Pharmaceutical composition comprising extracts of symplococs chinesis and astragalus membranaceus for preventing and treating arthritis, and method for preparing same

Abstract

The invention relates to a pharmaceutical composition comprising extracts of Symplococs chinesis and Astragalus membranaceus for preventing and treating arthritis, and a method for preparing the same. More particularly, the invention provides a pharmaceutical composition comprising, as active ingredients, extracts of Symplococs chinesis and Astragalus membranaceus for preventing or treating arthritis, and a method for preparing the composition comprising the steps of: preparing medicinal herbs including Symplococs chinesis and Astragalus membranaceus; and adding water or C1-4 alcohol to the prepared medicinal herbs to extract the same.

Description

technical field [0001] The present invention relates to a pharmaceutical composition for the prevention or treatment of arthritis comprising a mountain alum extract and an astragalus extract and a preparation method thereof. Background technique [0002] Arthritis, as a representative of cartilage-related diseases, is roughly divided into rheumatoid arthritis (rheumatoid arthritis) and degenerative arthritis (degenerative arthritis, osteoarthritis). It is also often found that the cartilage of the knee joint is damaged due to traffic accidents or excessive exercise. Injury situation. Currently, there are about 1,000,000 arthritis patients in South Korea, and the number of women is more than twice that of men, among them, especially a common disease in menopausal women (B elmonte-S.MA et al; Arthritis Rheum, 30, pp 1214-1225, 1987). [0003] Degenerative osteoarthritis (osteoarthritis) is a disease in which articular cartilage is worn away to cause local degenerative change...

AI Technical Summary

Problems solved by technology

[0006] However, pharmacotherapeutic agents only have the effect of non-specifically relieving pain or inflammatory response itself, and chondroprotective agents act only to protect joints by supplying nutrients to chondrocytes or relieving shock

Also, when steroid preparations are taken for a long time, there may be side effects such as osteoporosis, high blood pressure, diabetes, etc. due to the loss of calcium

Therefore, in most cases, drug therapy is only used for the purpose of pain relief, and permanent artificial joint replacement is the main method, but so far, there is no drug or surgery with fundamental therapeutic effect Law

[0007] Thus, in the past few decades, many studies and efforts have been made to treat degenerative arthritis, but no pathological cause or fundamental treatment has been developed yet.

For this reason, a therapeutic agent for arthritis by Chinese herbal medicine therapeutic agent and nutritional supplement has been developed recently, but its therapeutic effect and mechanism of action have not yet been elucidated (Gaby, AR et al; Antern Med Rev, 4, pp 392-402, 1999)

Therefore, these arthritic diseases only use the existing anti-inflammatory analgesics as a simple symptomatic therapy, which is not only difficult to effectively regulate the disease, but also causes side effects caused by long-term use of the drug. man caused many difficulties

Images