Traditional Chinese medicine composition for treating child myasthenia gravis

A technology for myasthenia gravis and composition, which is applied in the direction of drug combination, drug delivery, and pharmaceutical formulation, which can solve the problems of high cost, narrow application range, and low practical value, and achieve simple preparation process, low production cost, and abundant sources Effect

Active Publication Date: 2016-05-04
乞国艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgical methods such as thymectomy and radiotherapy have unsatisfactory curative effects on the one hand, and the effect of more than five years remains to be seen; on the other hand, surgical methods can only be used for patients with myasthenia gravis with symptoms such

Method used

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  • Traditional Chinese medicine composition for treating child myasthenia gravis

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The preparation of embodiment 1 Chinese medicine composition

[0032] 1. Accurately weigh the following Chinese medicine raw materials: 10 parts of Astragalus, 10 parts of Codonopsis, 10 parts of Atractylodes macrocephala, 5 parts of Bupleurum, 5 parts of Cimicifuga, 5 parts of Angelica, 5 parts of Cornus, 5 parts of Morinda officinalis, and 5 parts of Cuscuta , 8 parts of yam, 6 parts of Shouwu, 5 parts of Caulis Spatholobus, 5 parts of wolfberry, 3 parts of licorice, 3 parts of tangerine peel, and 3 parts of Ophiopogon japonicus.

[0033] 2. Grinding and mixing the above-mentioned traditional Chinese medicine raw materials evenly.

Embodiment 2

[0034] The preparation of embodiment 2 Chinese medicine composition

[0035] 1. Accurately weigh the following Chinese medicine raw materials: 120 parts of astragalus, 30 parts of Codonopsis, 20 parts of Atractylodes macrocephala, 8 parts of Bupleurum, 8 parts of cohosh, 10 parts of angelica, 10 parts of cornus, 10 parts of Morinda officinalis, and 10 parts of dodder , 24 parts of yam, 30 parts of Shouwu, 12 parts of Caulis Spatholobus, 12 parts of wolfberry, 6 parts of licorice, 6 parts of tangerine peel, and 10 parts of Ophiopogon japonicus.

[0036] 2. The above-mentioned raw materials of traditional Chinese medicine are decocted twice with five times the amount of water, each time for two hours. Filtrate the combined filtrate, let it stand for 48 hours, then take the supernatant and concentrate it under reduced pressure to form a clear paste, then pulverize it into a fine powder, or concentrate under reduced pressure to form a thick paste.

Embodiment 3

[0037] The preparation of embodiment 3 Chinese medicine composition

[0038] 1. Accurately weigh the following Chinese medicine raw materials: 60 parts of Astragalus, 20 parts of Codonopsis, 15 parts of Atractylodes macrocephala, 6 parts of Bupleurum, 6 parts of Cimicifuga, 7 parts of Angelica, 7 parts of Cornus, 7 parts of Morinda officinalis, and 7 parts of Cuscuta , 16 parts of yam, 18 parts of Shouwu, 8 parts of Caulis Spatholobus, 8 parts of wolfberry, 5 parts of licorice, 4 parts of tangerine peel, and 6 parts of Ophiopogon japonicus.

[0039] 2. The above-mentioned traditional Chinese medicine raw material is refluxed three times with 85% ethanol of three times the amount, each time for one hour. Combine the filtrates, concentrate under reduced pressure to form a clear paste, and then pulverize into a fine powder, or concentrate under reduced pressure to form a thick paste.

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Abstract

The invention discloses traditional Chinese medicine composition for treating child myasthenia gravis. The traditional Chinese medicine composition is prepared from Chinese herbal raw materials in parts by weight as follows: 10-120 parts of membranous milkvetch roots, 10-30 parts of pilose asiabell roots, 10-20 parts of largehead atractylodes rhizomes, 5-8 parts of Chinese thorowax roots, 5-8 parts of largetrifoliolious bugbane rhizomes, 5-10 parts of Chinese angelica, 5-10 parts of common macrocarpium fruits, 5-10 parts of medicinal indianmulberry roots, 5-10 parts of south dodder seeds, 8-24 parts of Chinese yams, 6-30 parts of prepared tuber fleeceflower roots, 5-12 parts of suberect spatholobus stems, 5-12 parts of fructus lycii, 3-6 parts of liquorice, 3-6 parts of tangerine peel and 3-10 parts of dwarf lilyturf tubers. The traditional Chinese medicine composition is reasonably prepared, does not have toxic or side effects, is convenient to process, low in cost and suitable for popularization and use in clinic and has a remarkable treatment effect on child myasthenia gravis.

Description

technical field [0001] The invention belongs to the field of medicines and relates to a traditional Chinese medicine composition for treating children with myasthenia gravis. Background technique [0002] Myasthenia gravis is one of the intractable diseases of the nervous system. Its symptoms are: unilateral or bilateral eyelid drooping, weakness of limbs, difficulty swallowing and slurred speech. [0003] Traditionally, people use anticholinesterase drugs, thymectomy, and radiation therapy to treat myasthenia gravis, but anticholinesterase drugs such as neostigmine and pyridostigmine are temporary and locally effective. The drugs can only temporarily delay the onset of the disease, but long-term use will lead to the destruction of acetylcholine receptors in the human body, making the disease more serious. There are also many reports of severe side effects of anticholinesterase drugs used in medical applications. Surgical methods such as thymectomy and radiotherapy have un...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P21/04
CPCA61K9/0053A61K9/0095A61K9/08A61K9/1652A61K9/2059A61K9/4866A61K36/232A61K36/233A61K36/284A61K36/344A61K36/39A61K36/40A61K36/481A61K36/484A61K36/486A61K36/704A61K36/71A61K36/746A61K36/752A61K36/815A61K36/8945A61K36/8968A61K47/26A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 乞国艳
Owner 乞国艳
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