Nitrite antidote as well as preparation method and application thereof
A technology of nitrite and antidote, applied in application, antidote, pharmaceutical formulation and other directions, can solve problems such as reducing animal body tolerance, prevent and alleviate sodium nitrite poisoning, reduce basal metabolism, and the preparation method is simple Effect
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Embodiment 1
[0038] The preparation method of the present embodiment nitrite antidote comprises the following steps:
[0039] 1) Mix the sodium molybdate solution with a mass fraction of 1.5% and the copper sulfate solution with a mass fraction of 2%, and react at 60°C for 30 minutes after stirring evenly to obtain basic copper molybdate; wherein, the sodium molybdate solution and copper sulfate The mass ratio of the solution is 10:2;
[0040] 2) After fully washing the basic copper molybdate obtained in step 1), drying at 60° C., and then grinding into basic copper molybdate powder;
[0041] 3) Soak the basic copper molybdate powder obtained in step 2) in a zinc sulfate solution with a zinc concentration of 300mg / L, shake for 2 hours, then centrifuge and dehydrate at a low speed, dry at 60°C, and grind to obtain the final product; basic copper molybdate The mass ratio of powder to zinc sulfate solution is 1:1.
[0042] The nitrite antidote of this embodiment can be made into pills by fu...
Embodiment 2
[0045] The preparation method of the present embodiment nitrite antidote comprises the following steps:
[0046] 1) Mix the sodium molybdate solution with a mass fraction of 2% and the copper sulfate solution with a mass fraction of 3%, stir evenly, and react at 60° C. for 45 minutes to obtain basic copper molybdate; wherein, the sodium molybdate solution and the copper sulfate solution The mass ratio is 5:2;
[0047] 2) After fully washing the basic copper molybdate obtained in step 1), drying at 60° C., and then grinding into basic copper molybdate powder;
[0048] 3) Soak the basic copper molybdate powder obtained in step 2) in a zinc sulfate solution with a zinc concentration of 450mg / L, shake for 2 hours, then centrifuge and dehydrate at a low speed, dry at 60°C, and grind to obtain the final product; basic copper molybdate The mass ratio of powder to zinc sulfate solution is 1:20.
[0049] The nitrite antidote of this embodiment can be made into tablets by adding excip...
Embodiment 3
[0051] The preparation method of the present embodiment nitrite antidote comprises the following steps:
[0052] 1) Mix the sodium molybdate solution with a mass fraction of 9% and the copper sulfate solution with a mass fraction of 12%, stir evenly, and react at 60° C. for 35 minutes to obtain basic copper molybdate; wherein, the sodium molybdate solution and the copper sulfate solution The mass ratio is 2:2;
[0053] 2) After fully washing the basic copper molybdate obtained in step 1), drying at 60° C., and then grinding into basic copper molybdate powder;
[0054] 3) Soak the basic copper molybdate powder obtained in step 2) in a zinc sulfate solution with a zinc concentration of 960mg / L, vibrate for 2.5 hours, then centrifuge and dehydrate at a low speed, dry at 60°C, and grind to obtain the product; basic molybdate The mass ratio of copper powder to zinc sulfate solution is 1:15.
[0055] The nitrite antidote of this embodiment can be further added with excipient pecti...
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