Preparation method and application of royal jelly and bee pollen composition
A technology for bee pollen and royal jelly, which is applied in the directions of application, drug combination, non-active ingredients of polymer compounds, etc.
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Embodiment 1
[0029] Example 1 Cyclodextrin Taste-Masked and Included Royal Jelly Freeze-dried Powder
[0030] The taste-masking freeze-dried powder of royal jelly consists of:
[0031] Royal Jelly 300g
[0032] Hydroxypropyl-β-cyclodextrin 100g
[0033] Purified water 300g
[0034] The preparation method is as follows:
[0035] (1) Dissolve 100g of hydroxypropyl-β-cyclodextrin into 300g of purified water, add 300g of royal jelly powder under stirring conditions, and continue stirring for 36 hours after stirring;
[0036] (2), put the above liquid into the freeze dryer, freeze dry to below 2.0% moisture;
[0037] (3), the finished product is taken out, pulverized, sieved, and set aside.
[0038] The freeze-dried powder has a good mouthfeel and basically no sour, astringent, spicy and other bad tastes.
Embodiment 2
[0039] Example 2 Preparation of bee pollen extract
[0040] The preparation method of bee pollen extract is as follows:
[0041] (1) The bee pollen is crushed, passed through a 100-mesh sieve, and the wall of the bee pollen is broken by airflow crushing.
[0042] (2) Add 10 times the amount of bee pollen to 80% ethanol solution, soak for 2 hours under stirring at 40°C, centrifuge with a tubular centrifuge, and recover the filtrate under reduced pressure until it has no alcohol smell, which is solution 1;
[0043] (3) Add 10 times the amount of purified water to the residue, soak for several hours under stirring at 40°C, and centrifuge with a tubular centrifuge; the filtrate is solution 2;
[0044] (4) Combine solution 1 and solution 2, and freeze-dry until the water content is below 2.0%;
[0045] (5) The finished product is taken out, crushed, sieved, and set aside. The total polyphenol content in the extract is 4.53%, the total flavonoid content is 4.28%, and the total po...
Embodiment 3
[0046] Embodiment 3 royal jelly, bee pollen combination buccal tablet
[0047] The taste-masking freeze-dried lozenges of royal jelly consist of:
[0048]
[0049] The preparation method is as follows:
[0050] (1) Take 350 g of royal jelly taste-masked freeze-dried powder, 150 g of bee pollen extract, add 100 g of mannitol, and mix for 20 minutes.
[0051] (2) Add 90% ethanol to the evenly mixed powder, mix for 10 minutes, knead into a ball by hand, and then disperse after light pressing to make a soft material, granulate with a 24-mesh sieve, and dry at 40°C for 3 hours.
[0052](3) The dried granules are sized with a 24-mesh sieve, then magnesium stearate is added, mixed for 10 minutes, and the tablet is pressed with a Φ12*6mm shallow concave capsule punching die to make 1000 tablets.
[0053] (4) Full inspection, bottling, and storage.
[0054] The freeze-dried buccal tablet prepared by the method has delicate taste, smooth and beautiful surface, consistent color, lo...
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