Ruhe Neixiao granule for treating mammary lobular hyperplasia and mammary fibroma and preparation method thereof

A technology for breast lobular hyperplasia and breast fibroids, which is applied in the directions of medical preparations, antineoplastic drugs, and pharmaceutical formulations containing active ingredients, can solve the problems of unstable, unstable, and low oil yield of volatile oils, and achieves improved The effect of extracting transfer rate, improving stability, and improving transfer rate

Active Publication Date: 2021-02-26
KANGSHOU PHARMACY CO LTD HUNAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Ruhe Neixiao Granule is a Chinese patent medicine that softens hard masses, relieves liver and activates blood circulation, and treats menstrual breast pain and lumps, irregular menstruation, less volume, purple lumps, and breast hyperplasia. The national drug standard YBZ13552005-2012Z -1 records that the prescription is: Fritillaria 600g, Angelica 350g, Radix Paeoniae Rubra 600g, Lulu 350g, Rubia 600g, Cyperus Cyperi 300g, Bupleurum 500g, Tangerine Pit 300g, Prunella vulgaris 500g, Loofah 150g, Curcuma 500g, Licorice 75g, this prescription has a certain therapeutic effect on breast lobular hyperplasia and breast fibroadenoma, but the curative effect is not significant. At present, special effective drugs are still needed to treat breast lobular hyperplasia and breast fibroadenoma
Angelica is an essential ingredient of Ruhe Neixiao Granules. In the traditional method, water vapor is used to extract the volatile oil of Angelica sinensis. The oil and water are not easy to separate, the oil recovery rate is low, the heat-sensitive active ingredients are lost, the medicinal effect is not fully preserved, and the nature of the volatile oil is extremely unstable. , the oil-water mixture is sprayed into the preparation, and there are disadvantages such as inhomogeneous properties of the preparation, instability, easy moisture exceeding the standard, and difficulty in storage.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The Ruhe Neosiao granule in the present invention is made up of the following components in parts by weight: 10 parts of Fritillaria japonicus, 10 parts of Angelica sinensis, 15 parts of Radix Paeoniae Rubra, 7.5 parts of Loulu, 15 parts of madder, 7.5 parts of Rhizoma Cyperi, 10 parts of Hu, 10 parts of orange core, 15 parts of Prunella vulgaris, 5 parts of loofah, 10 parts of turmeric, 5 parts of licorice, 10 parts of Motherwort, 10 parts of Araceae, 15 parts of oysters, 5 parts of Salvia, 7.5 parts of Shanzi mushroom, 10 parts of seaweed, 10 parts of curcuma, 7.5 parts of poria cocos, 10 parts of astragalus, 7.5 parts of myrrh, 7.5 parts of green bark, 7.5 parts of xanthum, 10 parts of frankincense, 10 parts of trigonum, 10 parts of kelp, 15 parts of saponins, 7.5 parts of dandelion 10 parts of Caulis Spatholobus, 3 parts of powdered sugar, 90 parts of dextrin, and 3 parts of stevia.

[0021] The preparation method of the above-mentioned Ruhe internal elimination gra...

Embodiment 2

[0029] The Ruhe Neixiao Granules in the present invention are made up of the following components in parts by weight: 1 part of Fritillaria japonicus, 5 parts of Angelica sinensis, 5 parts of Radix Paeoniae Rubra, 1 part of Loulu, 10 parts of madder, 1 part of Rhizoma Cyperi, 5 parts of Hu, 1 part of Tangerine Pit, 10 parts of Prunella vulgaris, 1 part of Loofah, 1 part of Curcuma, 1 part of Licorice, 5 parts of Motherwort, 5 parts of Araceae, 10 parts of Oyster, 1 part of Salvia, 1 part of Shanzi Mushroom, 5 parts of seaweed, 5 parts of curcuma, 1 part of poria cocos, 1 part of astragalus, 1 part of myrrh, 1 part of green bark, 1 part of xanthophyll seed, 5 parts of frankincense, 5 parts of trigonum, 5 parts of kelp, 5 parts of saponins, 1 part of dandelion 5 parts of Caulis Spatholobus, 1 part of powdered sugar, 80 parts of dextrin, and 1 part of stevia.

