The invention discloses fruit and vegetable enzyme powder with a weight reducing function and a preparation method thereof. The fruit and vegetable enzyme powder is prepared from bananas, watermelons, pears, pineapples, apples, melons, dragon fruit, mulberries, celery, asparagus lettuce, white turnips, wax gourds, cucumbers, Chinese cabbages, bitter gourds, cherries, hawthorns, pawpaws, apricots, litchis, longan, jujubes, garlic, pepper, Chinese chives, spinach and asparagus. According to the fruit and vegetable enzyme powder, the scientific weight-reducing principle of eating less and consuming more is adopted, and after the fruit and vegetable enzyme powder is eaten for a long time according to the crowds with different habitus, the effects of reducing weight, slimming, detoxifying and beautifying skins are achieved, and malnutrition cannot be caused.