Platycodon grandiflorum fluid extract and preparation method thereof

Abstract

The invention discloses a platycodon grandiflorum fluid extract. The platycodon grandiflorum fluid extract comprises the following components in parts by weight: 10 to 20 parts of platycodon grandiflorum, 20 to 30 parts of 70 wt% ethanol, 4 to 6 parts of magnesium stearate, 2 to 4 parts of magnoflorine and 0.04 to 0.06 part of propolis. The platycodon grandiflorum fluid extract has the following beneficial effects: the platycodon grandiflorumn and the 70 wt% ethanol are slowly heated to prevent volatilization loss of ethanol, the magnesium stearate is added and slowly heated to guarantee the activity of the platycodon grandiflorumn and 70 wt% ethanol, and the cream is prepared through centrifugal concentration, so that the preparation cycle is greatly shortened; furthermore, the loss of effective components is almost avoided and the ethanol is volatilized as much as possible in the concentration process, so that the alcohol content of the finished product is reduced and damage to a human body is reduced.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to platycodon grandiflora fluid extract and a preparation method thereof. Background technique [0002] Extraction preparation: A type of preparation for internal or external use obtained by extracting active ingredients from animal and plant medicinal materials with appropriate extraction solvents and methods, and then properly refined and concentrated. Leaching preparations have a long history in China. The earliest record is in 1766 BC in Shang Tang's "Yi Yin Created Soup". Following the decoction, there are liquor, tincture, liquid extract, extract and decoction. In recent years, using modern science and technology and equipment to carry out experimental research on leaching preparations, many new varieties of leaching preparations have been developed, new technologies and new processes have been used to extract effective parts or multiple active ingredients in medicinal materials, and ...

AI Technical Summary

Problems solved by technology

The percolation method is used to extract the active ingredients of Platycodon grandiflorum in the above method, but there are problems such as cumbersome process, long production cycle, easy volatilization loss of ethanol during the percolation process, resulting in concentration changes, low recovery rate of active ingredients, etc.

Chinese Invention Patent Application No. CN201110248336.6 discloses the preparation method of Platycodon grandiflorum fluid extract, which uses membrane pressure filtration cycle extraction and separation integration technology to replace percolation method to prepare Platycodon grandiflorum fluid extract, simplifies the process flow, greatly shortens the production cycle, and reduces the extraction solvent The amount of ethanol is reduced, and the recovery rate of active ingredients is greatly improved, but some active ingredients will be lost after repeated membrane filter press cycle extraction, resulting in a low utilization rate of raw materials