Application of tocotrienol derivative

A technology of use and medicine, applied in the field of use of tocotrienol derivatives, can solve the problems of increasing the risk of secondary bone marrow disease in the later stage
CN106668031AInactive Publication Date: 2017-05-17BEIJING WEILANZHIYUAN MEDICAL TECH CO LTD
3 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING WEILANZHIYUAN MEDICAL TECH CO LTD
Publication Date
2017-05-17
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to application of a compound as shown in the general formula (I) or pharmaceutically acceptable salt in the preparation of medicines for preventing and / or treating cytopenia of patents who will receive, is receiving or has received chemotherapy and drug therapy. In the general formula, R1, R2 and R3 can be the same or different and respectively and independently represent H or C1-C3 alkyl group. In comparison with common clinical drugs (such as G-CSF) for increasing haemocyte count for those who receive chemotherapy, the compound of the invention can remarkably increase hemocyte in those who receive chemotherapy, especially increase leucocyte, in particular the number of neutrophile granulocyte and monocyte. The compound of the invention has a good clinical prospect.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a compound of general formula (I) as described and defined herein or a pharmaceutically acceptable salt thereof for the preparation of a medicament for the prevention and / or treatment of cytopenias in subjects who will, are or have been treated with chemotherapeutic drugs use in . Background technique

[0002] For the treatment of neoplastic diseases, a large number of chemotherapeutic drugs have been recommended. However, chemotherapeutic drugs are often nonspecific and toxic to normal cells. Chemotherapy drugs often produce various side effects in patients receiving chemotherapy.

[0003] Myelosuppression is one of the main side effects of chemotherapy drugs. Clinically, the bone marrow hematopoietic system of patients receiving chemotherapy is extremely vulnerable to damage, specifically manifested as decreased peripheral blood leukocyte count, neutrophil count decrease and / or thrombocytopenia. At present, some c...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More