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Tea leaf-sourced plant soft capsule shell and application and preparation method of tea leaf-sourced plant soft capsule

A soft capsule shell and soft capsule technology, which are applied in the directions of capsule delivery, cosmetic preparations, skin care preparations, etc., can solve the problems of easy leakage of gelatin capsule shells, adhesion and cross-linking reactions, and high pollution risks, so as to overcome the product Defects, not easy to deform and stick, overcome the effect of easy leakage

Inactive Publication Date: 2017-12-22
浙江宏辉胶丸有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the above-mentioned deficiencies in the prior art, to provide a plant-based soft capsule shell prepared based on tea extract and modified tea fiber, cellulose gum, carrageenan, gellan gum, etc., and a processing method thereof. The plant soft capsule shell is rich in functional active substances of tea and has excellent quality. It can be used in the fields of medicine, food and health care products, daily chemical products, etc. It solves the problems of easy leakage, slow disintegration, adhesion and cross-linking reaction of the traditional gelatin capsule shell. Issues of animal origin, high risk of contamination

Method used

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  • Tea leaf-sourced plant soft capsule shell and application and preparation method of tea leaf-sourced plant soft capsule

Examples

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Embodiment 1

[0030] refer to figure 1 , the preparation method of a kind of tea plant soft capsule of the embodiment of the present invention, comprises following main steps successively:

[0031]a) Preparation of tea extract: the picked tea leaves are washed, dried, crushed, and passed through a 40-mesh sieve to obtain tea powder. The tea powder is mixed with 0.06mol / L sodium hydroxide at 1:40 (w / v, g / ml) Mix the solution evenly, that is, add 40 ml of 0.06mol / L sodium hydroxide solution for every 1 gram of tea powder; extract in a water bath at 90-100°C for 60 minutes, shake the extract once every 5 minutes; filter and concentrate the obtained concentrate after extracting in a water bath Hydrochloric acid was adjusted to pH=5.8 to obtain tea extract.

[0032] b) Preparation of modified tea fiber: take 5g of tea dregs washed to neutrality and dried by hot air in a three-necked flask with a stirring device, add 50ml of 75% ethanol, 50ml of 20% NaOH solution, and alkalinize at 30°C. The al...

Embodiment 2

[0036] In the embodiment of the present invention, the tea dregs after tea extraction are treated with enzymatic hydrolysis, and the rest of the preparation method is basically the same as in embodiment 1, the difference is:

[0037] a) Tea dregs enzymatic hydrolysis: mix 20% NaOH (or 2% dilute sulfuric acid solution) solution with tea dregs washed to neutral and dried at 10:1, (10 mL of liquid corresponds to 1 g of solid) in a water bath at 120 ° C After boiling for 30 minutes, filter and wash with water until neutral. Add 2g of tea residue fiber washed to neutrality and 100U of cellulase into a 250ml Erlenmeyer flask with a stopper, then add 100ml of 0.2mol / L HAc-NaAc buffer solution with a pH value of 4.8, place it in a constant temperature shaker Reactor at 50°C for 24-48h. After the enzymatic hydrolysis is completed, the tea dregs are removed by filtration, and the enzymatic hydrolysis solution is incorporated into the tea extract to prepare the next glue solution.

[0...

Embodiment 3

[0040] The method of enzymatic hydrolysis of the tea residue fiber is different for the soft capsules described in the examples of the present invention, and the other preparation processes are basically the same as in Example 2. In this embodiment, the cellulase for enzymatically hydrolyzing tea dregs is adjusted to one or more of the polygalacturonase, β-glucosidase, pectinase, protease and other multi-enzyme systems acting synergistically.

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Abstract

The invention is applicable to the technical field of soft capsules, and discloses a tea leaf-sourced plant soft capsule shell. The tea leaf-sourced plant soft capsule shell is prepared mainly from 50-75wt% of a tea leaf extract, 0-10wt% of modified tea fiber, 3-15wt% of carboxymethylcellulose (CMC), 0-5wt% of hydroxypropylmethyl cellulose (HPMC), 1-10wt% of carrageenan, 0.01-5wt% of gellan gum and 10-30wt% of a plasticizer, is applicable to medicines, food, health products, daily chemical products, chemical products and other capsule products, and has no special application restriction. The invention further provides a preparation method of a tea leaf-sourced plant soft capsule. The preparation method comprises the following steps: preparing the tea leaf extract, preparing the modified tea fiber, preparing a gum solution and preparing a soft capsule to obtain the tea leaf-sourced plant soft capsule. The soft capsule shell contains a variety of active substances contained in tea leaves, and thus has pharmacological activity and a health-care efficacy; various physical and chemical indexes meet requirements of relevant standards; the soft capsule shell can also be processed by using the conventional gelatin capsule processing equipment, so that the equipment utilization rate is improved; raw materials are low in cost; and industrial production is easy to implement.

Description

【Technical field】 [0001] The invention relates to the technical field of capsules, and relates to a preparation method of plant-based soft capsules, in particular to a high-health plant-based soft capsule shell with tea as the basic raw material and its application, and a preparation method of tea-plant soft capsules. 【Background technique】 [0002] Capsule is one of the most basic dosage forms of modern medicine and functional food, and its development and application prospects are very broad. Compared with other dosage forms, soft capsules have many advantages such as beautiful appearance, precise loading, high bioavailability, strong drug stability, and can shield the bad smell of the contents at the same time. Studies have found that the quality of soft capsules is closely related to the selection and compatibility of capsule shell materials. At present, the vast majority of soft capsules are processed from gelatin as the main raw material. Reality shows that the use o...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K47/46A61K47/38A61K47/36A61K8/9789A61K8/73A61K8/11A61Q19/00A23L33/105A23L33/22A23L29/262A23L29/256A23L29/269A23P10/30
CPCA61K9/4816A23L29/256A23L29/262A23L29/272A23L33/105A23L33/22A23P10/30A23V2002/00A61K8/11A61K8/73A61K8/731A61K8/97A61K47/36A61K47/38A61K47/46A61K2800/10A61Q19/00A23V2200/30A23V2250/214
Inventor 徐宏辉张雪燕谭蓉杨秀芳张士康左小博孔俊豪石丽琴金雪琴陈长海
Owner 浙江宏辉胶丸有限公司
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