Micro-fluidic chip based on MHD control

Abstract

The invention discloses a micro-fluidic chip based on MHD control. The micro-fluidic chip is invented based on Ac MHD driving technology; a three layer structure is adopted; the first layer is a PDMS cover plate layer 16, is provided with electrode connection columns 12, an injection port 19, and an observing port 20 hole; the second layer is micro-channel layer 17 comprising an Ac MHD driving pump 11, a micro channel 15, a liquid storage chamber 21, and a detection chamber 22, wherein the Ac MHD driving pump 11 comprises the electrode connection columns 12, electrodes 13, and a micro solenoid coil 14 right below a micro channel 15; the third layer is quartz glass slice 18 provided with a groove via caving, and the groove is used for accommodating the micro solenoid coil 14. In applications, samples or reagents are injected into different liquid storage chambers 21, and flow into a preset detection chamber 22 for analysis under the control of Ac MHD driving pump, multipath simultaneous detection can be realized, detection efficiency is increased, and the micro-fluidic chip possesses practical application value.

Description

technical field [0001] The invention relates to a microfluidic control chip based on MHD control, which belongs to the field of mechanical technology. Background technique [0002] Microfluidic chip technology integrates the basic operation units of sample preparation, reaction, separation, and detection in the process of biological, chemical, and medical analysis into a micron-scale chip to complete the entire analysis process. The analysis and detection of samples on a micron-level chip only requires microliter or even nanoliter samples and reagents, and its cost is greatly reduced compared with high-throughput analysis systems. conditions of. Most of the microfluidic chips currently on the market can only analyze and detect a single sample, using a mechanical drive method, which has low sensitivity and is too large to be conducive to the development of integration. [0003] Chinese patent application number: 201510191236.2, titled "Nucleic acid automatic extraction micr...

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Problems solved by technology

This type of low sensitivity, complex structure, and excessive volume are not conducive to the development of integration

Chinese patent application number: 200980120537.9, the device named "analysis device and analysis method using capillary electrophoresis" and Chinese patent application number: 201410355409.5, the chip named "a new type of large-channel electrophoresis microchip" is being implemented The voltages used in the process reach 600V and 1000V respectively. Such high voltages not only affect the activity of the samples to be tested, but also may cause electrochemical reactions, and even pose a threat to the safety of operators.

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