Difunctional compound containing hindered phenol and crown ether structures, synthetic method and application thereof
A synthesis method and technology of hindered phenols, applied in the direction of organic chemistry, etc., can solve the problem of reducing the antioxidant effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0113] Under nitrogen protection, 220g of 2,6-di-tert-butyl-p-cresol and 150g of dimethyl sulfate were dissolved in 2.5L of dry chloroform. The reaction solution was heated to 60° C. under stirring in a 5 L three-necked flask, and the reaction continued for 1.5 hours. The reaction solution was cooled to 25°C and extracted four times with 1LO.5 mol / L potassium carbonate solution, and the organic layer was dried with anhydrous magnesium sulfate for 24 hours. The anhydrous magnesium sulfate desiccant in the solution was removed by filtration, and the solvent was distilled off under reduced pressure to obtain 215.3 g of 2,6-di-tert-butyl-p-methylanisole, with a yield of 92%.
[0114] Under nitrogen protection, 215.3g of 2,6-di-tert-butyl-p-methylanisole was added into a 5L three-necked flask containing 3L of carbon tetrachloride. Then add 161g of N-bromosuccinimide and 2g of azobisisobutyronitrile, heat the reaction solution to 77°C for 3 hours and stop heating, cool the reaction...
Embodiment 2
[0125] Under nitrogen protection, 220g of 2,6-di-tert-butyl-p-cresol and 150g of dimethyl sulfate were dissolved in 2.5L of dry chloroform. The reaction solution was heated to 60° C. under stirring in a 5 L three-necked flask, and the reaction continued for 1.5 hours. The reaction solution was cooled to 25°C and extracted four times with 1LO.5 mol / L potassium carbonate solution, and the organic layer was dried with anhydrous magnesium sulfate for 24 hours. The anhydrous magnesium sulfate desiccant in the solution was removed by filtration, and the solvent was evaporated under pressure to obtain 215.3 g of 2,6-di-tert-butyl-p-methylanisole, with a yield of 92%.
[0126] Under nitrogen protection, 215.3g of 2,6-di-tert-butyl-p-methylanisole was added into a 5L three-necked flask containing 3L of carbon tetrachloride. Then add 161g of N-bromosuccinimide and 2g of azobisisobutyronitrile, heat the reaction solution to 77°C for 3 hours and stop heating, cool the reaction solution t...
Embodiment 3
[0137] Under nitrogen protection, 220g of 2,6-di-tert-butyl-p-cresol and 150g of dimethyl sulfate were dissolved in 2.5L of dry chloroform. The reaction solution was heated to 60° C. under stirring in a 5 L three-necked flask, and the reaction continued for 1.5 hours. The reaction solution was cooled to 25°C and extracted four times with 1LO.5 mol / L potassium carbonate solution, and the organic layer was dried with anhydrous magnesium sulfate for 24 hours. The anhydrous magnesium sulfate desiccant in the solution was removed by filtration, and the solvent was distilled off under reduced pressure to obtain 215.3 g of 2,6-di-tert-butyl-p-methylanisole, with a yield of 92%.
[0138] Under nitrogen protection, 215.3g of 2,6-di-tert-butyl-p-methylanisole was added into a 5L three-necked flask containing 3L of carbon tetrachloride. Then add 161g of N-bromosuccinimide and 2g of azobisisobutyronitrile, heat the reaction solution to 77°C for 3 hours and stop heating, cool the reaction...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More