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Composition with effects of clearing away lung heat, reducing phlegm and stopping cough and preparation method thereof

A technology for clearing the lungs, resolving phlegm and relieving coughs and medicines, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve the problems of increasing process time and cost, increasing pollution, and long standing time, etc. Achieve significant economic and social benefits, give full play to curative effects, and take reasonable doses

Inactive Publication Date: 2016-11-16
R & D CENT OF TIANJIN ZHONGXIN PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method extracts the active ingredients of Scutellaria baicalensis incompletely, and the extract contains more impurities, which affects the therapeutic effect of the medicine.
This method also needs to use a large amount of hydrochloric acid, which is a precursor chemical, which is inconvenient to use and easily pollutes the environment
Long standing time increases process time and cost, and also increases the possibility of contamination

Method used

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  • Composition with effects of clearing away lung heat, reducing phlegm and stopping cough and preparation method thereof
  • Composition with effects of clearing away lung heat, reducing phlegm and stopping cough and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1: preparation medicine extract

[0049] 1. Prescription

[0050] 960g of Scutellaria baicalensis, 480g of trichosanthemi, 240g of Fritillaria aurantium, 240g of Citrus aurantii (stir-fried with bran removed), 240g of Bellflower, 240g of Morus alba (honey-roasted), 120g of cooked rhubarb, 120g of Anemarrhena, 120g of Ophiopogon japonicus, 120g of orange red, bitter Almonds (peeled and fried) 120g, Peucedanum 120g, Baibu 120g, licorice 30g

[0051] Second, the method

[0052] a. Take each raw material according to the ratio of raw materials, and set aside;

[0053] b. Trichosanthes extract with water twice, each time adding 6 times the amount of water, extracting for 1.5 hours, combining the extracts, concentrating under reduced pressure to obtain concentrated solution B, the density of the concentrated solution is 1.08;

[0054] c. Add ethanol to extract the rest of the herbs twice, first add 6 times of 80% ethanol to extract for 2 hours, add 4 times of 80...

Embodiment 2

[0057] Embodiment 2: preparation medicine extract

[0058] 1. Prescription

[0059] 960g of Scutellaria baicalensis, 480g of trichosanthemi, 240g of Fritillaria aurantium, 240g of Citrus aurantii (stir-fried with bran removed), 240g of Bellflower, 240g of Morus alba (honey-roasted), 120g of cooked rhubarb, 120g of Anemarrhena, 120g of Ophiopogon japonicus, 120g of orange red, bitter Almonds (peeled and fried) 120g, Peucedanum 120g, Baibu 120g, licorice 30g

[0060] Second, the method

[0061] a. Take each raw material according to the ratio of raw materials, and set aside;

[0062]b. Trichosanthes extract with water twice, add 8 times of water each time, extract for 1 hour, combine the extracts, concentrate under reduced pressure to obtain concentrated solution B, and the density of the concentrated solution is 1.15;

[0063] c. Add ethanol to the rest of the herbs and extract twice, add 6 times the amount of 50% ethanol to extract for 2 hours each time, combine the extract...

Embodiment 3

[0066] Embodiment 3: preparation tablet

[0067] Get 525g of the drug extract obtained in Example 1, add lactose 40g, microcrystalline cellulose 40g, cross-linked polyvinylpyrrolidone 40g, micronized silica gel 5g, mix uniformly, make granules, compress into tablets, and obtain tablets, each weighing 0.35g .

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PUM

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Abstract

The invention discloses a composition with effects of clearing away lung heat, reducing phlegm and stopping cough, and belongs to the field of modern traditional Chinese medicines. The composition is prepared from, by weight, 15-100 parts of radix scutellariae, 15-100 parts of radix trichosanthis, 15-50 parts of fritillary bulb, 15-50 parts of fructus aurantii, 15-50 parts of cortex mori radicis, 15-50 parts of radix platycodi, 15-50 parts of cooked rhubarb, 15-50 parts of rhizoma anemarrhenae, 15-50 parts of radix ophiopogonis, 15-50 parts of exocarpium citrus grandis, 15-50 parts of semen armeniacae amarum, 15-50 parts of radix peucedani, 15-50 parts of radix stemonae and 3-5 parts of licorice root. The composition has the advantages that according to the technical scheme, the medicine which is controllable in quality, can sufficiently exert therapeutic effects and is reasonable in taking dosage can be prepared; chemicals capable of being easily prepared into toxin are prevented from being used in the process, the process is simplified, and the composition is environmentally friendly and has remarkable economic and social benefits; the composition has remarkable economic and social benefits.

Description

technical field [0001] The invention relates to a preparation method of a medicine for clearing lung, resolving phlegm and relieving cough, belonging to the field of modern traditional Chinese medicine. Background technique [0002] Qingjin Zhisou Huatan Pill Indications: clearing the lung, reducing phlegm, and relieving cough. It is used for cough with yellow phlegm caused by lung-heat phlegm, poor chest and diaphragm, sore throat and hoarseness, and dry stool. [0003] Prescription: Scutellaria baicalensis 96g, Trichosanthes 48g, Fritillaria 24g, Citrus aurantium (stir-fried with bran removed) 24g, Campanulaceae 24g, Morus alba (honey-roasted) 24g, cooked rhubarb 12g, Anemarrhena 12g, Ophiopogon japonicus 12g, Huajuhong 12g , Bitter almond (peeled and fried) 12g, Peucedanum 12g, Baibu 12g, licorice 3g. [0004] Preparation method: Grind the above fourteen flavors into fine powder, sieve, mix well, pill with water, and dry to obtain. [0005] The prescription and prepara...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/20A61K9/16A61P11/14A61P11/10A61P11/00
CPCA61K9/1623A61K9/2054A61K36/23A61K36/346A61K36/428A61K36/484A61K36/539A61K36/605A61K36/708A61K36/736A61K36/752A61K36/8964A61K36/8966A61K36/8968A61K36/904A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 闫晓楠潘勤耿彤
Owner R & D CENT OF TIANJIN ZHONGXIN PHARM
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