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Pharmaceutical preparation containing argy wormwood leaves and having bowel relaxing function as well as preparation method of pharmaceutical preparation

A kind of medicine preparation, the technology of moistening bowel and laxative

Inactive Publication Date: 2016-03-23
叶宗耀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term abuse of stimulant laxatives not only causes intractability and complexity of constipation, but also can cause laxative colon, intestinal black lesions, etc.
[0005] Chinese patent application 201410580616.0 discloses a traditional Chinese medicine for relaxing bowels and laxatives, which is prepared from hemp seed, rhubarb, raw Shouwu, cistanche, loquat leaf, croton, polyporus, lentil, Atractylodes macrocephala and licorice in a certain weight ratio This medicine has the effect of moistening the intestines and laxative. However, Shouwu and Croton are both Chinese herbal medicines with obvious toxicity. Long-term use can easily cause damage to the human liver and digestive system. This traditional Chinese medicine has serious side effects and is not suitable for long-term use

Method used

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  • Pharmaceutical preparation containing argy wormwood leaves and having bowel relaxing function as well as preparation method of pharmaceutical preparation
  • Pharmaceutical preparation containing argy wormwood leaves and having bowel relaxing function as well as preparation method of pharmaceutical preparation
  • Pharmaceutical preparation containing argy wormwood leaves and having bowel relaxing function as well as preparation method of pharmaceutical preparation

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Experimental program
Comparison scheme
Effect test

Embodiment l

[0037] Example 1 of the present invention contains the laxative medicinal preparation of mugwort leaf prepared from the following raw materials in parts by weight:

[0038] 10 parts of mugwort leaves, 10 parts of cistanche, 8 parts of cassia seeds, 8 parts of konjac, 8 parts of peach kernels, 6 parts of Niu Xixi, 6 parts of poria cocos, 6 parts of angelica, 4 parts of hemp seeds, 4 parts of linseed and 4 parts of licorice.

[0039] Preparation:

[0040] S1: Weigh each medicinal material according to the proportion, wash away the impurities, grind them separately after drying, pass through an 80-mesh sieve, and set aside;

[0041] S2: Take Artemisia argyi leaf coarse powder, place it in a supercritical carbon dioxide extraction device, add ethanol with a volume fraction of 45% of the total amount of coarse powder and 75% ethanol, adjust the flow rate of carbon dioxide to 20L / h, the extraction pressure to 20MPa, and the extraction temperature to 60°C. The extraction time is 3 h...

Embodiment 2

[0047] Example 2 of the present invention contains the laxative medicinal preparation of mugwort leaf prepared from the following raw materials in parts by weight:

[0048] 22 parts of mugwort leaf, 20 parts of cistanche, 20 parts of cassia seed, 18 parts of konjac, 16 parts of peach kernel, 16 parts of Niu Xixi, 18 parts of poria cocos, 16 parts of angelica, 14 parts of hemp seed, 16 parts of linseed and 10 parts of licorice.

[0049] Preparation method: with embodiment 1.

Embodiment 3

[0051] Example 3 of the present invention contains the medicinal preparation of laxatives containing leaves of mugwort prepared from the following raw materials in parts by weight:

[0052] 16 parts of mugwort leaf, 14 parts of cistanche, 14 parts of cassia seed, 12 parts of konjac, 12 parts of peach kernel, 10 parts of Niu Xixi, 12 parts of poria cocos, 10 parts of angelica, 9 parts of hemp seed, 10 parts of flaxseed and 7 parts of licorice.

[0053] Preparation method: with embodiment 1.

[0054] Pharmacodynamic experiment

[0055] Test one, the influence of pharmaceutical preparation of the present invention on normal mouse defecation

[0056] 1. Experimental method

[0057] 1.1 Experimental animals and grouping

[0058] Get 110 SPF level ICR mice, half male and half male, randomly divided into normal control group, positive control group, pharmaceutical preparation A, B and C groups of the present invention, wherein A, B and C groups are further divided into high, middl...

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Abstract

The invention belongs to the field of traditional Chinese medicines and relates to a pharmaceutical preparation containing argy wormwood leaves and having a bowel relaxing function as well as a preparation method of the pharmaceutical preparation. The pharmaceutical preparation is prepared from raw materials in parts by weight as follows: 10-22 parts of the argy wormwood leaves, 10-20 parts of Boschniakia rossia, 8-20 parts of cassia seeds, 8-18 parts of konjak, 8-16 parts of peach seeds, 6-16 parts of patience dock roots, 6-18 parts of Poria cocos, 6-16 parts of Chinese angelica, 4-14 parts of hemp seeds, 4-16 parts of linseeds and 4-10 parts of liquorice roots. All components of the pharmaceutical preparation are purely natural Chinese herbal medicines, and the pharmaceutical preparation has functions of clearing heat, brightening the eyes, relaxing the bowel, tonifying the spleen and calming nerves and has the significant curative effect on dry stool, constipation due to blood deficiency as well as constipation due to yin deficiency and intestinal dryness.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a medicinal preparation containing mugwort leaves for soothing bowel movements and a preparation method thereof. Background technique [0002] Constipation is a common clinical symptom. It mainly refers to the decrease in the frequency of defecation, the decrease in the amount of feces, the dryness of feces, and the difficulty of defecation. When two or more of the above symptoms are present at the same time, it can be diagnosed as symptomatic constipation. Usually, the frequency of defecation is reduced. Generally, one bowel movement every 2-3 days or longer is considered constipation. Some patients with constipation have bitter mouth, loss of appetite, abdominal distension, lower abdominal discomfort, excessive exhaust, or neurological symptoms such as dizziness, headache, and fatigue, but they are generally not severe. Due to the high incidence of co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P1/10
CPCA61K36/888A61K36/076A61K36/232A61K36/282A61K36/482A61K36/484A61K36/55A61K36/60A61K36/64A61K36/70A61K36/736A61K2236/331A61K2236/37A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 叶宗耀邹锦新
Owner 叶宗耀