[0030] The preparation method of the above-mentioned Ruhe internal elimination granule comprises the following steps:

...

Embodiment 3

[0038] The Ruhe Neixiao granule in the present invention is made up of the following components in parts by weight: 20 parts of Fritillaria japonicus, 15 parts of Angelica sinensis, 15 parts of Radix Paeoniae Rubra, 15 parts of Loulu, 20 parts of madder, 15 parts of Rhizoma Cyperi, 15 parts of Hu, 20 parts of orange core, 20 parts of Prunella vulgaris, 10 parts of loofah, 20 parts of turmeric, 10 parts of licorice, 15 parts of motherwort, 15 parts of Araceae, 20 parts of oysters, 10 parts of salvia miltiorrhiza, 15 parts of Shanzi mushroom, 15 parts of seaweed, 15 parts of curcuma, 15 parts of poria cocos, 20 parts of astragalus, 15 parts of myrrh, 15 parts of green skin, 15 parts of xanthophyll seed, 15 parts of frankincense, 15 parts of trigonum, 15 parts of kelp, 20 parts of saponins, 15 parts of dandelion 15 parts of Caulis Spatholobus, 5 parts of powdered sugar, 100 parts of dextrin, and 5 parts of stevia.

[0039] The preparation method of the above-mentioned Ruhe intern...

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PUM

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Abstract

The invention relates to Ruhe Neixiao Granules for treating mammary lobular hyperplasia and mammary fibroids and a preparation method thereof. The composition is as follows: 1-20 parts of Fritillaria japonicus, 5-15 parts of Angelica sinensis, 5-15 parts of Radix Paeoniae Rubra, 1-15 parts of leaking reed, 10-20 parts of madder, 1-15 parts of Cyperus cyperi, 5-15 parts of Bupleurum, 1-20 parts of orange pit, 10-20 parts of Prunella vulgaris, 1-10 parts of loofah, turmeric 1 to 20 parts, 1 to 10 parts of licorice, 5 to 15 parts of motherwort, 5 to 15 parts of Araceae, 10 to 20 parts of oyster, 1 to 10 parts of salvia miltiorrhiza, 1 to 15 parts of Shanzi mushroom, 5 to 15 parts of seaweed, zedoary 5-15 parts, 1-15 parts of Poria, 1-20 parts of Astragalus, 1-15 parts of Myrrh, 1-15 parts of Qingpi, 1-15 parts of Xanthogonia, 5-15 parts of frankincense, 5-15 parts of trigonum, kelp 5 to 15 parts, 5 to 20 parts of saponins, 1 to 15 parts of dandelion, and 5 to 15 parts of Spatholobus. The Ruhe Neixiao granule of the present invention is mainly used for treating breast lobular hyperplasia and breast fibroma, and has remarkable curative effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to Ruhe Neixiao Granules for treating mammary lobular hyperplasia and mammary fibroma and a preparation method thereof. Background technique [0002] Breast lobular hyperplasia is the most common non-neoplastic, non-inflammatory proliferative lesion, and is the most common breast disease in women. May occur at any age after puberty. The lesion is a pathological process dominated by dilatation, hyperplasia and cystic changes of gland lobules and mammary duct terminals. Modern medicine believes that the occurrence of this disease is related to ovarian dysfunction, the secretion of progesterone is reduced, and the secretion of estrogen is relatively increased. Traditional Chinese medicine attributes this disease to the category of breast addiction, which is closely related to the liver, stomach, Chong, Ren and other meridians. Liver Qi is not relaxed and stagna...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/16A61P15/14A61P35/00A61K35/618
CPCA61K9/1652A61K35/618A61K36/02A61K36/03A61K36/076A61K36/232A61K36/233A61K36/28A61K36/288A61K36/324A61K36/328A61K36/42A61K36/481A61K36/483A61K36/484A61K36/486A61K36/533A61K36/536A61K36/537A61K36/65A61K36/71A61K36/74A61K36/752A61K36/8884A61K36/8905A61K36/8945A61K36/8966A61K36/898A61K36/902A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 谈发金王志锋柳卓
Owner KANGSHOU PHARMACY CO LTD HUNAN
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