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Periplaneta americana composition for treating chronic prostatitis and preparation method of periplaneta americana composition

A technology for chronic prostatitis and American cockroach, applied in the field of medicine, can solve the problems of compound sulfamethoxazole tablets with large side effects, high drug resistance, low cure rate, low effective rate, etc. , the effect of less adverse reactions

Inactive Publication Date: 2017-05-31
KUNMING SINOWAY NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The present invention provides a Periplaneta americana composition for treating chronic prostatitis and a preparation method thereof, which solves the problems of low cure rate and effective rate in treating chronic prostatitis with existing compound sulfamethoxazole tablets and Periplaneta americana extracts, and Compound sulfamethoxazole tablets have serious side effects and high drug resistance

Method used

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preparation example Construction

[0036] The preparation of Periplaneta americana extract, according to the method of patent CN 102885857B, comprises the following steps:

[0037] A, pulverizing: the dry Periplaneta americana body is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0038] B, immersion: soak the American cockroach coarse powder gained in step a with the ethanol of concentration 90~95%, make the ethanol liquid level higher than the coarse powder liquid level 5~10cm airtight preservation and make the coarse powder mixed solution;

[0039] c. Extraction: Carry out reflux extraction of the coarse powder mixed solution obtained in step b at a temperature of 70 to 85°C for 4 times, and when the coarse powder mixed solution is extracted for the first time, add 5 times the weight of the coarse powder with 92% ethanol , the extraction time was 5 hours; after the second time, the ethanol with a concentration of 92% of 5 times the weight of coarse powder was extracted each time, and...

Embodiment 1

[0044] A preparation method of a Periplaneta americana composition for treating chronic prostatitis, comprising the following steps:

[0045] (1) The preparation of the Periplaneta americana extract, the method and steps are as described above, and it is set aside.

[0046] (2) Mixing of active ingredients: weigh according to the weight ratio of Periplaneta americana extract: trimethoprim: sulfamethoxazole=32g:80g:320g, mix uniformly, make active ingredient mixture, for subsequent use;

[0047] (3) Proprietary medicine: get above-mentioned active ingredient mixture and starch 80g, dextrin 40g, microcrystalline cellulose 200g, carboxymethyl starch sodium 30g mix uniformly, granulate, then add magnesium stearate 1g, mix well, press into 2000 Tablets, that is, oral tablets. Each tablet contains 16mg of Periplaneta americana extract, 40mg of trimethoprim, and 160mg of sulfamethoxazole.

Embodiment 2

[0049] A preparation method of a Periplaneta americana composition for treating chronic prostatitis, comprising the following steps:

[0050] (1) The preparation of the Periplaneta americana extract, the method and steps are as described above, and it is set aside.

[0051] (2) Mixing of active ingredients: weigh according to the weight ratio of Periplaneta americana extract: trimethoprim: sulfamethoxazole=80g:80g:320g, mix uniformly, make active ingredient mixture, for subsequent use;

[0052] (3) Proprietary medicine: get above-mentioned active ingredient mixture and microcrystalline cellulose 150g, lactose 100g, sodium carboxymethyl cellulose 20g mix uniformly, granulate, then add magnesium stearate 0.8g, mix well, fill hard capsule into 3000 granules, that is, oral hard capsules. Each capsule contains 27mg of Periplaneta americana extract, 27mg of trimethoprim, and 107mg of sulfamethoxazole.

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Abstract

The invention relates to a periplaneta americana composition for treating chronic prostatitis and a preparation method of the periplaneta americana composition. The periplaneta americana composition mainly consists of a mixture of effective components of a periplaneta americana extract, trimethoprim and sulfamethoxazole in a weight ratio of (1-4):2.5:10. The treatment effect (the effective rate is 80% or greater) of the periplaneta americana composition provided by the invention in treating chronic prostatitis is remarkably prior to that (the effective rate is about 60%) of a control medicine, namely, a compound sulfamethoxazole tablet, and the cure rate can be greatly increased. In addition, comprehensive adverse reaction data shows that by adopting the composition, toxic and side effects of the compound sulfamethoxazole tablet which is used independently can be reduced to a certain extent.

Description

technical field [0001] The invention relates to a Periplaneta americana composition for treating chronic prostatitis and a preparation method thereof, belonging to the field of medicine. Background technique [0002] Prostatitis is a common disease in men, and the patients are mainly young and middle-aged. Prostatitis is an acute and chronic inflammation, mainly caused by local or systemic symptoms caused by prostate-specific and non-specific infections, which can easily lead to male infertility symptoms and sexual dysfunction. In 1995, NIH divided prostatitis into 4 types, type I: acute bacterial prostatitis, type II: chronic bacterial prostatitis, type III: chronic nonbacterial prostatitis / chronic pelvic pain syndrome, type IV: asymptomatic Sexual prostatitis. Among them, non-bacterial prostatitis is far more common than bacterial prostatitis. Prostatitis has symptoms such as frequent urination, urgency, dysuria, urethral discomfort or burning during urination, and type...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P13/08A61P31/00A61K31/505A61K31/635
CPCA61K31/505A61K31/635A61K35/63A61K2300/00
Inventor 郝振平徐溧
Owner KUNMING SINOWAY NATURAL PHARMA
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