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Moxifloxacin hydrochloride injection for treating respiratory infection

A technology of moxifloxacin hydrochloride and injection, which is applied in the field of drug production to achieve the effect of treating respiratory tract infection

Inactive Publication Date: 2017-09-22
JIANGSU SUNAN PHARMA IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Respiratory tract infection is often combined with antibacterial and expectorant drugs in clinical treatment because of symptoms such as inflammation and phlegm. Although certain advantages of combined medication can be brought into play, it is impossible to fully utilize the advantages of the two drugs, that is, in what ratio the two drugs work synergistically. In order to obtain the ratio of the synergistic effect of the two

Method used

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  • Moxifloxacin hydrochloride injection for treating respiratory infection

Examples

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Embodiment 1

[0023] The main components and contents are 10 parts of moxifloxacin hydrochloride, 1 part of mannitol, 3 parts of ambroxol hydrochloride, 1 part of tartaric acid and 100 parts of water.

Embodiment 2

[0025] The main components and contents are 12 parts of moxifloxacin hydrochloride, 12 parts of mannitol, 5 parts of ambroxol hydrochloride, 2 parts of tartaric acid and 100 parts of water.

Embodiment 3

[0027] The main components and contents are 10 parts of moxifloxacin hydrochloride, 12 parts of mannitol, 5 parts of ambroxol hydrochloride, 1 part of tartaric acid and 100 parts of water.

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Abstract

The invention discloses a moxifloxacin hydrochloride injection for treating respiratory infection. The dosage form is an injection, and the injection comprises the following main components: 10-12 parts of moxifloxacin hydrochloride, 1-12 parts of mannitol, 3-5 parts of ambroxol hydrochloride, 1-2 parts of tartaric acid and 100 parts of water. As a further improvement scheme, a formula of the injection further contains the following components: 5-6 parts of glucose, 1-2 parts of xylitol and 1-2 parts of a lactated Ringer's solution. After adoption of the moxifloxacin hydrochloride injection provided by the invention, the respiratory infection can be effectively treated.

Description

technical field [0001] The invention belongs to the technical field of medicine production, in particular to a moxifloxacin hydrochloride injection for treating respiratory tract infection. Background technique [0002] Moxifloxacin hydrochloride (Moxifloxacin, CAS No.: 151096-09-2) is a fourth-generation fluoroquinolone chemically synthesized antibacterial drug. Moxifloxacin hydrochloride inhibits bacterial DNA helicase A subunit and topoisomerase IV. Activity, blocking the replication of DNA, thereby exerting a bactericidal effect. It has strong antibacterial activity against Gram-negative bacteria and Gram-positive bacteria, effective against mycoplasma, chlamydia, and Legionella, effective against anaerobic infection, and especially effective against some clinically common drug-resistant bacteria. It has the advantages of high drug concentration in the body, long plasma elimination half-life, good curative effect, almost no photosensitivity reaction, and no cross-resist...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/4709A61K47/26A61P11/00A61P31/04A61K31/137
CPCA61K9/0019A61K9/08A61K31/137A61K31/4709A61K47/26A61K2300/00
Inventor 俞洋卢定强陈军陆歩实徐明
Owner JIANGSU SUNAN PHARMA IND CO LTD