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Traditional Chinese medicine preparation taking tripterygium glycoside as guiding drug, preparation method and application of traditional Chinese medicine preparation

A traditional Chinese medicine preparation, the technology of tripterygium wilfordii, which is applied in the field of medicinal wine and its preparation, can solve the problems of low adverse reaction rate, large toxic side effects and weak toxicity of rheumatoid arthritis, and achieve remarkable curative effect and easy Manipulation, toxicity reduction effects

Inactive Publication Date: 2017-05-31
郭静波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The first object of the present invention is to provide a traditional Chinese medicine preparation of Tripterygium wilfordii as medicine primer, to solve the problem of large toxic and side effects of tripterygium wilfordii in the treatment of rheumatoid arthritis. It has the advantages of high effective rate, low adverse reaction rate, weak toxicity, etc.

Method used

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  • Traditional Chinese medicine preparation taking tripterygium glycoside as guiding drug, preparation method and application of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation taking tripterygium glycoside as guiding drug, preparation method and application of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation taking tripterygium glycoside as guiding drug, preparation method and application of traditional Chinese medicine preparation

Examples

Experimental program
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Effect test

Embodiment 1

[0063] The traditional Chinese medicine preparation of Tripterygium wilfordii used as medicine primer provided in this embodiment includes the medicine priming liquid prepared by 300g Tripterygium wilfordii and 100g orange peel, and the following Chinese medicine components: Anemarrhena 70g, gypsum 20g, cassia twig 90g, licorice 50g, Qingfengteng 90g, Forsythia 10g, Phellodendron 10g, Pittosporum 90g, Turmeric 50g, Clematis 70g, Dihuang 190g, Fangji 50g, Danpi 20g, Radix Paeoniae Rubra 20g, Coix Seed 70g, Gardenia 70g, Talc 20g, Scrophulariae 70g , Ophiopogon japonicus 50g, Gentiana 50g, Centipede 10g, Black snake 3g, Earthworm 10g, Pinellia 40g and Campanulaceae 30g.

[0064] Its preparation method comprises the following steps:

[0065] (1), add tripterygium wilfordii and tangerine peel into 3000ml of water and soak for 2 hours, first heat to boiling with strong fire, then change to slow fire and decoct for 2 hours to obtain 800ml of medicine priming solution;

[0066] (2),...

Embodiment 2

[0068] The traditional Chinese medicine preparation of Tripterygium wilfordii used as medicine primer provided in this example includes the medicine priming solution prepared by 400g Tripterygium wilfordii and 200g orange peel, and the following Chinese medicine components: Anemarrhena 90g, Gypsum 40g, Guizhi 110g, Glycyrrhizae 70g, Caulis chinensis 110g, Forsythia 30g, Phellodendron 30g, Pittosporum 110g, Turmeric 70g, Clematis 90g, Rehmannia glutinosa 210g, Fangji 70g, Danpi 40g, Radix Paeoniae Rubra 40g, Coix seed 90g, Gardenia 90g, Talc 40g, Scrophularia 90g , Ophiopogon japonicus 70g, Gentiana 70g, Centipede 20g, Snake 6g, Earthworm 30g, Pinellia 60g and Campanulaceae 40g.

[0069] Its preparation method comprises the following steps:

[0070] (1), add tripterygium wilfordii and tangerine peel into 4000ml of water and soak for 2 hours, first heat it to boiling with strong fire, then change to slow fire and decoct for 2 hours to obtain 1200ml medicine priming solution;

...

Embodiment 3

[0073] The traditional Chinese medicine preparation of Tripterygium wilfordii as medicine primer provided in this example includes the medicine priming liquid prepared by 320g Tripterygium wilfordii and 150g orange peel, and the following Chinese medicine components: Anemarrhena 75g, Gypsum 25g, Guizhi 95g, Glycyrrhizae 55g, Caulis Sinensis 95g, Forsythia 15g, Phellodendron 15g, Pittosporum 95g, Turmeric 55g, Clematis 75g, Dihuang 195g, Fangji 55g, Danpi 25g, Radix Paeoniae Rubra 25g, Coix Seed 75g, Gardenia 75g, Talc 25g, Scrophulariae 75g , Ophiopogon japonicus 55g, Gentiana 55g, Centipede 10g, Black snake 3g, Earthworm 15g, Pinellia 45g and Campanulaceae 32g.

[0074] Its preparation method comprises the following steps:

[0075] (1), add tripterygium wilfordii and tangerine peel to 3500ml of water and soak for 3 hours, first heat it to boiling with strong fire, then change to slow fire and decoct for 3 hours to obtain 1000ml medicine priming solution;

[0076] (2), add th...

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Abstract

The invention provides a traditional Chinese medicine preparation taking tripterygium glycoside as a guiding drug, a preparation method and application of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from guiding drug liquid, rhizoma anemarrhenae, gypsum, cassia twig, liquorice, caulis sinomenii, fructus forsythia, golden cypress, bark of himalayan coralbean, turmeric, radix clematidis, rehmannia, tetrandra root, cortex moutan, red peony root, semen coicis, jasmine, talc, radix scrophulariae, radix ophiopogonis, large-leaved gentian, centipede, zaocys dhumnade, lumbricus, processed pinellia tuber and platycodon grandiflorum, wherein the guiding drug liquid is prepared from 300-400 parts of tripterygium glycoside and 100-200 parts of dried tangerine or orange peels. The traditional Chinese medicine preparation taking the tripterygium glycoside as the guiding drug has the advantages of high efficiency, low adverse reaction rate, low toxicity, and the like. The traditional Chinese medicine preparation taking the tripterygium glycoside as the guiding drug is used for preparing the medicine for treating rheumatoid arthritis, especially the rheumatoid arthritis with the traditional Chinese medicine syndrome of acute rheumatic fever.

Description

technical field [0001] The invention relates to the technical field of preparation of traditional Chinese medicines, in particular to a medicinal wine using tripterygium wilfordii as medicine and its preparation method and application. Background technique [0002] Rheumatoid arthritis is a chronic, multisystemic, inflammatory autoimmune disease mainly involving peripheral joints. Its clinical manifestations are mainly symmetrical, persistent joint swelling and pain, often accompanied by morning stiffness. The pathological manifestations are chronic inflammation of the synovial membrane, pannus formation, and destruction of joints and cartilage. It affects 1% of the world's population, causing severe functional impairment, permanent disability, and an increasing mortality rate. At present, the commonly used drugs for the treatment of rheumatoid arthritis in the world include non-steroidal anti-inflammatory drugs, disease-modifying anti-rheumatic drugs, biological agents, a...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P19/02A61P29/00A61K35/648A61K35/62A61K35/583A61K33/12A61K33/06
CPCA61K9/0095A61K33/06A61K33/12A61K35/583A61K35/62A61K35/648A61K36/346A61K36/37A61K36/48A61K36/484A61K36/51A61K36/54A61K36/59A61K36/634A61K36/65A61K36/71A61K36/716A61K36/744A61K36/752A61K36/756A61K36/804A61K36/808A61K36/8888A61K36/8964A61K36/8968A61K36/8994A61K36/9066A61K2236/331A61K2236/333A61K2300/00
Inventor 郭静波杨立宇朱宏日
Owner 郭静波
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