Chewable plant soft capsule and preparation method thereof

Abstract

The invention discloses a chewable plant soft capsule. The plant soft capsule comprises a filler (i) and a shuck (ii); the filler comprises a first gelatinizer, a first elasticizer and water, wherein the first gelatinizer is chosen from one or several of carrageenan, gellan gum and modified starch; and the filler is encapsulated in the shuck, and the shuck comprises a second gelatinizer, a second elasticizer and water. The sources of the chewable plant soft capsule are plant sources, and the chewable plant soft capsule has good heat stability and is suitable for being chewed and good in mouthfeel. The invention further discloses a preparation method of the chewable plant soft capsule.

Description

technical field [0001] The invention relates to the field of soft capsules. More specifically, it relates to a chewable plant soft capsule and a preparation method thereof. Background technique [0002] As an emerging drug delivery system, soft capsules can effectively ensure good drug stability of the filling due to their unique closed soft packaging characteristics, and are widely used due to their own dose controllability and portability. With the progress and development of society, soft capsules are not only used in medicine, but also widely used in many health-enhancing health foods. For example, fish oil, vegetable oil, etc. are all preserved and used in the form of soft capsules, but the disadvantage is that : Take it, especially the elderly and children are difficult to swallow. In recent years, for the purpose of improving the ingestibility of pharmaceutical preparations, there has been an increasing demand for chewable soft capsules that can be easily taken with...

AI Technical Summary

Problems solved by technology

With the progress and development of society, soft capsules are not only used in medicine, but also widely used in many health-enhancing health foods. For example, fish oil, vegetable oil, etc. are all preserved and used in the form of soft capsules, but the disadvantage is that : Take it, especially the elderly and children are difficult to swallow

However, gelatin is used as the capsule material, which has relatively poor temperature resistance, high toughness, and difficult to bite off. It takes a lot of effort to chew, and after the capsule is chewed and broken, the greasy feeling of the filling is released all at once, and the taste is unacceptable.

[0004] The prior art still has many aspects that need to be improved while solving some problems: (1) thermal stability is poor: although the softness and chewiness of the rubber can be improved by increasing the plasticizer or maintaining a higher moisture content, But at the same time, it will also lead to sticking of soft capsules, which will affect the shelf life of the product; because gelatin is a reversible colloid, when the temperature exceeds 40°C, it is prone to adhesion and agglomeration, which limits the production and storage of gelatin chewable soft capsules, which is not conducive to Store and transport in airtight containers in summer; (2) poor chewability: gelatin chewable soft capsule skin is tough, difficult to bite off, the liquid or suspended grease filling leaks out after biting, bad drug smell and greasy oil (3) Gelatin comes from the bones and skins of animals such as pigs and cattle, and the safety of animal madness is the focus of everyone's attention; For a period of time, doubts arose from foods such as "old yogurt" and "jelly" added with industrial gelatin in the market, which reduced people's credibility to gelatin foods; and the majority of Muslims and vegetarians have taboos on gelatin products. This has largely reduced the consumer base for gelatin chewable softgels

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