Preparation method of acanthopanax obovatus Hoo polysaccharide iron and application thereof

A technology of Acanthopanax ovalifolia and polysaccharide iron, which is applied in the field of drug synthesis, can solve the problems of high daily cost, and achieve the effects of low production cost, operability, and reliable process conditions

Inactive Publication Date: 2016-07-20
宋逍
View PDF3 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the high daily cost of the drug, medium and small hospitals do not use it as the first choice for the treatment of iron deficiency anemia.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of acanthopanax obovatus Hoo polysaccharide iron and application thereof
  • Preparation method of acanthopanax obovatus Hoo polysaccharide iron and application thereof
  • Preparation method of acanthopanax obovatus Hoo polysaccharide iron and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A preparation method of Acanthopanax obtusa polysaccharide iron, specifically according to the following steps:

[0027] Step 1: Extract Acanthopanax Obovatus polysaccharide: Dry the rhizome of Acanthopanax obovata at 80℃, smash it through a 60-mesh sieve, weigh 8g of the pulverized Acanthopanax obtusa rhizome, and use 12 times the volume Reflux the dehydrated ethanol for degreasing twice, 1h each time, filter, dry the filter residue, use double distilled water, according to the material-to-liquid ratio 1:14g / mL, extract once at 75℃, combine the extracts, and then press 1g The medicinal materials are concentrated into 1 mL for concentration, and Sevage reagent is added to the concentrated solution so that the volume ratio of the concentrated solution to Sevage reagent is 1:4. After being thoroughly mixed by a 2500r / min homogenizer, centrifuged, the supernatant is taken and the Sevage reagent is added. The volume ratio of the supernatant to the Sevage reagent is 1:4. The Se...

Embodiment 2

[0034] A preparation method of Acanthopanax obtusa polysaccharide iron, specifically according to the following steps:

[0035] Step 1: Extract Acanthopanax Obovata polysaccharide: Dry the rhizome of Acanthopanax obovata at 80℃, smash it through a 60-mesh sieve, weigh 10g of the smashed Acanthopanax rhizome and use 10 times the volume Reflux the absolute ethanol for 2 times, 3h each time, filter, dry the filter residue, use double distilled water, according to the material-to-liquid ratio 1:15g / mL, extract 3 times at 80℃, combine the extracts, and then press 1g The medicinal materials are concentrated into 1 mL for concentration, and the Sevage reagent is added to the concentrated solution so that the volume ratio of the concentrated solution to the Sevage reagent is 1:5. The concentrated solution is thoroughly mixed with a 3000r / min homogenizer and then centrifuged. The supernatant is taken and then the Sevage reagent is added. The volume ratio of the supernatant to the Sevage r...

Embodiment 3

[0042] A preparation method of Acanthopanax obtusa polysaccharide iron, specifically according to the following steps:

[0043] Step 1: Extract Acanthopanax Obovatus Polysaccharide: Dry the rhizome of Acanthopanax Obovata at 80℃, smash it through a 60-mesh sieve, weigh 12g of the pulverized Acanthopanax obtusa rhizome, and use 8 times the volume The absolute ethanol is refluxed for 2 times, 2h each time, filtered, and the filter residue is air-dried, then use double distilled water, according to the material-to-liquid ratio of 1:16g / mL, extract 2 times at 85℃, combine the extracts, and then press 1g. The medicinal materials are concentrated into 1 mL for concentration, and Sevage reagent is added to the concentrated solution so that the volume ratio of the concentrated solution to Sevage reagent is 1:6. After being thoroughly mixed by a 3500r / min homogenizer, centrifuged, the supernatant is taken and then Sevage reagent is added. The volume ratio of the supernatant to the Sevage ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
concentrationaaaaaaaaaa
concentrationaaaaaaaaaa
Login to view more

Abstract

The invention discloses a preparation method of acanthopanax obovatus Hoo polysaccharide iron and application of the acanthopanax obovatus Hoo polysaccharide iron, and belongs to the technical field of pharmaceutical synthesis. The preparation of the acanthopanax obovatus Hoo polysaccharide iron particularly comprises the following steps: 1, preparing an acanthopanax obovatus Hoo polysaccharide composite membrane; 2, preparing the acanthopanax obovatus Hoo polysaccharide iron. The preparation method of the invention has less reaction steps, mild reaction conditions, good reproducibility and reliable process conditions, and further has operability and suitability for industrial production. In addition, an iron supplement preparation provided by the invention is good in iron supplementing effect, low in production cost and small in side effect on intestines and stomach.

Description

Technical field [0001] The invention belongs to the technical field of drug synthesis, and specifically relates to a preparation method and application of Acanthopanax obovatus iron. Background technique [0002] At present, iron deficiency anemia is one of the most common diseases in the world, which seriously affects people's physical ability and intelligence, especially the elderly, children and women are more likely to suffer from iron deficiency due to their physical characteristics. According to WHO report: The incidence of iron deficiency anemia in men is 10% in men, 20% in women, 40% in pregnant women, and as high as 52% in children; the 2010 national public nutrition survey in my country shows that the incidence of iron deficiency anemia in the world It is more than 17%, and the proportion of women’s iron deficiency is as high as 35.6%; iron deficiency can cause children’s growth retardation and mental retardation. Iron deficiency in pregnant women significantly increase...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00A61K31/715A61P7/06A61P3/02
CPCC08B37/00A61K33/26
Inventor 宋逍段玺赵鹏唐志书王昌利
Owner 宋逍
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap