61 results about "Phlebothrombosis" patented technology

An orally taken enteric Chinese medicine in the form of tablet, capsule, dripping pill, or soft capsule for treating unstable angina pectoris, acute myocardial infarction, cerebral haemorrhage, etc and preventing deep phlebothrombosis is prepared from leech. Its preparing process is also disclosed.

The present invention discloses an application of dihydromyricetin in preparation of medicine for preventing or curing angiocardiopathy. The animal tests show that the dihydromyricetin has the effect for resisting internal phlebothrombosis, can be used for effectively preventing angiocardiopathy due to thrombosis, for example cardiac disease and apoplexy. Said invention can be made into medicine or health-care product.

The present invention belongs to the field of medicine preparing technology, and is especially one kind of figwort total phenyl glycoside compound and its preparation process and application. The figwort total phenyl glycoside has main components of angole glycoside C and ergot sterioside in the weight ratio of 90-95 to 5-10 and total content over 80 wt%. It is prepared through hot alcohol extraction or alcohol percolation. Pharmaceutical experiments show that the figwort total phenyl glycoside can reduce the blood rheology of rat obviously, inhibit platelet aggregation of rat and inferior phlebothrombosis of rat, so that it may be used in preparing medicine for thromboangitis obliterans. It and pharmaceutically acceptable carrier may be form medicine composition capable of being prepared into various preparation forms, such as tablet, capsule, granule, etc.

A Chinese medicine in the form of treating vasculitis, phlebitis, phlebothrombosis, lymphangitis, Raynaud's disease, etc is prepared from 6 Chinese-medicinal materials including pangolin scales, red sage root, dahurian angelica root, Chinese angelica root, etc through decocting four of them twice, concentrating the decoction, mixing with the powder of others, drying, pulverizing, sieving and loading in capsules.

The invention discloses a nursing device for vascular surgery. The nursing device comprises a bed frame, and a baffle is fixedly arranged at the left end of the upper surface of the bed frame; a bed board is fixedly installed on the upper surface of the bed frame, and telescopic supporting legs are arranged on the lower surface of the bed frame; the left sides of the front and rear side faces of the bed frame are both provided with an anti-falling mechanism, the right sides of the front and rear side faces of the bed frame are both provided with a leg placing part, and sliding grooves are formed in the right sides of the front and rear side faces of the bed frame respectively. The height of the bed frame can be adjusted so that the device can better adapt to different patients for use, andthe legs of each patient can be lifted. Besides, medical staff conveniently adjust the horizontal positions and heights of the leg placing parts according to lower limb conditions of the patients, lower limb varicosities and lower limb phlebothrombosis can be effectively prevented, the accident that the patients fall off a bed when turning over can be avoided, and the nursing device especially has a good protection function on elderly patients also suffering from other diseases such as diabetes.

The invention relates to a decoction for promoting blood circulation, which is prepared from the following raw materials in parts by weight: 15 to 25 parts of honeysuckle stem, 25 to 35 parts of glabrous greenbrier rhizome, 10 to 20 parts of Chinese angelica, 15 to 25 parts of root of rehmannia, 15 to 25 parts of red paeony root, 4 to 8 parts of peach seed, 6 to 12 parts of safflower, 6 to 12 parts of Chinese thorowax root, 6 to 12 parts of szechuan lovage rhizome, 8 to 16 parts of medicinal cyathula root, 15 to 25 parts of Chinese waxgourd peel, 6 to 14 parts of plantain seed, 4 to 8 parts of ricepaperplant pith, and 15 to 25 parts of suberect spatholobus stem. The decoction has the advantages that the Chinese medicament has the obvious functions of promoting blood circulation by removing blood stasis, expelling wind and removing damness, and relaxing tendons and strengthening bones. The decoction has a simple preparation process, is convenient to use, has a short course of treatment, a significant curative effect and a low price, and has good curative effect of treating limb pains, swelling, superficial venous engorgement and touchable cord-shaped objects along with veins caused by phlebothrombosis; and by taking the decoction, patients with mild symptoms can be cured in 20 days, and most patients with severe symptoms can be cured through two courses of treatment. The Chinese medicament is taken orally, and has no toxic or side effects.

The invention belongs to the technical field of medicine, and specifically relates to an injection for preventing venous thrombosis after orthopedic or surgical operations and a preparation method thereof; the active ingredients are mainly enoxaparin sodium, Tween-20, methionine, a pH regulator and Composition of water for injection. The preparation of the present invention is filled with neutral borosilicate glass ampoules, which can effectively avoid the risk of lowering the potency of the preparation and increasing the content of free sulfate radicals during the high-temperature melting and sealing process of the ampoule; at the same time, the preparation of the present invention is filled with neutral borosilicate glass ampoules. packaging, can greatly save the cost of packaging materials and improve the production capacity of the product; the preparation of the present invention has stable quality and simple process. security.

The invention relates to the technical field of medical equipment, in particular to a novel glove preventing tube drawing. The glove comprises a left glove body (1), a right glove body (2) and a girdle (3) used for fixing the belly. Two ends of the girdle (3) are connected to the left glove body (1) and the right glove body (2) through connecting strips (4). The girdle (3) is provided with an adjusting buckle (5). The wrists of glove bodies are provided with binding ropes (6). The novel glove preventing tube drawing has the following beneficial effects: a hand constraining effect is achieved; the non-planned tube drawing condition is prevented; phlebothrombosis and skin injuries caused by continuous constraints are avoided; the effect of constraining two hands is exerted well while the body and hands of a person can lean to each other; a patient feels more comfortable to lie so that two hands are located at functional positions; at the same time, blood circulation of hands is promoted and two hands are prevented against stiffness due to other kinds of gloves; hemodynamic disorders of peripheral blood are avoided.

The invention discloses application of sea cucumber enzymatic hydrolysate in preparation of a medicine for improving phlebothrombosis. The sea cucumber enzymatic hydrolysate has better in-vivo thrombolysis effect; the sea cucumber enzymatic hydrolysate has the advantages that on the one hand, thrombus can be directly improved by activating a fibrinolytic system, on the other hand, by anti-inflammatory effect, the vascular endothelial cell can be prevented from being injured, and the fibrinolytic system is indirectly protected, and certain improving effect on the phlebothrombosis is finally realized. In addition, the sea cucumber enzymatic hydrolysate can also be used for thrombolysis in vitro.

The invention provides a synthetic method of rivaroxaban metabolite 5, which belongs to the field of medicine synthesis. The provided preparation method is reasonable in process design, high in operability, moderate in reaction condition, high in yield, and capable of realizing mass production. The p-bromonitrobenzene is adopted as a raw material to synthesize the rivaroxaban metabolite 5 by virtue of eight-step reaction. The rivaroxaban metabolite 5 prepared by the invention provides important evidence for performing the quality, safety and efficacy scientific evaluation, pharmacological research, pharmacokinetics and the like of the rivaroxaban; and moreover, the rivaroxaban metabolite 5 is better in pharmacological activity, can be used for developing a drug for treating adult phlebothrombosis caused by various reasons and is high in application value.

The invention eblogns to the technical field of biology and specifically relates to a human phlebothrombosis risk gene F5 and PAI-1 polymorphism detection kit as well as a preparation method and application thereof. The kit is prepared from a detection reagent, a positive control product and a negative control product, wherein the detection reagent is used for amplifying gene F5 and PAI-1 polymorphism related to the human phlebothrombosis risk, wherein the detection reagent applied to the F5 gene polymorphism is prepared from a primer sequence, a PNA sequence and PCR reaction liquid; the primer sequence is used for amplifying an rs6025 site of F5 gene; the detection reagent applied to the PAI-1 gene polymorphism is prepared from a primer sequence, a PNA sequence and PCR reaction liquid; the primer sequence is used for amplifying an rs17999762 site of the PAI-1 gene. The kit disclosed by the invention is used for detecting the human aspirin resistance gene polymorphism and has the advantages of high flexibility, high specificity, convenience in operation, reliable results and the like; furthermore, detection can be finished within 1 hour, and result reading is simple and objective.

The invention discloses a formula for treating phlebothrombosis and a preparation method thereof. The formula for treating the phlebothrombosis in the invention comprises the following raw materials in part by weight: 20 to 40 parts of white paeony root; 20 to 40 parts of common anemarrhena rhizome; 20 to 40 parts of divaricate saposhnikovia root; 10 to 20 parts of astraolylis lancea formalyrata; 10 to 20 parts of cassia twig; 10 to 20 parts of radix stephaniae tetrandrae; 10 to 20 parts of blast-fried aconite; 10 to 20 parts of amur corktree bark; 5 to 15 parts of ephedra herb; 5 to 15 parts of liquoric root; 5 to 15 parts of fresh ginger; 10 to 20 parts of atraotydin; 50 to 70 parts of coix seed; 50 to 70 parts of honeysuckle flower; 10 to 20 parts of peach seed; 5 to 15 parts of safflower; 5 to 15 parts of sappan wood; 5 to 15 parts of diverse wormwood herb; 10 to 20 parts of myrrh; and 5 to 15 parts of frankincense. The preparation method for the formula for treating the phlebothrombosis comprises the step that when the total mass of the raw materials is 395 grams, the volume of a medicament liquid prepared by decocting the raw materials is between 1,400 and 1,500 ml. The formula for treating the phlebothrombosis has effects of warming yang and eliminating dampness, removing heat and expelling wind, and eliminating slough and promoting granulation.

The invention discloses a Chinese herbal preparation for dissolving thrombus, the Chinese herbal preparation is prepared by taking gastrodia elata and polygonum multiflorum as guiding drugs, taking hawthorn, leech, earthworm, safflower carthamus, the root of red-rooted salvia, pseudo-ginseng, isatis root, honeysuckle and dandelion as raw materials, pulverizing, grinding into fine powder, and mixing with honey to prepare honeyed boluses, wherein a weight ratio of the respective raw materials is as follows: 5 parts of hawthorn, 3 parts of leech, 8 parts of earthworm, 5 parts of safflower carthamus, 5 parts of the root of red-rooted salvia, 3 parts of pseudo-ginseng, 6 parts of isatis root, 6 parts of honeysuckle, 9 parts of dandelion and 15 parts of honey. The Chinese herbal preparation has the beneficial effects of low production cost, good thrombus prevention and treatment effect, high healing rate, fast effecting speed, and suitability for preventing and treating phlebothrombosis, artery thrombosis and microcirculation thrombus diseases as well as the treatment of inflammation thrombus diseases.

The invention belongs to the field of deep vein thrombosis prediction in biomedicine, and particularly relates to an establishment method of a deep vein thrombosis prediction model based on metabonomics. The method comprises the following steps: acquiring serum metabolite data sets of a deep vein thrombosis patient and a healthy human body; according to the conditions that VIP is greater than 1 in an orthogonal partial least square discrimination model and a P value is less than 0.05 in an independent sample t test, taking a compound meeting the conditions in the serum small molecule metabolite data set as a characteristic biomarker for deep vein thrombosis; importing the characteristic biomarker data into IBM SPSS software, and establishing a multi-layer sensor model; or importing the characteristic biomarker data into R software, and establishing a random forest model by using a Rattle package. The prediction model established by the method provided by the invention is high in detection sensitivity and good in specificity, and meets the detection requirements of early diagnosis of deep vein thrombosis.

The invention provides a pure traditional Chinese medicine preparation for treating varicosity. The pure traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials: taraxacum mongolicum, cattail pollen, sophora japonica, centella asiatica, lycium barbarum, cortex dictamni, siberian walking fern, oroxylum indicum, wild chrysanthemum flower, mulberry twigs, excoecaria acerifclia, angelica citriodora, rhizoma nerdostachyos, rhizoma arisaematis, lithospermum, air potato, gentiana macrophylla, radix achyranthis, bulbophyllum inconspicuum, spina date seeds, fleshfingered citron flower, rubia cordifolia, melandrium album, thalictrum foliolosum, cactus, abrus cantoniensis hance and pyrolusite pyrolusitum. The invention aims to provide the pure traditional Chinese medicine preparation for treating varicosity, normal working, learning and living of patients are not affected in the treatment process, and the pure traditional Chinese medicine preparation has the advantages of no pain, no damage, high recovery property, high treatment effect and no reoccurrence after treatment, metabolism of partial cell tissue can be improved, phlebothrombosis and venous blood wall deposition residues can be rapidly dissolved and removed, yin and yang can be balanced to activate blood vessel wall and remedy wall membrane, convex superficial veins can be remedied, original skin color can be recovered, and the pure traditional Chinese medicine has a miraculous treatment effect on varicosity and complication.

The invention provides traditional Chinese medicine paste for preventing and treating PICC phlebitis and phlebothrombosis. The traditional Chinese medicine paste is characterized by being prepared from, by weight, 9 g of moutan bark, 12 g of red peony roots, 15 g of the rhizome of chuanxiong, 3 g of herba asari, 6 g of rhizoma zingiberis, 28 g of the root of red-rooted salvia, 12 g of safflowers, 6 g of liquorice roots, 6 g of goldthread roots, 26 g of honeysuckle flowers, 12 g of radix angelica sinensis, 12 g of spreading hedyotis herb and 13 g of barbed skullcap herb; the component medicine is taken according to the weight ratio and ground into superfine powder, the superfine powder is mixed to be uniform, the superfine powder is added to rapeseed oil according to the proportion of 1:(4-5), and the traditional Chinese medicine paste is prepared. The ratio is simple and easy to obtain, and cost is low. The traditional Chinese medicine paste is externally applied, and use is convenient. The treatment effect is good, and no toxic or side effect exists.

The invention relates to a traditional Chinese medicine composition for treating varicosis, which is prepared from an external component and a component to be taken orally. The external component andthe component to be taken orally are simultaneously applied to improve the blood circulation of phlebothrombosis focuses from inside to outside, and have the effects of warming Yang, promoting granulation and removing toxicity, and the Chinese medicine composition can relieve the blood microcirculation disorder of focuses, increase the permeability of blood capillaries, recover the function of venous valves of lower limbs and inhibit phlebothrombosis, thus thoroughly curing varicosis. A preparation method of the traditional Chinese medicine composition for treating varicosis disclosed by the invention establishes a specific process according to the requirements of external use and oral taking, obtaining the external agent and the agent to be taken orally with good efficacy and achieving good effects of removing blood stasis, promoting blood circulation, dredging collaterals, warming Yang and relieving pain.

The invention provides an auxiliary ankle pump exerciser for preventing lower limb phlebothrombosis and a using method, and belongs to the field of medical instruments. The exerciser comprises a leg fixing assembly, a foot supporting assembly, a stretching and bending assembly and a foot fixing assembly, the leg fixing assembly and the foot supporting assembly are fixedly connected and are perpendicular to each other, the leg fixing assembly is arranged at one end of the foot fixing assembly, the foot supporting assembly is arranged on one side of the foot fixing assembly, and the foot supporting assembly drives the foot fixing assembly to swing up and down relative to the leg fixing assembly through the stretching and bending assembly. The position can be adjusted at will according to different ankle stretching and bending limit degrees, the applicability for a patient is good, ankle stretching and bending actions can be automatically completed, unattended operation is achieved, and time and energy of medical staff are greatly saved.

The invention belongs to the medicine technical field, in particular to an external medicine for curing a limb venous thrombus and phlebitis. The invention is characterized in that bean powder, pawpaw powder, myrrh powder, china root powder and radix arnebiae form loose powder according to the weight proportion of 80 to 85 percent, 7 to 8 percent, 2.5 to 4.5 percent, 3 to 5.5 percent and 2.5 to 3.5 percent respectively are taken to form loose powder and prepared into the invention via the following method: dry bean, dry pawpaw, dry myrrh, dry china root and dry radix arnebiae are taken to be broken into powder to make bean powder, pawpaw powder, myrrh powder, china root powder and radix arnebiae powder over 80 meshed sieve. The loose powder is made by mixing the components equably according to the above weight proportion after 10 to 20 minutes of sterilization treatment. The loose powder is filled in the inner seal of a medical plastic bag by 348g to 352g. When in use, the loose powder of 348g to 352g and 500 millilitre magnesium sulphate solution with the chroma of 5 to 20 percent are mixed into paste. The invention has the advantages of simple production art, scientific and reasonable prescription, accurate and obvious curative effect, short period of treatment, no pain and side effect to human body, low price and convenient treatment as a Chinese patent medicine, and is worthy to be promoted.