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Compound skin external preparation containing brasenia schreberi, preparation method and application thereof

A technology for external preparations and water chestnuts, applied in skin care preparations, medical preparations containing active ingredients, skin diseases, etc., can solve the problems of limited application of Chinese herbal medicines, the development of Chinese herbal medicines has not been deeply developed, etc., and achieve excellent moisturizing performance and production cost. The effect of low cost and simple preparation process

Active Publication Date: 2017-01-11
CHENGDU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the special requirements of external skin products, such as moisturizing, anti-oxidation, non-irritating, etc., and the development of Chinese herbal medicines has not been very deep, the application of Chinese herbal medicines has been limited.

Method used

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  • Compound skin external preparation containing brasenia schreberi, preparation method and application thereof
  • Compound skin external preparation containing brasenia schreberi, preparation method and application thereof
  • Compound skin external preparation containing brasenia schreberi, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] 1. Preparation of water shield powder: select 1000g of fresh water shield, wash with water, the volume is 1000ml, spray dry at 4000rpm on a homogenizer at 60°C for 30min, to obtain water shield powder, and set aside.

[0060] 2 Extraction method of stock solution:

[0061] a Add 10g of water shield powder, 10g of licorice powder, and 10g of white fungus powder to 1200ml of pure water, heat and swell at 60°C for 1 hour, and extract with homogenate for 2 hours.

[0062] b Centrifuge (6000rpm, 10min), collect the supernatant, extract the precipitate again, and combine the supernatant.

[0063] c The supernatant was passed through a polyamide column and eluted with deionized water.

[0064] d Filter the effluent, use 200-mesh gauze to filter, then filter paper, filter with a 5-micron membrane, and concentrate by ultrafiltration to 20 times the weight of the dry sample and a volume of 600ml. The prepared stock solution is a transparent viscous solution, slightly opalescent...

Embodiment 2

[0066] 1. Preparation of water shield powder: select 1000g of fresh water shield, wash with water, the volume is 1000ml, spray dry at 4000rpm on a homogenizer at 60°C for 30min, to obtain water shield powder, and set aside.

[0067] 2 Extraction method of stock solution:

[0068] a Add 15g of water shield powder, 5g of licorice powder, and 10g of white fungus powder to 1200ml of pure water, heat and swell at 60°C for 1 hour, and extract with homogenate for 2 hours.

[0069] b Centrifuge (6000rpm, 10min), collect the supernatant, extract the precipitate again, and combine the supernatant.

[0070] c The supernatant was passed through a polyamide column and eluted with deionized water.

[0071] d Filter the effluent, use 200-mesh gauze to filter, then filter paper, filter with a 5-micron membrane, and concentrate by ultrafiltration to 20 times the weight of the dry sample and a volume of 600ml. The prepared stock solution is a transparent viscous solution, slightly opalescent ...

Embodiment 3

[0073] 1. Preparation of water shield powder: select 1000g of fresh water shield, wash with water, the volume is 1000ml, spray dry at 4000rpm on a homogenizer at 60°C for 30min, to obtain water shield powder, and set aside.

[0074] 2 Extraction method of stock solution:

[0075] a Add 20g of water shield powder, 10g of licorice powder, and 10g of white fungus powder to 1600ml of pure water, heat and swell at 60°C for 1 hour, and extract with homogenate for 2 hours.

[0076] b Centrifuge (6000rpm, 10min), collect the supernatant, extract the precipitate again, and combine the supernatant.

[0077] c The supernatant was passed through a polyamide column and eluted with deionized water.

[0078] d Filter the effluent, use 200-mesh gauze to filter, then filter paper, filter with a 5-micron filter membrane, and concentrate by ultrafiltration to 20 times the weight of the dry sample and a volume of 800ml. The prepared stock solution is a transparent viscous solution, slightly opa...

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PUM

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Abstract

The invention discloses a raw material composition of a skin external preparation. The composition includes, by weight, 10-90 parts of brasenia schreberi powder, 10-50 parts of radix glycyrrhizae, and 5-90 parts of white fungus. The invention also discloses a skin external preparation stock solution, which includes, by weight, 10-90 parts of an extract liquid of the brasenia schreberi, 10-50 parts of an extract liquid of the radix glycyrrhizae, and 5-90 parts of an extract liquid of the white fungus. The invention also discloses a method of preparing the skin external preparation stock solution, which includes the steps of: adding the brasenia schreberi powder, radix glycyrrhizae powder and white fungus powder in water, maintaining the temperature for 1-2 h at 60 DEG C and performing extraction for 0.5-2 h, wherein the temperature is not less than 60 DEG C during extraction, and centrifuging the extract to obtain a supernatant and filtering the supernatant, purifying the supernatant through a polyamide column, and concentrating the supernatant. The invention also discloses application of the stock solution in preparation of the skin external preparation. The skin external preparation employs easy-to-obtained raw materials, is low in cost, has quite excellent moisturizing, anti-oxidizing and free radical removal performances, is simple in preparation method and low in production cost, and is free of organic solvent, pigment and tanning.

Description

technical field [0001] The invention belongs to the field of external skin preparations, and in particular relates to a raw material and stock solution of a compound external skin preparation containing water shield, a preparation method and application thereof. Background technique [0002] When evaluating the quality of external skin preparations (especially cosmetic preparations), in addition to moisturizing type, such as anti-oxidation and free radical scavenging performance are also important indicators for evaluation. The topical skin preparation with multiple excellent effects is an important research content of researchers. [0003] Existing external skin preparations generally contain a small amount of organic solvents (such as ethanol). Although the use of organic solvents facilitates the extraction of active ingredients (such as antioxidants and anti-free radical agents) in the preparations, it also causes high production costs and possible May cause adverse effe...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/97A61K36/62A61K8/02A61K8/06A61K9/06A61K9/107A61P17/18A61P17/16A61Q19/08A61Q19/02
Inventor 何正有屠银芳姚洁李维刘婧邹昆蒋用毕建军聂敏奎林明
Owner CHENGDU UNIV
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