Biomimetic artificial bone and synthesis method thereof

A synthesis method, bionic bone technology, applied in tissue regeneration, medical science, prosthesis, etc., to achieve good biocompatibility

Active Publication Date: 2017-10-03
文阳洋 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0021] At present, neither the allograft bone nor the current synthetic artificial bone can fully meet the above requirements.

Method used

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  • Biomimetic artificial bone and synthesis method thereof
  • Biomimetic artificial bone and synthesis method thereof

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Experimental program
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Embodiment Construction

[0053] The artificial bionic bone in this embodiment is made of a polymer with excellent mechanical properties, chemical resistance, high temperature resistance, radiation resistance, hydrolysis resistance, creep resistance, abrasion resistance, and high cleanliness. Materials or high-strength fibers, non-degradable or partially degradable inorganic materials and degradable inorganic materials such as bioceramics with osteoconductivity and osteoinductive functions, and degradable inorganic materials are made by blending and hot pressing.

[0054] Among them: polymer materials or high-strength fibers with excellent mechanical properties, chemical resistance, high temperature resistance, radiation resistance, hydrolysis resistance, creep resistance, abrasion resistance and high cleanliness are non-degradable materials. In the product, it plays the role of constructing a honeycomb-like bone scaffold; the bioceramics with osteoconductivity and osteoinductive function can make osteobla...

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Abstract

The invention provides a biomimetic artificial bone and a synthesis method. The biomimetic artificial bone consists of 20-80% of a high polymer material by mass, 5-60% of a non-degradable or partially degradable inorganic matter by mass and 5-40% of a degradable organic matter. The method comprises such steps as implementing shaping, implementing sintering and the like. The biomimetic artificial bone provided by the invention is excellent in biocompatibility. The biomimetic artificial bone, which is consistent with or similar to a part where the biomimetic artificial bone is implanted in elasticity modulus, can avoid stress shielding when implanted for a long time. The biomimetic artificial bone is sufficient in rigidity. Inner and outer layers of the biomimetic artificial bone can be honeycombed tissue structures which are provided with enough gaps, so that growth-in of related tissue cells, blood vessels, lymphatic ducts and nerves is promoted and reconstruction of blood circulation is achieved. The biomimetic artificial bone, which contains a bone growth promoting factor, is conducive to rapid healing of an implant and primitive bone.

Description

Technical field [0001] The present invention relates to artificial bionic bone and its synthesis method. Background technique [0002] Bone is an organ with a certain shape and function. It is composed of bone cells, collagen fibers and bone matrix. It is hard and elastic. It is rich in blood vessels, lymphatic vessels and nerves. It has the functions of metabolism and growth and development, and has damage, The ability of reconstruction and wound healing, repair and regeneration. Bone matrix contains calcium salts and phosphates, which are storage warehouses for human calcium and phosphorus, and participate in the metabolism and balance of calcium and phosphorus. The bone marrow has the function of hematopoietic. [0003] Bone is mainly composed of bone, bone marrow and periosteum. There are abundant blood vessels and nerve tissues inside. Bone includes cancellous bone and compact bone. The two ends of long bones are honeycomb-shaped cancellous bone. The middle part is dense an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/44A61L27/58A61L27/56A61L27/50
CPCA61L27/446A61L27/50A61L27/56A61L27/58A61L2300/102A61L2300/412A61L2300/604A61L2430/02
Inventor 文阳洋文春景
Owner 文阳洋
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