11results about How to "Short gel time" patented technology

The invention discloses a preparation method of a low-cost high-temperature-resistant silicon oxide aerogel composite material, which selects high-quality and low-cost inorganic silica sol as a silicon source, is doped with a functional additive and is compounded with a fiber reinforced material, so that the problems of high silicon source cost, poor high-temperature resistance, low strength, poor flame retardance and the like of the silicon oxide aerogel material are solved. Meanwhile, the material has certain flexibility and is convenient to construct.

The invention provides an anti-HPV (human papillomavirus) temperature-sensitive gel as well as a preparation method and application thereof. The invention provides the anti-HPV temperature-sensitive gel as well as the preparation method and application thereof. The gel consists of a natural active extract, a temperature-sensitive polymer, a cross-linking agent and a stabilizer, wherein the natural active extract comprises a mixture of a sophora flavescens extract, an artemisia annua extract and a mushroom extract in a specific mass ratio. These extracts are obtained by specific extraction processes to ensure their antiviral activity. The thermo-sensitive polymer is a mixture of poly (N-isopropylacrylamide) and hydroxypropyl methyl cellulose, and the cross-linking agent and the stabilizer are used for enhancing the performance of the gel. The preparation method of the gel comprises the following steps: preparing a natural active extract emulsion, preparing a wall material solution, emulsifying and microencapsulating, so as to finally form the gel with temperature sensitivity. The gel has specific rheological properties at body temperature, can be used for treating HPV infection, and provides a new local treatment method.

The present invention proposes a fat stem cell composition for wound repair and a preparation method and application thereof, which belongs to the field of stem cell technology. Fetal bovine serum, dexamethasone, penicillin, streptomycin, collagen, magnetic particles, and substance P are added to DMEM culture medium to prepare a culture medium for low-frequency magnetic field culture of fat mesenchymal stem cells, separation, obtaining a stem cell solution, embedding to obtain stem cell microspheres, freeze-drying the supernatant to obtain paracrine culture material, and mixing with stem cell microspheres, hydroxypropyl methylcellulose, carboxymethyl chitosan, hyaluronic acid, glycerol, and stem cell microspheres to obtain a fat stem cell composition for wound repair, which has good effects of implanting damaged tissues, releasing nutrients, promoting new blood vessel formation, regulating oxidative stress and inducing anti-inflammatory reactions, and is helpful for wound repair. It can be converted into a gel phase at a skin epidermal temperature between 35-37°C, stabilizes components, and releases in a controlled manner.

The invention discloses an injectable dura mater sealant with adjustable mechanical properties as well as a preparation method and application thereof. The dura mater sealant comprises the following components in percentage by mass: 75-95% of a polymer; 1-20% of modified nano cellulose; 1-5% of an antibacterial agent; 0.1 to 0.5 percent of analgesic medicine; and a color marker is 0.01 to 0.05 percent. The dura mater sealant can form gel in a short time through rapid reaction between polymers; the protein in the tissue quickly reacts with the polymer, so that the dura mater sealant can be instantly adhered to the surface of the tissue and has high adhesion; due to the addition of the modified nanocellulose, the prepared dura mater sealant has adjustable and relatively high mechanical strength, and leakage of cerebrospinal fluid can be effectively prevented. The prepared dura mater sealant has the advantages of being short in gelation time, adjustable in mechanical property, high in adhesion and the like, and has a good application prospect in dura mater sutureless sealing.

The invention discloses polyacrylamide gel, the gel comprises concentrated gel and separation gel, and a gel solution of the concentrated gel comprises a polyacrylamide concentrated gel premixed solution and an initiator; a gel solution of the separation gel comprises a polyacrylamide separation gel premixed solution and an initiator; the polyacrylamide concentrated gel premix solution comprises 4 wt% of a polyacrylamide solution, a Tris-HCl buffer solution, 0.4 wt% of a coagulant and a dye; the polyacrylamide separation gel premix solution comprises 6 wt%-15 wt% of a polyacrylamide solution, a Tris-HCl buffer solution and 1.2 wt% of a coagulant; the coagulant comprises N, N, N ', N'-tetraethylethylenediamine and sodium hydrogen sulfite; the initiator comprises ammonium persulfate. By improving the components and proportion of the coagulant, the gelation time is shortened, and the harm of toxic reagent volatilization to people in the gel preparation process is reduced; meanwhile, by adding a certain proportion of halogenated acetic acid, the observation convenience and the experiment efficiency are improved.

The present application relates to the technical fields of epoxy resin synthesis, in particular to a phenolic epoxy resin, a preparation method and application thereof. The phenolic epoxy resin has the structure shown in the following formula I: Formula I; wherein, in the formula I, n represents a polymerization degree, and is 0.2-0.6; R1, R2 and R3 are each independently selected from H or C1-C 10 alkyl; and R4 is selected from H or a fused ring group. The preparation method of the phenolic epoxy resin adds a phenolic compound for molecular modification in a refining stage, increases the proportion of secondary hydroxyl groups in the epoxy resin, promotes the curing of the epoxy resin, effectively shortens the gel time of the epoxy resin, does not change the mechanical properties of the cured epoxy resin, avoids adding a small molecule accelerator in the epoxy resin compound, and therefore can effectively improve the electrical properties of the cured product.

