug concentration, insufficient drug release, frequent medication times, hepatic and intestinal first-pass effect and low bioavailability affect the efficacy of the drug. It also directly affects the therapeutic effect

[0003] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment

Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.