Acarbose-containing pharmaceutical composition for treating diabetes and preparation method thereof
The technology of acarbose and its composition is applied in the field of pharmaceutical compositions for treating diabetes and its preparation, which can solve the problems such as restricting the use of acarbose, and achieve the effects of avoiding adverse reactions, improving therapeutic effects and having less side effects.
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Embodiment 1
[0038] A kind of pharmaceutical composition for treating diabetes, is made up of the crude drug of following proportioning by weight:
[0039] Acarbose 50g, dwarf bayberry fruit 3000g, nosebleed thunder 3000g, chaotic tree 3000g, bluegrass 3000g.
[0040]The preparation method of the pharmaceutical composition for treating diabetes:
[0041] a. Add water to decoct dwarf red bayberry fruit, nosebleed thunder, chaotic tree, and bluegrass for 2 times, add 7 volumes of water for the first time, decoct for 1.5 hours, add 5 times the volume of medicine for the second time, decoct Boil for 1 hour, combine the decoction and set aside;
[0042] b. Concentrate the decoction solution at 60°C and -0.06Mpa to a clear paste with a relative density of 1.08~1.12, add ethanol until the alcohol content is 75%, leave it for 12 hours, filter, and concentrate the filtrate to a relative density of 1.15~1.20 clear ointment, spray-dried to obtain dry powder;
[0043] c. mixing the acarbose with th...
Embodiment 2
[0047] A kind of pharmaceutical composition for treating diabetes, is made up of the crude drug of following proportioning by weight:
[0048] Acarbose 40g, dwarf bayberry fruit 3500g, nosebleed thunder 2500g, chaotic tree 3500g, bluegrass 2500g.
[0049] The preparation method of the pharmaceutical composition for treating diabetes:
[0050] a. Add water to decoct dwarf bayberry fruit, nosebleed thunder, chanting tree, and bluegrass for 2 times, add 8 volumes of water for the first time, decoct for 2 hours, add 6 times the volume of medicine for the second time, decoct Cook for 1.5 hours, combine the decoction liquid, and set aside;
[0051] b. Concentrate the decoction solution at 55°C and -0.08Mpa to a clear paste with a relative density of 1.08~1.12, add ethanol until the alcohol content is 75%, leave it for 12 hours, filter, and concentrate the filtrate to a relative density of 1.15~1.20 clear ointment, spray-dried to obtain dry powder;
[0052] c. mixing the acarbose ...
Embodiment 3
[0056] A kind of pharmaceutical composition for treating diabetes, is made up of the crude drug of following proportioning by weight:
[0057] Acarbose 60g, dwarf bayberry fruit 2500g, nosebleed thunder 3500g, chaotic tree 2500g, bluegrass 3500g.
[0058] The preparation method of the pharmaceutical composition for treating diabetes:
[0059] a. Add water to decoct dwarf red bayberry fruit, nosebleed thunder, chaotic tree, and bluegrass for 2 times, add 6 volumes of water for the first time, decoct for 1 hour, add water 4 times the volume of the medicine for the second time, decoct Boil for 0.5 hours, combine the decoction and set aside;
[0060] b. Concentrate the decoction liquid at 65°C and -0.04Mpa into a clear paste with a relative density of 1.08~1.12, add ethanol until the alcohol content is 75%, leave it for 12 hours, filter, and concentrate the filtrate to a relative density of 1.15~1.20 clear ointment, spray-dried to obtain dry powder;
[0061] c. mixing the acarb...
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