Pharmaceutical compound preparation for reducing blood sugar and blood fat and application thereof

A compound preparation and hypoglycemic technology, applied in the field of medicine, can solve problems such as unsatisfactory treatment effect, and achieve the effect of reducing content and improving treatment effect

Inactive Publication Date: 2018-01-19
GUILIN HAOXIN TECH SERVICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to age factors, pathological factors, eating habits and other reasons, most diabetic patients do not use drugs to maintain normal or near-normal levels of blood sugar and blood lipids. Although there are some reports about drugs that lower blood sugar and blood lipids, but The treatment effect is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Formula composition: in parts by weight, 20 parts of acipimox, 20 parts of ancetrapib, 20 parts of glipizide and 25 parts of acarbose, 100 parts of starch, 100 parts of microcrystalline cellulose, carboxymethyl 70 parts of sodium starch, 2-5 parts of magnesium stearate.

[0017] Coating Solution Prescription: Povidone K 30 aqueous solution.

[0018] The preparation method of tablet: take by weighing prescription quantity acipimox, ancetrapib, sodium carboxymethyl starch, microcrystalline cellulose and mix, then mix with prescription quantity glipizide and acarbose, Povidone K 30 The aqueous solution is used as a binder to make a soft material, granulated; dried;

Embodiment 2

[0020] Formula composition: in parts by weight, 15 parts of acipimox, 10 parts of ancetrapib, 15 parts of glipizide hydrochloride and 20 parts of acarbose, 100 parts of starch, 100 parts of microcrystalline cellulose, carboxymethyl 70 parts of sodium starch glycolate, 2-5 parts of magnesium stearate.

[0021] Coating Solution Prescription: Povidone K 30 aqueous solution.

[0022] The preparation method of tablet: take by weighing prescription quantity acipimox, ancetrapib, sodium carboxymethyl starch, microcrystalline cellulose and mix, then mix with prescription quantity glipizide and acarbose, Povidone K 30 The aqueous solution is used as a binder to make a soft material, granulated; dried;

Embodiment 3

[0024] Formula composition: in parts by weight, 40 parts of acipimox, 25 parts of ancetrapib, 25 parts of glipizide hydrochloride and 30 parts of acarbose, 100 parts of starch, 100 parts of microcrystalline cellulose, carboxymethyl 70 parts of sodium starch glycolate, 2-5 parts of magnesium stearate.

[0025] Coating Solution Prescription: Povidone K 30 aqueous solution.

[0026] The preparation method of tablet: take by weighing prescription quantity acipimox, ancetrapib, sodium carboxymethyl starch, microcrystalline cellulose and mix, then mix with prescription quantity glipizide and acarbose, Povidone K 30 The aqueous solution is used as a binder to make a soft material, granulated; dried;

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PUM

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Abstract

The invention relates to a pharmaceutical compound preparation for reducing blood sugar and blood fat and application thereof. The pharmaceutical compound preparation comprises the following effectiveactive components: acipimox, anacetrapib, glipizide and acarbose. According to the pharmaceutical compound preparation provided by the invention, not only can the defect of non-ideal treating effectof medicins for reducing blood sugar and blood fat in the prior art be effectively solved, but also the combination of the medicines is not a simple superposition of respective actions of all the components, but has a synergistic effect. By adoption of the pharmaceutical compound preparation provided by the invention, not only can the treating effect for diabetes be improved, but also the effect for reducing the content of triglyceride in a human body is better.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a drug compound preparation for lowering blood sugar and blood fat and its application. Background technique [0002] Diabetes is a group of metabolic disorders characterized by elevated blood glucose levels due to relative or absolute insufficiency of insulin in the body, including sugar, fat, and protein metabolic disorders and the resulting tissue and organ dysfunction; persistent high blood sugar is a basic biochemical characteristics, but accompanied by hyperlipidemia and other metabolic disorders. Hyperlipidemia is one of the important risk factors of arteriosclerosis and coronary heart disease, and is the pathological basis of cardiovascular and cerebrovascular diseases. Most diabetic patients are accompanied by hyperlipidemia in varying degrees. If the metabolic disorder cannot be corrected in time and the blood sugar and blood lipids can be lowered to normal levels, it...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7036A61K31/64A61K31/4965A61K31/421A61P3/06A61P3/10
Inventor 钟传新王君
Owner GUILIN HAOXIN TECH SERVICE
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