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Application of bamboo shaving polysaccharides in immunoregulation and tumor resisting

An immunoregulatory and anti-tumor technology, applied in anti-tumor drugs, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of high cost and limited drug sources, achieve sufficient raw materials, optimal physiological activity, and achieve high The effect of value utilization

Active Publication Date: 2016-07-27
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the sources of these drugs are relatively limited and the cost is high

Method used

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  • Application of bamboo shaving polysaccharides in immunoregulation and tumor resisting
  • Application of bamboo shaving polysaccharides in immunoregulation and tumor resisting
  • Application of bamboo shaving polysaccharides in immunoregulation and tumor resisting

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1, the preparation method of Zhuru polysaccharide, carry out the following steps successively:

[0050] 1) Steam explosion pretreatment

[0051] Put 1kg of bamboo (Phyllostachysheterocycllavar.pubescens (Mazel) Ohwi) bamboo (bamboo shavings are crushed to 10-20 mesh after natural air-drying, moisture content about 15%) into a high-density steam blasting machine (Hebi Zhengdao Bio-Energy Co., Ltd. Manufacture, QBS-200B type) in the material chamber (5L), when the steam pressure is 2.2MPa, the maintenance pressure is 1min, and it explodes instantly (the explosion time is 0.005075s≤T≤0.008752s). Put the steam-exploded wet material into an oven at 80±1°C to dry to a moisture content of about 15%, which is convenient for storage.

[0052] 2) water extraction

[0053] Weigh 50g of the dewaxed bamboo rutabaga raw material (that is, the steam-explosively dried bamboo rutabaga obtained in step 1), add 750mL of distilled water, extract in a water bath at 95°C for 2h,...

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Abstract

The invention discloses application of bamboo shaving polysaccharides in immunoregulation and tumor resisting. The bamboo shaving polysaccharides have the polysaccharide content not lower than 94.2% and are free of protein; tumors comprise gastric cancer, lung cancer, liver cancer and the like. According to the application, the bamboo shaving polysaccharides (BSPs) are applied to the preparation of anticancer drugs and immunoregulators, and the expression of Th1 / Th2 cytokines is enhanced, so that the bamboo shaving polysaccharides are applied for cancer therapy.

Description

technical field [0001] The invention relates to the anti-tumor immunoregulatory effect of bamboo rutabaga polysaccharide, which belongs to the application of plant active ingredients in medical treatment and health care products. Background technique [0002] Cancer is one of the most important diseases that plague human health. According to the "Global Cancer Report 2014" released by the World Health Organization (WHO), the number of new cancer cases in my country ranks first. Among the four types of malignant tumors including liver, esophagus, stomach and lung, China ranks first in the world in terms of new cases and deaths. Although with the development of science and technology, a series of cancer treatment methods have emerged, surgery, radiotherapy and chemotherapy accompanying surgery are still the gold standard for cancer treatment. However, these treatment methods often lead to severe adverse reactions such as nausea, vomiting, liver function damage, low immunity, ...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61P37/04A61P35/00
CPCA61K31/715A61K36/899
Inventor 闵军霞李广宇张英张亦然王福俤
Owner ZHEJIANG UNIV
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