The invention provides mixed calcium-increasing thermally-activated loess, a preparation method and application thereof, a modified loess cement-based cementing material and application thereof, and a modified loess cement-based cementing hydrated material and application thereof, and relates to the technical field of coal mine grouting and water-retention mining. The preparation method comprises the following steps: mixing loess with a calcium-increasing agent, and calcining to obtain mixed calcium-increasing heat-activated loess; the calcium increasing agent comprises dolomite and soda ash; the mass ratio of the loess to the calcium increasing agent is (1.5-2.5): 1; the calcination temperature ranges from 1000 DEG C to 1100 DEG C. The dolomite and the soda ash are utilized to perform calcium-increasing modification on the loess, and the calcining temperature and the use amount of the calcium-increasing agent are controlled, so that the pozzolanic activity of the loess is greatly improved, and the hydration reaction activity when the modified loess is used for preparing the cement-based grouting material is further improved. The mixed calcium-increasing heat-activated loess provided by the invention has a good application prospect in water-retaining grouting mining of mines.

The invention relates to a nano SiO2 / CTPBA / EP high-toughness adhesive which comprises a CTPBA / EP resin matrix and nano SiO2 which is modified by a silane coupling agent and mixed in the CTPBA / EP resin matrix. The invention relates to a nano SiO2 / CTPBA / EP high-toughness adhesive which is applied to seawater pipeline repair. The preparation method has the beneficial effects that the flexible chain segment carboxyl-terminated polyester CTPBA and the modified nano SiO2 synergistically carry out toughening modification on the epoxy resin, so that the characteristic that the tensile strength and the heat resistance of the epoxy resin are easily lost due to modification of the flexible chain segment is avoided, the nano SiO2 is modified by using the silane coupling agent KH550, the dispersity of the nano SiO2 in a resin matrix is effectively improved, and the tensile strength and the heat resistance of the epoxy resin are effectively improved. The interaction between the nano SiO2 and a resin matrix is enhanced, and the mechanical property, the adhesive property, the thermodynamic property, the moisture resistance and the like of the epoxy resin composite material are obviously improved.

The present invention belongs to the technical field of medical materials, and relates to a sol-gel preparation method and product of 45S5 bioactive glass. The preparation method comprises the following steps: (1) synthesis of phosphoric acid-ethylene glycol ester; (2) preparation of nitrogen-containing carbon quantum dots; (3) preparation of sol; (4) preparation of aqueous solution; (5) preparation of gel; and (6) heat treatment. The present invention also provides a 45S5 bioactive glass. In the sol-gel preparation method of the present invention, phosphoric acid-ethylene glycol ester is used as the source of P2O5 in the product, which can avoid the problem of difficult control of product phosphorus content and waste of raw materials caused by volatilization when triethyl phosphate is used as a raw material in the prior art. At the same time, nitrogen-containing carbon quantum dots are used, so that the specific surface area of ​​the prepared 45S5 bioactive glass is effectively improved. The present invention has the advantages of safe raw materials, short required gel time, stable oxide components in the product, and high specific surface area of ​​the prepared 45S5 bioactive glass.

The invention discloses a curing agent with adjustable reaction activity, a high-modulus epoxy resin matrix and a preparation method of the high-modulus epoxy resin matrix. The adjustable curing activity epoxy resin matrix disclosed by the invention has the characteristics of high strength and high modulus, and is a combination of polyfunctionality epoxy resin and a novel activity adjustable aromatic amine curing agent; the novel activity-adjustable aromatic amine curing agent is a compound obtained after amino and an electron-withdrawing group or an electron-donating group replace aromatic ring structures such as a benzene ring, biphenyl, diphenyl and a fused ring, and on the basis that the high modulus and other mechanical properties of the epoxy resin can be guaranteed, the curing activity of the resin can be regulated and controlled within a large range; therefore, the actual requirements of different composite material forming processes are met.

The invention provides a preparation process and a preparation system of a wet glass fiber aerogel product, and relates to the technical field of new energy automobiles, the preparation process of the wet glass fiber aerogel product comprises the following steps: preparing a glue solution; the prepared glue solution enters a glue dipping tank, the sheet-shaped wet glass fiber felt is fully dipped in the glue solution in the tank, and then the sheet-shaped wet glass fiber felt is placed on a belt and enters a microwave section for gel forming; putting the prepared product into a product basket, and then putting the product basket into an aging tank for aging-modification; and after aging-modification is completed, directly taking out the product basket in the aging tank, putting the product basket into a supercritical drying tank, and carrying out supercritical drying on the product. Through a continuous microwave forming production mode, the product gelation time is greatly shortened, the production efficiency is improved, due to the fact that product gelation is accelerated through microwave heating, it can be guaranteed that the product gel surface is uniform, the product gelation time is greatly shortened, the production efficiency is improved, and the product quality is guaranteed.