Composite chlorhexidine oral disinfectant and preparation method thereof

A technology of oral disinfection and chlorhexidine, which is applied in the field of disinfectant, can solve the hidden danger of increasing the harm of chlorhexidine gluconate to the body, the disinfection components cannot effectively kill anaerobic bacteria, and cannot effectively kill all anaerobic bacteria and other problems, to achieve the effect of solving astringent taste, better taste and excellent killing effect

Inactive Publication Date: 2018-01-16
SHINVA MEDICAL INSTR CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Regarding oral disinfectants, there are mainly these kinds of best-selling products on the market: for example, Admiralty Chlorhexidine Oral Care Antibacterial Liquid developed by Shanghai Likang Disinfection High-tech Co., Ltd., its main component: chlorhexidine gluconate, and also contains menthol, Sorbitol, xylitol; its disadvantages are: the main component of disinfection, chlorhexidine gluconate, has a high content, and because it passes through the mouth, it greatly increases the hidden danger of chlorhexidine gluconate harming the body
Due to the rich variety and number of anaerobic bacteria in the special environment of the oral cavity, a single disinfectant ingredient cannot effectively kill most of the anaerobic bacteria in the oral cavity, and the bactericidal effect is not complete
[0003] Shandong Lierkang Disinfection Technology Co., Ltd. discloses a kind of cleansing oral mucosa disinfectant, its main component is: chlorhexidine gluconate; its disadvantage is: the main component of disinfection, chlorhexidine gluconate, has a high content. The oral cavity has greatly increased the hidden danger of chlorhexidine gluconate harming the body; due to the special environment of the oral cavity, there are many types and numbers of anaerobic bacteria, and a single disinfection component cannot effectively kill most of the anaerobic bacteria in the oral cavity. Incomplete
[0004] The main ingredient of the Dr. Xiao Brand Mouth Cleanser launched by Shandong Dr. Xiao Disinfection Technology Co., Ltd. is: chlorhexidine gluconate. Increased the hidden danger of chlorhexidine gluconate to the body; due to the special environment of the oral cavity, there are many types and numbers of anaerobic bacteria, and a single disinfectant component cannot effectively kill most of the anaerobic bacteria in the oral cavity, and the bactericidal effect is not complete

Method used

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  • Composite chlorhexidine oral disinfectant and preparation method thereof
  • Composite chlorhexidine oral disinfectant and preparation method thereof
  • Composite chlorhexidine oral disinfectant and preparation method thereof

Examples

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Embodiment 1

[0035] The formula of compound chlorhexidine oral disinfectant is as follows (unless otherwise specified, the following are percentages by weight, and the following examples are all the same):

[0036] Chlorhexidine gluconate 0.05%, hydrogen peroxide 5%, honeysuckle extract 3%, tea extract 3%, apple extract 3%, surfactant 0.4%, the rest is purified water.

[0037] The steps of preparation are:

[0038] (1) Stir and dissolve chlorhexidine gluconate and hydrogen peroxide in water to make liquid A;

[0039] (2) Add honeysuckle extract, tea extract, and apple extract to water and stir to make liquid B;

[0040] (3) Mix liquid A and liquid B, add a surfactant, and stir evenly to obtain a compound chlorhexidine oral disinfectant. The parts by weight of each raw material are as disclosed above.

[0041] In Examples 2-4, the main components are shown in the table below, and the balance is water.

[0042]

[0043] The data of embodiment 2-4 are all shown in the table.

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Abstract

The invention belongs to the field of disinfectants, and particularly relates to a composite chlorhexidine oral disinfectant and a preparation method thereof. The composite chlorhexidine oral disinfectant is characterized by comprising the following components in percentage by weight: 0.5-0.10% of chlorhexidini gluconate, 0.5-1.5% of hydrogen peroxide, 1.0-2.0% of a honeysuckle extract, 1.0-1.5% of an apple extract, 0.1-0.3% of a surfactant, 1.0-1.5% of a tea extract and the balance of water. Compared with a common oral disinfectant with only one single component of chlorhexidine, the composite chlorhexidine oral disinfectant has the characteristics of being small in chlorhexidine amount and good in disinfection effect, and is efficient in sterilization effect, free of irritation and safewithout residues.

Description

technical field [0001] The invention belongs to the field of disinfectant, and in particular relates to a compound chlorhexidine oral disinfectant, and also relates to a preparation method of the above-mentioned disinfectant. Background technique [0002] As for oral disinfectants, there are mainly these kinds of best-selling products on the market: for example, Admiralty Chlorhexidine Oral Care Antibacterial Liquid developed by Shanghai Likang Disinfection High-tech Co., Ltd., its main component: chlorhexidine gluconate, and also contains menthol, Sorbitol, xylitol; Its shortcoming is: the main component chlorhexidine gluconate content of disinfection is very high, because pass through oral cavity, have increased the hidden danger of chlorhexidine gluconate harm to health greatly. Due to the rich variety and number of anaerobic bacteria in the special environment of the oral cavity, a single disinfectant component cannot effectively kill most of the anaerobic bacteria in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61P1/02A61P31/02A61K31/155A61K33/40
Inventor 张恒庞元金李泽敬王超之王久儒
Owner SHINVA MEDICAL INSTR CO LTD
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