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External traditional Chinese medicine composition and preparation with functions of relieving allergy and resisting inflammation and preparation method thereof

The technology of a composition and a skin care composition, applied in the field of skin care preparations, can solve the problems of easy recurrence and single efficacy, and achieve the effects of easy acceptance, simple preparation method and easy acquisition.

Inactive Publication Date: 2016-10-05
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, most of the skin care products with anti-allergic effects on the market are mainly moisturizing, which can only alleviate and control allergies, and are prone to repeated attacks
And the effect is single, and it cannot solve the uneven pigmentation caused by allergies while resisting allergies

Method used

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  • External traditional Chinese medicine composition and preparation with functions of relieving allergy and resisting inflammation and preparation method thereof
  • External traditional Chinese medicine composition and preparation with functions of relieving allergy and resisting inflammation and preparation method thereof
  • External traditional Chinese medicine composition and preparation with functions of relieving allergy and resisting inflammation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The preparation of embodiment 1 Chinese medicine composition of the present invention

[0051] (1) After the following raw materials are pulverized, weigh and mix them according to the weight ratio;

[0052] Vine tea 30g, Fangfeng 20g, Sophora flavescens 20g, Angelica 20g, Ophiopogon japonicus 10g, Dogwood 10g

[0053] (2) extract with 75% ethanol by volume percentage, the mass volume ratio of crude drug to ethanol g / ml is 1:13, and extract for 3 hours at 70°C;

[0054] (3) cooling the extract obtained in step (2) to room temperature (20°C), and filtering through 100 mesh to obtain the filtrate;

[0055] (4) The filtrate is mixed with 1,3-butanediol in the original amount of ethanol, spreads a 1.2 μm filter plate in a Buchner funnel, vacuum-filters the filtrate obtained above, and collects the filtrate.

Embodiment 2

[0056] The preparation of embodiment 2 Chinese medicine composition of the present invention

[0057] (1) After the following raw materials are pulverized, weigh and mix them according to the weight ratio;

[0058] Vine tea 60g, Fangfeng 10g, Sophora flavescens 40g, Angelica 10g, Ophiopogon japonicus 20g, Dogwood 40g

[0059] (2) extract with 95% ethanol by volume, the mass volume ratio of crude drug to ethanol (g / ml) is 1:30, extract at 90°C for 1 hour;

[0060] (3) cooling the extract obtained in step (2) to room temperature (30° C.), and filtering through 200 mesh to obtain the filtrate;

[0061] (4) The filtrate is mixed with 1,3-butanediol in the original amount of ethanol, spreads a 1.2 μm filter plate in a Buchner funnel, vacuum-filters the filtrate obtained above, and collects the filtrate.

Embodiment 3

[0062] The preparation of embodiment 3 Chinese medicine composition of the present invention

[0063] (1) After the following raw materials are pulverized, weigh and mix them according to the weight ratio;

[0064] Vine tea 20g, Fangfeng 40g, Sophora flavescens 10g, Angelica 40g, Ophiopogon japonicus 40g, Cornus officinalis 20g

[0065] (2) extract with 60% ethanol by volume percentage, the mass volume ratio of crude drug and ethanol g / ml is 1:10, and extract for 4 hours at 80°C;

[0066] (3) cooling the extract obtained in step (2) to room temperature (25° C.), and filtering through 200 mesh to obtain the filtrate;

[0067] (4) Add the original amount of ethanol and 1,3-butanediol to the filtrate to mix evenly, spread a 1.2 μm filter plate in the Buchner funnel, vacuum filter the obtained filtrate, and collect the filtrate.

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Abstract

The invention discloses an external traditional Chinese medicine composition with functions of relieving allergy and resisting inflammation. The composition is prepared from, by weight, 2-6 parts of Ampelopsis megalophylla Diels et Gilg, 1-4 parts of radix sileris, 1-4 parts of radix sophorae flavescentis, 1-4 parts of radix angelicae sinensis, 1-4 parts of radix ophiopogonis and 1-4 parts of cornus officinalis. It is proved through experiments that the composition is safe and free of irritation to skin, has effective allergy restraining and itching stopping functions, and has an effect on restraining I-type hypersensitivity through inhibitor IL-6, and has an effect on restraining IV-type hypersensitivity through inhibitor IL-8. By reducing the increase of expression of protein, with induction MAPKs channel ERK, of PMACI, the effect of restraining inflammatory factor high expression can be achieved, and therefore the inflammation and allergy caused by the improvement of permeability of blood capillary and the release of histamine are restrained, and the composition has a good function for other skin injuries such as sunburn. The composition has a function of whitening skin and preserving moisture and has an effect on shielding skin.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for external use, in particular to a traditional Chinese medicine composition for external use with soothing and anti-inflammatory effects and a skin care preparation prepared from the traditional Chinese medicine composition for external use. Background technique [0002] In recent years, large-scale smog incidents have broken out in most parts of China. The impact of smog on health in Beijing is a topic of great concern to the public and has attracted widespread social attention. The impact of PM2.5 on human health includes many On the one hand, their commonality is the oxidative stress, inflammatory response, and immune system dysfunction caused by inhalation into the human body, which in turn leads to the rapid increase of sensitive people, and skin sensitivity is one of the symptoms. According to the domestic epidemiological survey, the incidence of allergic diseases in my country...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K8/97A61P37/08A61P29/00A61P17/04A61Q19/00A61Q19/02
Inventor 邓薇刘光荣李丽孟宏
Owner INFINITUS (CHINA) CO LTD