Pemirolast potassium granule composition and preparation method thereof
A technology of pyramolast potassium and granules, which is applied in the field of pyramolast potassium granule composition and its preparation, which can solve the problems of no clinical data on the safety and effectiveness of dosage for children and adolescents, and achieve clinical safety Effective and fast-acting effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
specific Embodiment example 1
[0015] Specific implementation case 1: best
[0016] The preparation prescription of pyramolast potassium granules (in 1000 bags):
[0017]
[0018] Preparation process: Pass pyramethoxast potassium and sodium citrate through a 80-mesh sieve, pass sucrose and microcrystalline cellulose through a 65-mesh sieve, add to a wet granulator and mix evenly, use 95% ethanol as a binder, Add appropriate amount of wet granules, discharge when the particle size is about 20-40 mesh, and then dry in a hot air circulation oven at 60°C to 80°C, control the moisture content to less than 5.0%, collect the material, and pass the dry granules through a 30-mesh sieve again grain. Use an automatic granule packaging machine to pack the granules with a composite film, 1g per bag.
specific Embodiment example 2
[0019] Specific implementation case 2: tablet
[0020] The preparation prescription of pyramolast potassium granules (in 1000 tablets):
[0021]
[0022] Preparation process: pass pyrazolast potassium through a 80-mesh sieve, pass mannitol and lactose through a 65-mesh sieve, add to a wet granulator and mix evenly, use 95% ethanol as a binder, add an appropriate amount of wet granules, Discharge at about 20-40 mesh, and then dry in a hot air circulation oven at 60°C to 80°C. When the water content is controlled to be lower than 5.0%, the material is collected and granulated, and low-substituted hydroxypropyl cellulose, magnesium stearate and silicon dioxide are added to mix evenly, and the Φ6.5mm shallow concave punched tablet is controlled at a hardness of 3kg to 5kg. Aluminum-plastic packaging is the finished product.
[0023] From the foregoing examples, the following conclusions can be drawn: 20 bags of 1g pyrazolast potassium granules were dissolved with 50ml warm wa...
PUM
| Property | Measurement | Unit |
|---|---|---|
| hardness | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
Login to View More