Plant acne-removing compound as well as preparation method and applications thereof

A compound, acne-removing technology, applied in the directions of drug combinations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of large side effects of sulfur and benzoyl peroxide, drug resistance and allergy, etc., and achieve the inhibition of acne propionic acid. Bacillus, low irritant, accelerates shedding of epidermal keratinocytes

Inactive Publication Date: 2017-04-26
SOUTH CHINA INST OF COLLABORATIVE INNOVATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, sulfur and benzoyl peroxide have serious side effects and are no longer used
The second stage is from the 1970s to the end of the 20th century. In this stage, the anti-acne technology mainly relies on medical achievements, using antibiotics or antibacterial substances, such as chloramphenicol, metronidazole and dexamethasone to resist allergies. These drugs are anti-inflammatory and bactericidal. Inhibiting the growth of acne has a definite effect, but because long-term use will cause people to develop drug resistance and allergies, the cosmetic law prohibits this type of substance

Method used

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  • Plant acne-removing compound as well as preparation method and applications thereof
  • Plant acne-removing compound as well as preparation method and applications thereof
  • Plant acne-removing compound as well as preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1: the preparation of plant anti-acne compound

[0040] (1) Preparation of shallot extract: take 1 mass part of shallot, add 10 mass parts of 95% (w / w) ethanol to soak for 3 hours, then heat to 50°C for 3 hours, filter and recover the extract with 200-mesh filter cloth , ethanol is recovered by distillation under reduced pressure to obtain a thick paste containing the shallot extract, adding 1 mass part of glycerin to disperse the thick paste, adding 3 mass parts of propylene glycol to dissolve, passing through 200 mesh gauze to obtain the shallot extract.

[0041] (2) Preparation of wild chrysanthemum extract: Take 1 part by mass of wild chrysanthemum, add 10 parts by mass of 20% (w / w) propylene glycol aqueous solution, heat in a water bath at 80° C. for 3 hours, and filter through a 200-mesh filter cloth to obtain wild chrysanthemum extract.

[0042] (3) Preparation of lotus leaf extract: Take 1 part by mass of lotus leaf, add 30 parts by mass of 20% (w / w) ...

Embodiment 2

[0044] Embodiment 2: the preparation of plant anti-acne compound

[0045] (1) Preparation of shallot extract: take 3 parts by mass of shallot, add 15 parts by mass of 95% (w / w) ethanol, soak for 5 hours, then heat to 60°C and soak for 4 hours, filter and extract with 200-mesh filter cloth liquid, and the ethanol was recovered by distillation under reduced pressure to obtain a thick paste containing the shallot extract, adding 3 parts by mass of glycerin to disperse the thick paste, adding 10 parts by mass of propylene glycol to dissolve, and passing through 200 mesh gauze to obtain the shallot extract.

[0046] (2) Preparation of wild chrysanthemum extract: take 1 mass part of wild chrysanthemum, add 30 mass parts of 20% (w / w) propylene glycol aqueous solution, heat in a water bath at 80° C. for 4 hours, and filter through a 200-mesh filter cloth to obtain wild chrysanthemum extract.

[0047] (3) Preparation of lotus leaf extract: take 1 part by mass of lotus leaf, add 10 part...

Embodiment 3

[0049] Embodiment 3: the preparation of plant anti-acne compound

[0050] (1) Preparation of shallot extract: Take 5 parts by mass of shallot, add 20 parts by mass of 95% (w / w) ethanol, soak for 6 hours, then heat to 70°C and soak for 5 hours, filter and extract with 200-mesh filter cloth Liquid, the ethanol is recovered by distillation under reduced pressure to obtain a thick paste containing the shallot extract, add 3 parts by mass of glycerin to disperse the thick paste, add 15 parts by mass of propylene glycol to dissolve, pass through 200 mesh gauze, and obtain the shallot extract.

[0051] (2) Preparation of wild chrysanthemum extract: take 1 mass part of wild chrysanthemum, add 20 mass parts of 20% (w / w) propylene glycol aqueous solution, heat in a water bath at 80° C. for 5 hours, and filter through a 200-mesh filter cloth to obtain wild chrysanthemum extract.

[0052] (3) Preparation of lotus leaf extract: take 1 part by mass of lotus leaf, add 30 parts by mass of 20%...

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Abstract

The invention belongs to the technical field of cosmetics, and discloses a plant acne-removing compound as well as a preparation method and applications of the plant acne-removing compound. The plant acne-removing compound is prepared from the following components in parts by weight: 40-80 parts of shallot extracting solution, 10-20 parts of wild chrysanthemum flower extracting solution, 10-20 parts of lotus leaf extracting solution, and 2-10 parts of betaine salicylate. The shallot extracting solution can effectively inhibit the breeding of propionibacterium acnes and kill bacteria; the lotus leaf extracting solution can effectively control the secretion of skin sebum; the wild chrysanthemum flower extracting solution has the effects of clearing away heat and toxic materials, and diminishing inflammation; betaine salicylate can accelerate the falling of the human epidermal keratinocytes; through the synergistic effect of the four components, the plant acne-removing compound achieves the effect of inhibiting propionibacterium acnes from the formation mechanism of acnes.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a plant acne-removing compound and its preparation method and application. Background technique [0002] Acne, known as "acne" in traditional Chinese medicine, commonly known as acne, is a chronic inflammatory skin disease that occurs in the pilosebaceous glands. Acne mainly occurs in the head and face, neck, chest, back and other parts rich in sebaceous glands. According to reports, the incidence of acne in different degrees in adolescence is as high as 85%. Acne is prone to scars, which seriously affects the appearance of patients and further affects their psychological produce adverse effects. Therefore, acne-removing cosmetics with the claims of preventing and treating acne are very popular with acne patients and have a broad market prospect. [0003] The technical development of acne-removing cosmetics has roughly gone through three stages: the first stage wa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K8/44A61Q19/00A61Q17/00A61P17/10
CPCA61K8/97A61K8/44A61Q17/005A61Q19/00
Inventor 程建华郑华生张鹏谢培镇谢明容陈杰烽黄桂州何衍健
Owner SOUTH CHINA INST OF COLLABORATIVE INNOVATION
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