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Application of donkey-hide gelatin in preparing medicine for treating infertility or health-care products

A technology for infertility and health care products, which is applied in the directions of drug combination, function of food ingredients, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2016-07-20
SHAN DONG DONG E E JIAO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, whether donkey-hide gelatin has a therapeutic effect on infertility has not been reported at home and abroad.

Method used

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  • Application of donkey-hide gelatin in preparing medicine for treating infertility or health-care products
  • Application of donkey-hide gelatin in preparing medicine for treating infertility or health-care products
  • Application of donkey-hide gelatin in preparing medicine for treating infertility or health-care products

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0047] Experimental Example 1 Study on the Effect of Ejiao on Premature Ovarian Failure

[0048] 1. Experimental method

[0049] 1.1 Experimental animal feeding and modeling grouping

[0050] 1.1.1 Experimental animal feeding:

[0051] Animal quarantine: Quarantine for 5 days after receiving animals;

[0052] Breeding environment and conditions: SD rats were reared in SPF animal room of Shanghai Institute of Family Planning Science (China Fertility Regulatory Drug Toxicology Testing Center); hours, 12 hours in darkness; quarantined for 5 days before the start of the animal experiment, and adaptively raised until the age and weight of the animals reached the experimental requirements. After general behavior observation, rats that met the requirements were selected as experimental animals; they were raised in 400×350×200mm3 plastic cages , 3 rats of the same sex were raised in each cage; free access to water and food.

[0053] Feed, bedding and drinking water: Feed is breedi...

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Abstract

The invention discloses application of donkey-hide gelatin in preparing medicine for treating infertility or health-care products, and belongs to the field of new medical application of donkey-hide gelatin.According to the application, on the basis that cyclophosphamide is used for establishing a premature ovarian failure animal model, the influences of donkey-hide gelatin on the weight, weight gaining, the food ration, the estrous cycle, the ovary organ coefficient, the gonadal hormone level, the histopathology, the follicle count and the like of animals suffering from the premature ovarian failure are observed, it is found through experiment results that donkey-hide gelatin has a certain effect on body weight recovery of female mice obtained after cyclophosphamide modeling, has the tendency of increasing the ovaries, uterus weight and organ coefficients of female mice and has a certain up-regulation effect on follicle development, and it is indicated that donkey-hide gelatin has the effect of increasing the ovary coefficient and improving the ovary function.It means that donkey-hide gelatin has a treatment effect on infertility and can be applied to preparing medicine for treating infertility or health-care products.

Description

technical field [0001] The invention relates to new medical uses of donkey-hide gelatin, in particular to the use of donkey-hide gelatin in the preparation of medicines or health care products for treating infertility, and belongs to the field of new medical uses of donkey-hide gelatin. Background technique [0002] Premature ovarian failure (POF) refers to ovarian failure and amenorrhea due to depletion of ovarian follicles or iatrogenic damage in women before the age of 40, and is mainly characterized by low estrogen levels and high gonadotropins. According to statistics, the incidence of this disease is between 1% and 3%. The function of ovarian synthetic sex hormones is low or cannot be synthesized, which reduces the negative feedback effect on the pituitary gland, the ovarian reserve follicles are extremely reduced or exhausted, and the ovary develops into atrophic changes. pregnant. In amenorrhea population, its incidence rate is 4%-10%. The natural pregnancy rate o...

Claims

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Application Information

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IPC IPC(8): A61K35/36A61P15/08A23L33/00A23L2/38
CPCA23L2/38A61K35/36A23V2002/00A23V2200/30
Inventor 孙祖越周祥山周莉顾建军史兆松
Owner SHAN DONG DONG E E JIAO
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