Medical adhesives and preparation method thereof
A technology of adhesive and sodium alginate, which is applied in chemical modification and medical fields, can solve problems such as insufficient elasticity of organ surface tension, inapplicable tissue bonding, secondary risk of patients, etc., achieve shortened gel time, and the preparation method Convenience, Inexpensive Effects
Active Publication Date: 2016-02-17
莫秀梅 +1
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The invention relates to medical adhesives and a preparation method thereof. The adhesives are prepared from aldehyde sodium alginate and amination carboxymethyl chitosan. The preparation method includes the steps of mixing equal volumes of aldehyde sodium alginate solution with concentration of 10-50 wt% and amination carboxymethyl chitosan solution with concentration of 1-6 wt%, conducting a Schiff base reaction to form hydrogel, and obtaining the medical adhesives. Selected aldehyde sodium alginate and amination carboxymethyl chitosan are both natural biological materials, are free of toxin and odor, quite high in biological compatibility, low in price, safe, reliable, capable of being locally sprayed or injected to any part of a body in situ and low in cost, and is ideal substitute goods for fibrin glue sold on the market. The preparation method is simple.
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Property | Measurement | Unit |
Viscosity | 580.0 | mPa·s |
tensile | MPa | |
Particle size | Pa | |
strength | 10 |
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