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A compound granule capable of lowering blood sugar and its preparation method

A hypoglycemic and compound technology, applied in the field of compound granules and their preparation, can solve the problems of few applied research, single application form, uncontrollable quality, etc.

Active Publication Date: 2020-05-26
炉霍雪域俄色有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the application of esse is more common in health care products, such as tea, but there is very little research on its application in medicine, and the application form is single, and the quality is uncontrollable, which seriously limits the development and application of esse

Method used

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  • A compound granule capable of lowering blood sugar and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] This embodiment provides a traditional Chinese medicine extract and a preparation method thereof. In the method, esse, astragalus, anemarrhena, Radix Ophiopogon japonicus, red peony root, wolfberry, salvia miltiorrhiza, and Chinese yam are used as raw materials and concentrated for three times. Concrete preparation method comprises the following steps:

[0031] According to the quality record, weigh 20 parts of Russian color, 6-8 parts of Astragalus, 1-3 parts of Anemarrhena, 4-6 parts of Ophiopogon japonicus, 1-3 parts of Radix Paeoniae Rubra, 2-4 parts of Lycium barbarum, 3-5 parts of Salvia miltiorrhiza, For 8-10 parts of yam, add deionized water according to the ratio of 1:10, heat and boil for extraction for 1 hour, filter to obtain the first filtrate and first filter residue; add deionized water for the first filter residue according to the ratio of 1:9, heat and boil for extraction for 1 hour , filter to obtain the second filtrate and the second filter residue; a...

Embodiment 2

[0033] This example provides a compound granule and its preparation method. The granule is prepared by using the traditional Chinese medicine extract provided in Example 1 as the main ingredient and adding auxiliary materials. The preparation method has a reasonable process and the quality of the obtained granules is stable and controllable. The preparation method specifically includes the following steps:

[0034] According to the mass ratio of 1:1, the traditional Chinese medicine extract and auxiliary materials are taken, and the auxiliary materials include microcrystalline cellulose and dextrin with a mass ratio of 1:3; the soft material is mixed evenly, and the soft material is placed in a granulator to granulate to obtain a coarse product , the crude product is dried by temperature programming: first, the temperature is raised to 35°C and the speed of ventilation is kept at 4m / s for 1h; Pass through No. 1 sieve and No. 4 sieve successively for sizing to obtain compound g...

Embodiment 3

[0036] This example provides a compound granule and its preparation method. The granule is prepared by using the traditional Chinese medicine extract provided in Example 1 as the main ingredient and adding auxiliary materials. The preparation method has a reasonable process and the quality of the obtained granules is stable and controllable. The preparation method specifically includes the following steps:

[0037] According to the mass ratio of 2:3, take the traditional Chinese medicine extract and auxiliary materials, the auxiliary materials include microcrystalline cellulose and dextrin with a mass ratio of 1:4; mix evenly to make soft material, and the soft material is placed in a granulator and squeezed through 10 mesh Sieve and granulate the crude product, and dry the crude product by temperature programming: first raise the temperature to 35°C and keep the speed of 4m / s for 1h; then raise the temperature to 43°C and dry for 1h; finally raise the temperature to 50°C and d...

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Abstract

The invention discloses compound granules and a preparation method thereof and relates to the field of pharmaceutical preparations. The compound granules disclosed by the invention are prepared by extracting raw materials including fructus mali torangoades, radix astragali seu hedysari, rhizoma anemarrhenae, radix ophiopogonis, red paeony root, fructus lycii, radix et rhizoma salviae miltiorrhizaeand rhizoma dioscoreae to obtain extract and adding auxiliary materials. The fructus mali torangoades is used as a modern pharmaceutical preparation and an application field of the fructus mali torangoades is expanded; the prepared preparation is stable and has controllable quality; the fructus mali torangoades extract is used as a main effective component of the granules and various types of medicine extract capable of resisting hypertension, hyperglycemia and hyperlipidemia are added; the medicines have a synergistic effect and the curative effect is enhanced. According to the preparation method of the compound granules, provided by the invention, the method is reasonable and feasible; the granularity of the granules obtained by the method is uniform and the granules are not easy to crush.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to compound granules and a preparation method thereof. Background technique [0002] The "three highs" refer to high blood pressure, high blood sugar (diabetes) and hyperlipidemia. They are the "diseases of wealth" derived from modern society. They may exist alone or may be related to each other. With the improvement of living standards and changes in the rhythm of life, the "three highs" have become like "the old swallows before Wang Xietang, flying into the homes of ordinary people", especially the common diseases of the middle-aged and elderly people over 50 years old, and they have recently become obvious. rejuvenation trend. The number of people who die from cardiovascular and cerebrovascular diseases is as high as 15 million every year in the world, ranking first among various causes of death. Cardiovascular and cerebrovascular diseases have become the "number one ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/16A61K47/36A61K47/38A61P3/10A61P3/06A61P9/12
CPCA61K9/1652A61K36/481A61K36/537A61K36/65A61K36/71A61K36/73A61K36/815A61K36/8945A61K36/8964A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 谢雨蕉雷敏李敏毛羽
Owner 炉霍雪域俄色有限责任公司