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Chinese and western compound preparation for treating traumatic epilepsy and preparation method

A technology for traumatic epilepsy and compound preparations, applied in the field of medicine, can solve problems such as memory loss, cerebellar damage, unresponsiveness, etc., and achieve the effect of improving disease resistance and making patients relaxed and happy.

Inactive Publication Date: 2016-11-09
李若龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, patients with recurrent early or mid-term traumatic epilepsy should be treated with systematic antibacterial drugs, generally according to the type of seizures, such as grand mal seizures and localized seizures, antiepileptic drugs such as phenytoin, etc., psychomotor seizures are the first choice Carbamazepine, but in the process of long-term medication, patients show side effects such as drowsiness, memory loss, unresponsiveness, depression, etc., and even cause cerebellar damage, while traditional Chinese medicine has no side effects, but the effect is slower, so it is necessary to develop a new treatment Compound preparations for traumatic epilepsy

Method used

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  • Chinese and western compound preparation for treating traumatic epilepsy and preparation method

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Effect test

Embodiment 1

[0043] The composition and parts by weight of the ingredients of the compound preparation of the present invention are as follows: 92 parts of polygala, 89 parts of Shichangpu, 87 parts of Guiyujian, 85 parts of turmeric, 82 parts of antelope horns, 77 parts of frankincense, 74 parts of Armillaria, plantain 72 parts of oil, 70 parts of mint, 67 parts of barley dendrobium, 65 parts of longan meat, 63 parts of bamboo leaves, 61 parts of Gentiana chinensis, 57 parts of fork furunculosis, 56 parts of lotus seeds, 1.9 parts of carbamazepine, 1.7 parts of topiramate, 1.6 parts of celery, 1.2 parts of midazolam.

[0044] The processing steps of compound preparation preparation method of the present invention are:

[0045] (1) Mix polygala, dendrobium and longan meat in a container, add ethanol with a volume concentration of 70% to 80% and 3 to 5 times distilled water relative to the mass of the mixture, and soak for 20 to 24 hours Afterwards, heat and reflux for 2 to 3 hours, filter...

Embodiment 2

[0054] The composition and parts by weight of the ingredients of the compound preparation of the present invention are as follows: 85 parts of polygala, 82 parts of Shichangpu, 80 parts of Guiyujian, 78 parts of turmeric, 75 parts of antelope horn, 70 parts of frankincense, 68 parts of armillaria, plantain 65 parts of oil, 64 parts of mint, 60 parts of wheat dendrobium, 58 parts of longan meat, 56 parts of bamboo leaves, 55 parts of Gentiana chinensis, 51 parts of fork furunculosis medicine, 50 parts of lotus seeds, 1.5 parts of carbamazepine, 1.4 parts of topiramate, quasi 1.3 parts of milk, 0.9 parts of midazolam.

[0055] The preparation method of the compound preparation of the present embodiment has the same process steps, usage and dosage as in Example 1.

Embodiment 3

[0057] The composition and parts by weight of the ingredients of the compound preparation of the present invention are as follows: 77 parts of Polygalaceae, 75 parts of Iris, 73 parts of Guiyujian, 71 parts of Curcuma, 68 parts of Antelope Horn, 63 parts of Frankincense, 59 parts of Armillaria, plantain 58 parts of oil, 57 parts of mint, 53 parts of wheat dendrobium, 49 parts of longan meat, 49 parts of bamboo leaves, 48 ​​parts of Gentiana chinensis, 44 parts of fork furunculosis medicine, 43 parts of lotus seeds, 1.1 parts of carbamazepine, 0.9 parts of topiramate, quasi 0.8 part of ketone, 0.6 part of midazolam.

[0058] The preparation method of the compound preparation of the present embodiment has the same process steps, usage and dosage as in Example 1.

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Abstract

The invention discloses a Chinese and western compound preparation for treating traumatic epilepsy and a preparation method, and belongs to the technical field of medicine. The compound preparation is prepared from polygala roots, rhizoma acori graminei, herb of buchnera cruciata Ham., radix curcumae, antelope horns, frankincense, amillariella mellea, Japanese banana juice, herba menthae, longan aril, bamboo leaves, radix gentianae macrophyllae, herb of passiflora cupiformis Mast., lotus seeds, carbamazepine, topiramate, quazepam and midazolam. According to the compound preparation, the traditional Chinese medicinal materials which have the effects of clearing heat and nourishing the heart, harmonizing blood and relaxing muscles and tendons, clearing away heat and promoting urination and removing mania and calming epilepsy and western medicine which has the effects of tranquilizing and allaying excitement, relieving depression and resisting convulsions are combined to act on all the organs such as the lung, the heart, the liver and the kidney, and therefore the compound preparation can make rapid response to the traumatic epilepsy and resist anxiety and convulsions, has the effects of calming and muscle relaxing, can block release of excitatory neurotransmitters to lower the nerve excitability, aims at fundamentally treating the traumatic epilepsy and gradually improving the disease resistance of a patient and achieves the effect of treating both symptoms and root causes.

Description

Technical field [0001] The invention relates to the technical field of medicine, in particular to a Chinese and Western compound preparation for treating traumatic epilepsy and a preparation method thereof. Background technique [0002] Traumatic epilepsy refers to epileptic seizures secondary to craniocerebral injury, which can occur at any time after the injury. The early ones appear immediately after the injury, and the late ones can start to have sudden seizures many years after the head injury has recovered. Not all patients with traumatic brain injury suffer from epilepsy, and the onset time and situation vary greatly. Traumatic epilepsy occurs mostly in young men. [0003] Clinical manifestations of traumatic epilepsy: [0004] 1. Seizure forms [0005] Any type of epilepsy can occur except for petit mals and severe bilateral myoclonus. Frontopolar meningoencephalic epilepsy often causes grand mal seizures without aura; lesions in the central frontoparietal area o...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/48A61P25/08A61K31/137A61K31/55A61K31/5517A61K35/32
CPCA61K9/1617A61K31/137A61K31/55A61K31/5517A61K35/32A61K36/07A61K36/185A61K36/324A61K36/51A61K36/534A61K36/62A61K36/69A61K36/77A61K36/80A61K36/88A61K36/888A61K36/898A61K36/899A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 李若龙王延林王东宝
Owner 李若龙
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