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Preparation method of donkey-hide gelatin oral solution with function of life prolongation

A technology of oral liquid and donkey-hide gelatin, which is applied in the field of preparation of donkey-hide gelatin Yishou oral liquid, can solve the problems of high viscosity of extract, lower drug efficacy, and adhesion of extract, so as to reduce viscosity, reduce adhesion amount, and improve utilization rate Effect

Active Publication Date: 2016-03-23
SICHUAN XUYANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, usually the water extract is directly concentrated, because the sugars and cellulose substances in the crude drug enter the extract, the viscosity of the extract is relatively high after concentration, causing the extract to adhere to the wall of the extraction tank without easy to get
Moreover, in the process of refining the extract, the use of pure water for dissolving often causes part of the extract to be incompletely dissolved or has low solubility, causing some effective substances to be filtered out along with the residue, thereby reducing the efficacy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The prescription of Ejiao Yishou Oral Liquid is:

[0030] Ginseng 30.48kg, honey-made Astragalus 304.8kg, Rehmannia glutinosa 152.4kg, Polygonum multiflorum 152.4kg;

[0031] Ejiao 76.2kg, Chenpi 60.96kg, Muxiang 30.48kg, Licorice 30.48kg,

[0032] Sucrose 120kg, sodium benzoate 6kg.

[0033] Preparation steps:

[0034] Extraction: Put ginseng, dried tangerine peel, licorice, woody incense, roasted astragalus, rehmannia glutinosa, and made Polygonum multiflorum into the multi-functional extraction tank according to the principle of equal distribution, add 6 times of the total amount of medicinal materials for the first time and boil for 120min. Add 5 times the total amount of pure water for the second time, boil for 120 minutes, add 5 times the total amount of pure water for the third time, and boil for 60 minutes. The steam pressure of the heating control jacket is 0.20Mpa; the micro-boiling temperature is controlled at 100 ℃, and the micro-boiling is maintained unt...

Embodiment 2

[0048] The prescription of Ejiao Yishou Oral Liquid is:

[0049] Ginseng 30.48kg, honey-made Astragalus 304.8kg, Rehmannia glutinosa 152.4kg, Polygonum multiflorum 152.4kg;

[0050] Ejiao 76.2kg, Chenpi 60.96kg, Muxiang 30.48kg, Licorice 30.48kg,

[0051] Sucrose 120kg, sodium benzoate 6kg.

[0052] Preparation steps:

[0053] Extraction: Put ginseng, dried tangerine peel, licorice, woody incense, roasted astragalus, rehmannia glutinosa, and made Polygonum multiflorum into the multi-functional extraction tank according to the principle of equal distribution, add 6 times of the total amount of medicinal materials for the first time and boil for 120min. Add 5 times the total amount of pure water for the second time, boil for 120 minutes, add 5 times the total amount of pure water for the third time, and boil for 60 minutes. The steam pressure of the heating control jacket is 0.20Mpa; the micro-boiling temperature is controlled at 100 ℃, and the micro-boiling is maintained unt...

Embodiment 3

[0057] The prescription of Ejiao Yishou Oral Liquid is:

[0058] Ginseng 30.48kg, honey-made Astragalus 304.8kg, Rehmannia glutinosa 152.4kg, Polygonum multiflorum 152.4kg;

[0059] Ejiao 76.2kg, Chenpi 60.96kg, Muxiang 30.48kg, Licorice 30.48kg,

[0060] Sucrose 120kg, sodium benzoate 6kg.

[0061] Preparation steps:

[0062] Extraction: Put ginseng, dried tangerine peel, licorice, woody incense, roasted astragalus, rehmannia glutinosa, and prepared Polygonum multiflorum into the multi-functional extraction tank according to the principle of equal distribution. For the first time, add 6 times the total amount of medicinal materials with pure water and the quality of pure water. 6% ethanol and 1% potassium sorbate were boiled for 120min, and the pH was controlled to 6.8. For the second time, pure water 5 times the total amount of medicinal materials, 7% pure water quality ethanol and 1.5% potassium sorbate were added, and boiled for 120min. Add pure water 5 times the total ...

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Abstract

The invention discloses a preparation method of a donkey-hide gelatin oral solution with a function of life prolongation. The preparation method comprises repeated boiling extraction of seven crude drugs, an extracting solution is concentrated through a triple-effect concentrator, a double-effect concentrator and a single-effect concentrator respectively, concentrated extract is refined in pure water, a donkey-hide gelatin solution and syrup are prepared, and material preparation is completed. According to the method, the water extracting solution is divided into three parts and sequentially concentrated through the triple-effect concentrator, the double-effect concentrator and the single-effect concentrator respectively, and the viscosity of the concentrated extract is reduced through sectional concentration of the extracting solution. Meanwhile, the water precipitation step of the extract is further optimized, so that effective ingredients in the extract are better dissolved in and dissolved out of water, and the utilization rate of the effective ingredients is increased.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction and preparation, in particular to a preparation method of Ejiao Yishou oral liquid. Background technique [0002] Ejiao Yishou Oral Liquid to nourish qi and nourish blood is used for both deficiency of qi and blood, weakness of limbs, soreness and weakness of waist and knees, yellow face and thin muscles, forgetfulness and insomnia, and postpartum deficiency in women. Postpartum deficiency in women is a common and frequent disease in clinical practice, which seriously affects people's daily life. At present, there are many Chinese patent medicines for the treatment of this disease, but these varieties all have defects such as less than ideal curative effect. Prior art: Ejiao Yishou Oral Liquid is a pure traditional Chinese medicine preparation under the sixth volume WS3-B-1143-92 of the ministry standard "Prescriptions of Traditional Chinese Medicine". The traditio...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K36/804A61P1/14A61P39/00A61K35/36
CPCA61K9/0053A61K9/08A61K35/36A61K36/258A61K36/285A61K36/481A61K36/484A61K36/704A61K36/752A61K36/804A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 韩业祥侯嘉
Owner SICHUAN XUYANG PHARMA
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