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New medical material

A new material and raw material technology, applied in application, medical science, surgery, etc., can solve the problems of poor impact resistance, slow degradation rate, insufficient bonding strength, etc., to improve impact resistance, moderate curing speed, and easy degradation. Effect

Inactive Publication Date: 2016-05-04
FOSHAN MINGQIAN TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The existing medical glue has the disadvantages of poor impact resistance, slow degradation speed, and insufficient bonding strength

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1 A new medical material, prepared from the following raw materials in parts by mass: 150 parts of butyl cyanoacrylate, 0.1 part of hydroquinone, 8 parts of aloe vera nanopowder, 55 parts of soybean protein powder, 44 parts of chitosan, 5 parts of acetic acid, 16 parts of polyvinyl alcohol; The preparation method is:

[0012] (1) Take fresh aloe vera, dry it to a moisture content of 15%, and crush it to a particle size of 300-500nm;

[0013] (2) Take each raw material according to the ratio, prepare a chitosan solution with a concentration of 30% in deionized water, then add deionized water 4 times the volume of the chitosan solution, heat to 50°C, add butyl cyanoacrylate, poly Vinyl alcohol, hydroquinone, soybean protein powder, and aloe vera nanopowder are mixed and stirred evenly, and the solid content is adjusted to 25%.

Embodiment 2

[0014] Embodiment 2 A new medical material, prepared from the following raw materials in parts by mass: 100 parts of butyl cyanoacrylate, 0.051 parts of hydroquinone, 24 parts of aloe vera nanopowder, 20 parts of soybean protein powder, 10 parts of chitosan, 1 part of acetic acid, 8 parts of polyvinyl alcohol; the preparation method is:

[0015] (1) Take fresh aloe vera, dry it to a moisture content of 20%, and crush it to a particle size of 300-500nm;

[0016] (2) Take each raw material according to the ratio, prepare a chitosan solution with a concentration of 40% in deionized water, then add deionized water three times the volume of the chitosan solution, heat to 60°C, add butyl cyanoacrylate, poly Vinyl alcohol, hydroquinone, soybean protein powder, and aloe vera nano-powder are mixed and stirred evenly, and the solid content is adjusted to 30%.

Embodiment 3

[0017] Embodiment 3 A new medical material, prepared from the following raw materials in parts by mass: 80 parts of butyl cyanoacrylate, 0.01 part of hydroquinone, 22 parts of aloe vera nanopowder, 35 parts of soybean protein powder, 30 parts of chitosan, 3 parts of acetic acid, 18 parts of polyvinyl alcohol; the preparation method is:

[0018] (1) Take fresh aloe vera, dry it to a moisture content of 10%, and crush it to a particle size of 300-500nm;

[0019] (2) Take each raw material according to the ratio, prepare a chitosan solution with a concentration of 20% in deionized water, then add deionized water twice the volume of the chitosan solution, heat to 40°C, add butyl cyanoacrylate, poly Vinyl alcohol, hydroquinone, soybean protein powder, and aloe vera nanopowder are mixed and stirred evenly, and the solid content is adjusted to 20%.

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PUM

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Abstract

The invention discloses a new medical material. The new material is prepared from the following raw materials in parts by mass: 80-150 parts of butyl cyanoacrylate, 0.01-0.1 part of hydroquinone, 5-24 parts of aloe nano micro-powder, 20-55 parts of soybean protein powder, 10-44 parts of chitosan, 1-5 parts of acetic acid and 8-18 parts of polyvinyl alcohol. According to the new medical material disclosed by the invention, the impact resistance is enhanced by the aloe nano micro-powder, and the product degradability is improved by the natural plant extraction essence and ingredients; the bacterium inhibiting activity of the product is enhanced by the chitosan component; and the product has the advantages of moderate curing speed, high bonding strength, low heat release in bonding, good toughness of a bonding film and little skin irritation, and realizes a high-strength quick bonding effect on various wounds and operative incisions while avoiding scars after curing.

Description

technical field [0001] The invention relates to a new medical material and belongs to the technical field of medical auxiliary products. Background technique [0002] Medical glue is an emerging medical product that replaces sewing needles. The main component of medical glue is a-cyanoacrylate, which has the fastest polymerization speed in biological tissues. Under the action of anions in wound blood and interstitial fluid, medical glue can quickly polymerize and solidify to form a film and inlay tightly with the wound, which can firmly maintain the apposition state of the wound, and the glue film can prevent blood cells and platelets from passing through. Under the joint action of protein, the broken small blood vessels on the wound surface can be effectively stopped bleeding, while the adhesive film isolates the tissue and bacteria, and also has the effect of anti-infection and protection of the wound surface. The ether chain in the polymer also has analgesic effect, so m...

Claims

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Application Information

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IPC IPC(8): A61L24/00A61L24/08
CPCA61L24/0005A61L24/001A61L24/0015A61L2300/232A61L2300/404
Inventor 黄朝阳
Owner FOSHAN MINGQIAN TECH
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