Pharmaceutical composition for reducing blood sugar and blood fat and application thereof

A composition and a hypoglycemic technology, applied in the field of medicine, can solve problems such as unsatisfactory treatment effect, and achieve the effect of reducing content and improving treatment effect

Inactive Publication Date: 2018-03-09
GUILIN HAOXIN TECH SERVICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to age factors, pathological factors, eating habits and other reasons, most diabetic patients do not use drugs to maintain normal or near-normal levels of blood sugar and blood lipids. Although there are some reports about drugs that lower blood sugar and blood lipids, but The treatment effect is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Formula composition: in parts by weight, 25 parts of acipimox, 20 parts of Zhibituo, 15 parts of metformin hydrochloride, 30 parts of acarbose, 100 parts of starch, 100 parts of microcrystalline cellulose, 70 parts of sodium carboxymethyl starch part, 2-5 parts of magnesium stearate.

[0017] Coating Solution Prescription: Povidone K 30 aqueous solution.

[0018] The preparation method of the tablet: take acipimox, Zhibituo, sodium carboxymethyl starch, and microcrystalline cellulose of the prescribed amount and mix them evenly, then mix them with the prescribed amount of metformin hydrochloride and acarbose, and mix them with polyvinyl chloride Ketone K 30 The aqueous solution is used as a binder to make a soft material, granulated; dried;

Embodiment 2

[0020] Formula composition: in parts by weight, 35 parts of acipimox, 24 parts of Zhibituo, 20 parts of metformin hydrochloride and 40 parts of acarbose, 100 parts of starch, 100 parts of microcrystalline cellulose, 70 parts of sodium carboxymethyl starch part, 2-5 parts of magnesium stearate.

[0021] Coating Solution Prescription: Povidone K 30 aqueous solution.

[0022] The preparation method of the tablet: take acipimox, Zhibituo, sodium carboxymethyl starch, and microcrystalline cellulose of the prescribed amount and mix them evenly, then mix them with the prescribed amount of metformin hydrochloride and acarbose, and mix them with polyvinyl chloride Ketone K 30 The aqueous solution is used as a binder to make a soft material, granulated; dried;

Embodiment 3

[0024] Formula composition: in parts by weight, 25 parts of acipimox, 20 parts of Zhibituo, 15 parts of metformin hydrochloride, 30 parts of acarbose, 100 parts of starch, 100 parts of microcrystalline cellulose, 70 parts of sodium carboxymethyl starch part, 2-5 parts of magnesium stearate.

[0025] Coating Solution Prescription: Povidone K 30 aqueous solution.

[0026] The preparation method of the tablet: take acipimox, Zhibituo, sodium carboxymethyl starch, and microcrystalline cellulose of the prescribed amount and mix them evenly, then mix them with the prescribed amount of metformin hydrochloride and acarbose, and mix them with polyvinyl chloride Ketone K 30 The aqueous solution is used as a binder to make a soft material, granulated; dried;

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PUM

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Abstract

The invention relates to a pharmaceutical composition for lowering blood sugar and blood lipid and its application. The active ingredients of the pharmaceutical composition include: acipimox, Zhibituo, metformin and acarbose. The pharmaceutical composition provided by the present invention can not only effectively solve the defects of the unsatisfactory therapeutic effect of the hypoglycemic and blood lipid drugs in the prior art, but also, the combined effect of these several drugs is not a simple superposition of the respective effects of each component, and has synergistic enhancement. effect. The pharmaceutical composition provided by the invention can not only improve the therapeutic effect on diabetes, but also have a better effect on reducing the content of triglyceride in human body.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for lowering blood sugar and blood fat and its application. Background technique [0002] Diabetes is a group of metabolic disorders characterized by elevated blood glucose levels due to relative or absolute insufficiency of insulin in the body, including sugar, fat, and protein metabolic disorders and the resulting tissue and organ dysfunction; persistent high blood sugar is a basic biochemical characteristics, but accompanied by hyperlipidemia and other metabolic disorders. Hyperlipidemia is one of the important risk factors of arteriosclerosis and coronary heart disease, and is the pathological basis of cardiovascular and cerebrovascular diseases. Most diabetic patients are accompanied by hyperlipidemia in varying degrees. If the metabolic disorder cannot be corrected in time and the blood sugar and blood lipids can be lowered to normal levels, i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/06A61P3/10A61P9/10A61K36/062A61K31/4965A61K31/155A61K31/7036
CPCA61K36/899A61K31/155A61K31/4965A61K31/7036A61K36/062A61K2236/19A61K2300/00
Inventor 钟传新王君
Owner GUILIN HAOXIN TECH SERVICE
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