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Cannula packer containing citrate

A technology of citrate and tube sealer, which is applied to devices introduced into the body and other medical devices, can solve problems such as inconvenient operation, tissue necrosis, catheter blockage, etc., achieve good analgesic effect, reduce erythrocyte sedimentation rate, and relieve pain Sensitive effect

Inactive Publication Date: 2016-11-09
北京远方通达医药技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this device can realize this medical operation, it is inconvenient to operate, and the three-way pipeline needs to be converted, and the three-way pipeline is a disposable product, and the cost is relatively high
[0005] In the prior art, intravenous indwelling catheters usually cause or cause catheter blockage, blood return, bruising, heat pain, phlebitis, and venous thrombosis. In mild cases, local swelling, pain and other irritating symptoms may occur, and severe cases may cause tissue necrosis. , causing great pain to the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 The anti-stasis effect of citrate

[0040] Experimental animal grouping and treatment: 40 healthy and clean SD rats, half male and half male, were adaptively reared for 1 week and randomly divided into 4 groups: normal control group, model control group, positive control group and sodium citrate group. 10 per group. The model control group, the positive control group and the sodium citrate group were all established acute blood stasis rat models. The acute blood stasis rat model was established by intragastric administration of equal volumes of distilled water, aspirin (0.06g / kg), sodium citrate (0.06g / kg), gavage for 10 days.

[0041] The method for establishing the rat model of acute blood stasis is as follows: subcutaneously inject epinephrine hydrochloride (Adr, 8μg / kg) on ​​the back of the rat, and immerse the rat in ice water (0~2℃) for 5 minutes after Adr injection for 5 minutes, and then 4 hours apart. After that, Adr (8μg / kg) was injected again.

[0042] ...

Embodiment 2

[0050] Example 2 The anti-stasis effect of citrate

[0051] Methods: The clinical data used a randomized controlled study method. 60 patients with uremia who received hemodialysis treatment were randomly divided into two groups, all using Campbell dual-lumen dialysis indwelling catheter (internal jugular vein catheter length: 125 mm; femoral vein catheter length: 200mm ), after femoral vein or internal jugular vein puncture, establish temporary hemodialysis catheter by Seldinger method. There were 30 cases in the experimental group (group A) and 30 cases in the control group (group B). The average age of group A was 55 years old; the age of group B was 58 years old. The general clinical conditions of the two groups before hemodialysis were similar and comparable. All the catheters were indwelled in the femoral vein, with an average indwelling time of 31 days. The number of dialysis is 2~4 times / week. The intravenous indwelling catheter treatment operation is handled according...

Embodiment 3

[0054] Example 3 Anticoagulant effect of citrate

[0055] Methods: The clinical data used a randomized controlled study method. 60 patients who received hemodialysis were randomly divided into two groups, all using Campbell dual-lumen dialysis indwelling catheter (internal jugular vein catheter length: 125 mm; femoral vein catheter length: 200 mm). Puncture the femoral vein or internal jugular vein, and establish a temporary hemodialysis catheter by Seldinger's method. There were 30 cases in the experimental group (group A) and 30 cases in the control group (group B). The average age of group A was 55 years old; the age of group B was 58 years old. The general clinical conditions of the two groups before hemodialysis were similar and comparable. All the catheters were indwelled in the femoral vein, with an average indwelling time of 31 days. The number of dialysis is 2~4 times / week. The intravenous indwelling catheter treatment operation is handled according to aseptic techni...

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Abstract

The invention discloses a cannula packer containing citrate. The cannula packer containing citrate is used for packing a venous indwelling cannula, which can effectively solve the problems of catheter occlusion, blood return, stagnating, heat pain, phlebitis and phlebothrombosis formation caused by the venous indwelling cannula, the treatment effect is further improved, aching feeling of a patient is greatly relieved, and pain of the patient is reduced. It is found that citrate has excellent functions of removing and resisting stasis, can effectively reduce whole blood viscosity and plasma viscosity in acute blood stasis and reduce blood sedimentation and hematokrit and has good treatment effects of removing and resisting stasis. Citrate has excellent anti-inflammatory and pain relieving actions, can synergistically promote inflammatory factors in serum of diabetic nephropathy patients receiving hematodialysis treatment and improves the treatment effect.

Description

Technical field [0001] The invention relates to a tube sealer containing citrate. Background technique [0002] Venous indwelling pipeline is a kind of medical equipment widely used in clinical practice. Its operation is simple, safe and convenient. It not only solves the pain of patients with repeated puncture, protects the vein, but also reduces the nursing workload of nurses. It is suitable for elderly patients, children, Involuntary patients, such as patients who need multiple injections but difficult to get a needle, especially critically ill patients, can open intravenous channels at any time for early medication to improve the rescue success rate. In the process of using venous indwelling technology, tube blockage is a big problem faced by patients and nurses, and the cause of tube blockage is mostly caused by blood returning to the indwelling needle when the tube is sealed and coagulation caused by the residual drug in the cannula. , So now every time after intravenous i...

Claims

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Application Information

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IPC IPC(8): A61M39/20A61M5/14
CPCA61M5/14A61M39/20
Inventor 石峰方益胜
Owner 北京远方通达医药技术有限公司
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