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Natural powerful bactericidal rose liquid soap and preparation method thereof

A technology of hand sanitizer and rose, which is applied in the field of daily chemical industry, can solve the problems of insufficient antibacterial and disinfection ability of hand sanitizer, skin damage, etc., and achieve the effect of superior antibacterial and disinfection ability, convenient implementation, and convenient industrial production

Active Publication Date: 2016-06-22
GANSU DONGFANG TIANRUN ROSE TECH DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most domestic hand sanitizers on the market add cationic surfactants. Although they have two functions of cleaning and disinfection, some hand sanitizers have insufficient antibacterial and disinfection capabilities.
Some hand sanitizers use synthetic substances and organic solvents, and long-term use can cause irreversible damage to the skin

Method used

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  • Natural powerful bactericidal rose liquid soap and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation of embodiment 1 natural strong antiseptic rose hand sanitizer

[0018] 1. Preparation of natural strong antiseptic rose hand sanitizer

[0019] Rose hand sanitizer prescription: 4g rose, 4g purslane, 4g skullcap, 4g berberine, 2g glycerin, 0.5g 10% fatty alcohol polyoxyethylene ether.

[0020] In the formula, rose, purslane, scutellaria baicalensis and coptis chinensis are the main functional substances, 10% m / v fatty alcohol polyoxyethylene ether is the nonionic surfactant, glycerin is the humectant, and water is the solvent.

[0021] The specific preparation steps are as follows: Weigh rose, purslane, scutellaria baicalensis, and coptis chinensis according to the prescription amount, crush them, extract with 30% v / v ethanol at 60°C under reflux for 4 hours, add absolute ethanol to ethanol in the extract The concentration is 70% v / v, the precipitate is removed by filtration, the ethanol is recovered from the filtrate, the prescription amount of glyceri...

Embodiment 2

[0028] Embodiment 2 Natural powerful antiseptic rose hand sanitizer removes DPPH free radical (diphenylpicryl free radical) test

[0029] The DPPH method was used to evaluate the free radical scavenging ability of natural strong antiseptic rose hand sanitizer, that is, the antioxidant capacity. Diphenylpicryl radical (DPPH) is a very stable nitrogen-centered radical.

[0030] 1. Add 160 μl of 0.1777 mmol / LDPPH solution to the 96-well plate.

[0031] 2. Add 80 μl / well of the sample solution to be tested, add an equal amount of absolute ethanol to the blank group, and mix well.

[0032] 3. Measure the absorbance at 520nm after 10 minutes.

[0033] 4. The measurement was repeated 3 times for each group of samples, and the average value was taken.

[0034] 5. Calculate the scavenging rate of free radicals. Clearance rate (%)=[1-(A sample / A blank]×100%

[0035] Table 1 The scavenging rate of hydroxyl free radicals by different hand sanitizer formulations

[0036] gro...

Embodiment 3

[0038] Embodiment 3 natural strong antibacterial rose hand sanitizer external antibacterial test

[0039] 1. Biomaterials

[0040] (1) Staphylococcus aureus ATCC29213 was purchased from American Type Culture Collection (ATCC).

[0041] (2) Escherichia coli Escherichia coli ATCC25922 was purchased from American Type Culture Collection (ATCC).

[0042] (3) Pseudomonas aeruginosa ATCC27853 was purchased from American Type Culture Collection (ATCC).

[0043] The antibacterial test operation was carried out on Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa by using the disc method (diameter 1cm). Take 10 μl of the test solution and drop it on a sterile paper, then place the paper in the culture medium, incubate at 37°C for 24 hours, and measure the zone of inhibition. The test results showed that the high and medium concentration samples of the rose hand sanitizer had better inhibitory effects on Staphylococcus aureus and Escherichia coli, while the 10-fold d...

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Abstract

The invention discloses natural powerful bactericidal rose liquid soap and a preparation method thereof, and belongs to the field of daily chemicals. The natural powerful bactericidal rose liquid soap is prepared from flos rosae rugosae, herba portulacae, radix scutellariae, coptis chinensis alcohol extract, nonionic surfactant, glycerinum and deionized water, and has whitening and bactericidal functions.

Description

technical field [0001] The invention relates to a natural strong antiseptic rose hand sanitizer and a preparation method thereof, belonging to the field of daily chemical industry. Background technique [0002] Hand sanitizer is a kind of skin cleanser, which is widely used in public places such as families, hotels, restaurants, airports, stations and hospitals. The hand sanitizer device with bottle body and pump head squeezes the amount to avoid cross-infection when different groups of people use it, so it is generally welcomed by consumers. The main components of hand sanitizer are amphiphilic substances with surface activity. In order to increase the antibacterial effect, cationic surfactants are often used. However, long-term use of a large amount of surfactants will cause erosion of the stratum corneum of the skin. The disposable hand sanitizer that has been promoted in recent years contains volatile amphiphilic organic solvents, and long-term use will also cause ski...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/10A61Q19/02A61Q19/00A61P31/02A61K8/9789
CPCA61K8/97A61Q17/005A61Q19/00A61Q19/02A61Q19/10
Inventor 不公告发明人
Owner GANSU DONGFANG TIANRUN ROSE TECH DEV CO LTD
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