Gel for treating colpitis and preparation method thereof

A technology of gel and vaginitis, which is applied in the field of gel for the treatment of vaginitis and its preparation, can solve the problems of antibiotic resistance and carcinogenicity of estrogen preparations, and achieve effective ingredients that are not destroyed, easy to operate, Obvious effect

Inactive Publication Date: 2016-12-07
NANJING ZHENGKUAN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no special treatment method. Generally, antibiotics are used to inhibit bacterial growth, or disinfectants and estrogen preparations are used. However, long-term

Method used

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  • Gel for treating colpitis and preparation method thereof
  • Gel for treating colpitis and preparation method thereof
  • Gel for treating colpitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Take 20 parts of golden hairpin, 18 parts of red Panax notoginseng, 15 parts of Xiaoyu Xiancao, 28 parts of Yunnan bitter vegetable, 14 parts of ash tree leaves, 20 parts of sorbifolium sorbifolium, add 10 times the weight of medicinal materials in water, soak for 0.5h, and fry Boil for 1 hour, filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine two decoction liquids, concentrate to 60 °C and the relative density is 1.05, add ethanol to make the alcohol content The volume percentage reaches 75%, stir, stand still, filter, and the relative density of the filtrate is 1.25 when the filtrate is concentrated to 65°C, and ethanol is recovered to obtain a concentrated solution, which is refined with silica gel, and the selected silica gel is pre-loaded into the resin column. After the concentrated solution is diluted with purified water, it passes through a reverse-phase silica gel column to ...

Embodiment 2

[0037] Take 20 parts of golden hairpin, 18 parts of red Panax notoginseng, 15 parts of Xiaoyu Xiancao, 28 parts of Yunnan bitter vegetable, 14 parts of ash tree leaves, 20 parts of sorbifolium sorbifolium, add 10 times the weight of medicinal materials in water, soak for 0.5h, and fry Boil for 1 hour, filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine two decoction liquids, concentrate to 60 °C and the relative density is 1.05, add ethanol to make the alcohol content The volume percentage reaches 75%, stir, stand still, filter, and the relative density of the filtrate is 1.25 when the filtrate is concentrated to 65°C, and ethanol is recovered to obtain a concentrated solution, which is refined with silica gel, and the selected silica gel is pre-loaded into the resin column. After the concentrated solution is diluted with purified water, it passes through a reverse-phase silica gel column to ...

Embodiment 3

[0040] Take 20 parts of golden hairpin, 18 parts of red Panax notoginseng, 15 parts of Xiaoyu Xiancao, 28 parts of Yunnan bitter vegetable, 14 parts of ash tree leaves, 20 parts of sorbifolium sorbifolium, add 10 times the weight of medicinal materials in water, soak for 0.5h, and fry Boil for 1 hour, filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine two decoction liquids, concentrate to 60 °C and the relative density is 1.05, add ethanol to make the alcohol content The volume percentage reaches 75%, stir, stand still, filter, and the relative density of the filtrate is 1.25 when the filtrate is concentrated to 65°C, and ethanol is recovered to obtain a concentrated solution, which is refined with silica gel, and the selected silica gel is pre-loaded into the resin column. After the concentrated solution is diluted with purified water, pass through a reverse-phase silica gel column to remov...

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Abstract

The invention provides a gel for treating colpitis and a preparation method thereof. The method comprises the following steps: taking 20 parts of lysionotus paucifloru maxuim, 18 parts of polygonum viviparum, 15 parts of mosla dianthera, 28 parts of picris divaricata, 14 parts of white wax leaves, 20 parts of shiny-leaved yellowhorn, 1 part of carbomer, 20 parts of propylene glycol, 2 parts of ethyl alcohol, 2 parts of azone, 3 parts of triethanolamine and 250 parts of distilled water; adding water at the weight being 10 times of the weight of the medicinal materials; soaking for 0.5h and decocting for 1 hour; filtering residues; adding water at the weight being 8 times of the weight of the medicinal materials; decocting for 1 hour; filtering the liquor. The special concentrating and drying device is adopted. The gel for treating colpitis can be applied for preparing the drug for restraining human fibrosarcoma HT-1080 cell proliferation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction, in particular to a gel for treating vaginitis and a preparation method thereof. Background technique [0002] Vaginitis is common in postmenopausal elderly women. Due to the decline of ovarian function, the level of estrogen decreases, the vaginal wall shrinks, the mucosa becomes thinner, the glycogen content in the epithelial cells decreases, the Ph value in the vagina increases, and the local resistance decreases. Bacteria are easy to invade and reproduce and cause inflammation. The main symptoms are increased vaginal discharge and genital itching and burning sensation. Examination showed that the vagina showed senile changes, epithelial atrophy, folds disappeared, and the epithelium became smooth and thin. The vaginal mucosa is congested, with small bleeding spots, and sometimes superficial ulcers. At present, there is no special treatment method. Generally, ...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/06A61P15/02A61P35/00B01D11/02F26B11/18F26B21/00F26B21/10F26B25/04
CPCA61K9/0034A61K9/06A61K36/28A61K36/53A61K36/63A61K36/704A61K36/77A61K36/898A61K47/32A61K2236/331A61K2236/39A61K2236/51A61K2236/55B01D11/0284F26B11/18F26B21/006F26B21/10F26B25/04A61K2300/00
Inventor 卞毓平
Owner NANJING ZHENGKUAN MEDICAL TECH
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